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Neuroscience

D-Index
50
Citations
9770
World Ranking
5719
National Ranking
2526

Overview

Javier González-Maeso is affiliated with Virginia Commonwealth University in the United States. Their research primarily spans the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields including Cellular and Molecular Neuroscience, Molecular Biology, Clinical Psychology, Organic Chemistry, and Biological Psychiatry.

Their work covers a range of main topics such as Neurotransmitter Receptor Influence on Behavior, Psychedelics and Drug Studies, Chemical Synthesis and Alkaloids, Receptor Mechanisms and Signaling, Tryptophan and Brain Disorders, Neuroscience and Neuropharmacology Research, and Epigenetics and DNA Methylation.

Among recent publications, notable papers include the following:

  • Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice, 2021, Cell Reports
  • Structural and Biophysical Mechanisms of Class C G Protein-Coupled Receptor Function, 2020, Trends in Biochemical Sciences
  • G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs), 2021, Pharmacology & Therapeutics
  • Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice, 2022, ACS Chemical Neuroscience
  • Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice, 2022, Nature Communications

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Molecular Psychiatry, Neuropharmacology, and ACS Chemical Neuroscience.

They have collaborated extensively with co-authors including Mario de la Fuente Revenga, Salvador Sierra, J. Javier Meana, Alaina M. Jaster, and Justin M. Saunders.

Best Publications

  • Hallucinogens Recruit Specific Cortical 5-HT2A Receptor-Mediated Signaling Pathways to Affect Behavior

    Javier González-Maeso;Noelia V. Weisstaub;Mingming Zhou;Pokman Chan

  • Identification of a serotonin/glutamate receptor complex implicated in psychosis

    Javier González-Maeso;Rosalind L. Ang;Tony Yuen;Pokman Chan

  • Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

    Noelia V. Weisstaub;Mingming Zhou;Alena Lira;Evelyn Lambe;Evelyn Lambe

  • Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression

    Sam A Golden;Daniel J Christoffel;Mitra Heshmati;Georgia E Hodes

  • Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs

    Miguel Fribourg;José L. Moreno;Terrell Holloway;Davide Provasi

  • Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-Hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex

    Javier González-Maeso;Tony Yuen;Barbara J. Ebersole;Elisa Wurmbach

  • HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

    Mitsumasa Kurita;Terrell Holloway;Aintzane García-Bea;Aintzane García-Bea;Alexey Kozlenkov

  • Hallucinogens and Serotonin 5-HT 2A Receptor-Mediated Signaling Pathways

    Juan F. López-Giménez;Javier González-Maeso

  • Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists

    José L. Moreno;Terrell Holloway;Laura Albizu;Stuart C. Sealfon

  • Method for multiplex cellular detection of mRNAs using quantum dot fluorescent in situ hybridization

    PokMan Chan;Tony Yuen;Frederique Ruf;Javier Gonzalez-Maeso

  • Psychedelics and schizophrenia

    Javier González-Maeso;Stuart C. Sealfon

  • Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice

    Mario de la Fuente Revenga;Bohan Zhu;Christopher A. Guevara;Lynette B. Naler

  • Animal models of serotonergic psychedelics.

    James B Hanks;Javier González-Maeso

  • Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function

    José L. Moreno;Carolina Muguruza;Adrienne Umali;Steven Mortillo

  • Prenatal Stress Induces Schizophrenia-Like Alterations of Serotonin 2A and Metabotropic Glutamate 2 Receptors in the Adult Offspring: Role of Maternal Immune System

    Terrell Holloway;José L. Moreno;Adrienne Umali;Vinayak Rayannavar

  • Maternal Influenza Viral Infection Causes Schizophrenia-Like Alterations of 5-HT2A and mGlu2 Receptors in the Adult Offspring

    José L. Moreno;Mitsumasa Kurita;Terrell Holloway;Javier López

  • Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia

    José L. Moreno;José L. Moreno;Patricia Miranda-Azpiazu;Aintzane García-Bea;Aintzane García-Bea;Jason Younkin

  • Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors

    Laura Albizu;Terrell Holloway;Javier González-Maeso;Stuart C. Sealfon

  • Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of α2A-adrenoceptors

    J González-Maeso;R Rodríguez-Puertas;J J Meana;J J Meana;J A García-Sevilla

  • p53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition

    Venugopalan D. Nair;Kevin St. P. McNaught;Javier González-Maeso;Stuart C. Sealfon

  • Distribution of prolyl endopeptidase activities in rat and human brain.

    Jon Irazusta;Gorka Larrinaga;Javier González-Maeso;Javier Gil

Frequent Co-Authors

J. Javier Meana
J. Javier Meana University of the Basque Country
Rachael L. Neve
Rachael L. Neve Harvard University
Alberto Fernández-Teruel
Alberto Fernández-Teruel Autonomous University of Barcelona
Scott J. Russo
Scott J. Russo Icahn School of Medicine at Mount Sinai
Angel Pazos
Angel Pazos University of Cantabria
Jay A. Gingrich
Jay A. Gingrich Columbia University
Salvador Martinez
Salvador Martinez Miguel Hernandez University
Evelyn K. Lambe
Evelyn K. Lambe University of Toronto
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Sam A. Golden
Sam A. Golden University of Washington

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