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Leo A. J. Kluijtmans

Leo A. J. Kluijtmans

Radboud University
Netherlands

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
16714
World Ranking
16939
National Ranking
413

Leo A. J. Kluijtmans publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Leo A. J. Kluijtmans sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 142 publications — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Leo A. J. Kluijtmans D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Leo A. J. Kluijtmans sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 51 D-Index — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Leo A. J. Kluijtmans is affiliated with Radboud University in the Netherlands. Their research spans several interconnected fields within biochemistry, genetics, molecular biology, and medicine. The main focus areas include metabolism and genetic disorders, metabolomics and mass spectrometry studies, genomics and rare diseases, mitochondrial function and pathology, diet and metabolism studies, bioinformatics and genomic networks, and liver disease diagnosis and treatment.

Their scholarly output comprises publications in a range of journals and venues, with frequent contributions to:

  • JIMD Reports
  • Genetics in Medicine
  • Metabolites
  • Metabolomics
  • bioRxiv (Cold Spring Harbor Laboratory)

Subfields of study that characterize their work include molecular biology, clinical biochemistry, genetics, physiology, and epidemiology. These areas frame a multidisciplinary approach to understanding biochemical and genetic processes underlying human health.

Notable recent papers authored or co-authored by Leo A. J. Kluijtmans include:

  • Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy, 2021, Journal of Clinical Investigation
  • Amadori rearrangement products as potential biomarkers for inborn errors of amino-acid metabolism, 2021, Communications Biology
  • Metabolite Identification Using Infrared Ion SpectroscopyNovel Biomarkers for Pyridoxine-Dependent Epilepsy, 2021, Analytical Chemistry
  • Cerebrotendinous xanthomatosis without neurological involvement, 2021, Journal of Internal Medicine
  • A comparison of high-throughput plasma NMR protocols for comparative untargeted metabolomics, 2020, Metabolomics

Collaboration is a consistent element of their research, with frequent co-authors being:

  • Udo F. H. Engelke
  • Ron A. Wevers
  • Karlien L. M. Coene
  • Marleen C.D.G. Huigen
  • Clara D.M. van Karnebeek

Their publication record reflects involvement in 60 articles classified under biochemistry, genetics, and molecular biology, and 32 under medicine. This demonstrates a breadth of research integrating molecular insights with clinical applications.

Best Publications

  • A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

    P. Frosst;H. J. Blom;R. Milos;P. Goyette

  • Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.

    L. A. J. Kluijtmans;L. P. W. J. Van Den Heuvel;G. H. J. Boers;P. Frosst

  • FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study.

    Anu Suomalainen;Anu Suomalainen;Jenni M Elo;Kirsi H Pietiläinen;Anna H Hakonen

  • Homocysteine Determinants and the Evidence to What Extent Homocysteine Determines the Risk of Coronary Heart Disease

    Angelika De Bree;W. M. Monique Verschuren;Daan Kromhout;Leo A. J. Kluijtmans

  • Cystathionine β‐synthase mutations in homocystinuria

    Jan P. Kraus;Miroslav Janošík;Viktor Kožich;Roseann Mandell

  • The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations

    Derval J Gaughan;Leo A.J Kluijtmans;Sandrine Barbaux;Dorothy McMaster

  • Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.

    Leo A. J. Kluijtmans;Ian S. Young;Colin A. Boreham;Liam Murray

  • Exome Sequencing and the Management of Neurometabolic Disorders

    Maja Tarailo-Graovac;Maja Tarailo-Graovac;Casper Shyr;Colin J. Ross;Gabriella A. Horvath;Gabriella A. Horvath

  • Thermolabile Methylenetetrahydrofolate Reductase in Coronary Artery Disease

    L.A.J. Kluijtmans;J.J.P. Kastelein;J. Lindemans;G.H.J. Boers

  • Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease.

    N. M. J. Van Der Put;E. F. Van Der Molen;L. A. J. Kluijtmans;S. G. Heil

  • SUCLA2 mutations are associated with mild methylmalonic aciduria, Leigh-like encephalomyopathy, dystonia and deafness.

    Rosalba Carrozzo;Carlo Dionisi-Vici;Ulrike Steuerwald;Simona Lucioli

  • Mutations in the phospholipid remodeling gene SERAC1 impair mitochondrial function and intracellular cholesterol trafficking and cause dystonia and deafness

    Saskia B Wortmann;Frédéric M Vaz;Thatjana Gardeitchik;Lisenka E L M Vissers

  • Does the Interaction between Maternal Folate Intake and the Methylenetetrahydrofolate Reductase Polymorphisms Affect the Risk of Cleft Lip with or without Cleft Palate

    Iris A. L. M. van Rooij;Christl Vermeij-Keers;Leo A. J. Kluijtmans;Marga C. Ocké

  • A second common variant in the methylenetetrahydrofolate reductase (MTHFR) gene and its relationship to MTHFR enzyme activity, homocysteine, and cardiovascular disease risk

    Karin J. A. Lievers;Godfried H. J. Boers;Petra Verhoef;Martin Den Heijer

  • Next-generation metabolic screening: targeted and untargeted metabolomics for the diagnosis of inborn errors of metabolism in individual patients

    Karlien L. M. Coene;Leo A. J. Kluijtmans;Ed van der Heeft;Udo F. H. Engelke

  • The 677C->T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease

    Petra Verhoef;Frans J Kok;Leo A.J Kluijtmans;Henk J Blom

  • NANS-mediated synthesis of sialic acid is required for brain and skeletal development

    Clara D M van Karnebeek;Luisa Bonafé;Xiao-Yan Wen;Xiao-Yan Wen;Maja Tarailo-Graovac

  • The molecular basis of cystathionine beta-synthase deficiency in Dutch patients with homocystinuria: effect of CBS genotype on biochemical and clinical phenotype and on response to treatment.

    Leo A.J. Kluijtmans;Godfried H.J. Boers;Jan P. Kraus;Lambert P. W.J. van den Heuvel

  • Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient.

    L.A.J. Kluijtmans;G.H.J. Boers;E.M.B. Stevens;W.O. Renier

  • 3-Methylglutaconic aciduria--lessons from 50 genes and 977 patients

    Saskia B. Wortmann;Leo A. J. Kluijtmans;Richard J. Rodenburg;Jörn Oliver Sass

Frequent Co-Authors

Ron A. Wevers
Ron A. Wevers Radboud University
Henk J. Blom
Henk J. Blom Erasmus MC
Eva Morava
Eva Morava Mayo Clinic
Jos Oomens
Jos Oomens Radboud University
Martin den Heijer
Martin den Heijer University of Amsterdam
Frans J.M. Trijbels
Frans J.M. Trijbels Radboud University
Richard J. Rodenburg
Richard J. Rodenburg Radboud University
Alexander S. Whitehead
Alexander S. Whitehead University of Pennsylvania
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Giel Berden
Giel Berden Radboud University

External Links

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Best Scientists Citing Leo A. J. Kluijtmans

Rima Rozen

Rima Rozen

McGill University

Publications: 108

Henk J. Blom

Henk J. Blom

Erasmus MC

Publications: 106

Per Magne Ueland

Per Magne Ueland

University of Bergen

Publications: 68

John M. Scott

John M. Scott

Trinity College Dublin

Publications: 60

Anne M. Molloy

Anne M. Molloy

Trinity College Dublin

Publications: 59

Jacob Selhub

Jacob Selhub

Tufts University

Publications: 48

Helga Refsum

Helga Refsum

University of Oslo

Publications: 43

Alexander S. Whitehead

Alexander S. Whitehead

University of Pennsylvania

Publications: 39

Ron A. Wevers

Ron A. Wevers

Radboud University

Publications: 38

Cornelia M. Ulrich

Cornelia M. Ulrich

University of Utah

Publications: 37

Richard H. Finnell

Richard H. Finnell

Baylor College of Medicine

Publications: 32

Ruma Banerjee

Ruma Banerjee

University of Michigan–Ann Arbor

Publications: 31

Jan P. Kraus

Jan P. Kraus

University of Colorado Denver

Publications: 31

Régine P.M. Steegers-Theunissen

Régine P.M. Steegers-Theunissen

Erasmus University Rotterdam

Publications: 31

Shamima Rahman

Shamima Rahman

University College London

Publications: 29

James L. Mills

James L. Mills

National Institutes of Health

Publications: 28

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