Kazuo Nagai

Overview

Best Publications

• Synthesis and sequence-specific proteolysis of hybrid proteins produced in Escherichia coli.

  Kiyoshi Nagai;Hans Christian Thøgersen

  538
  Citations

• Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.

  T Kataoka;N Shinohara;H Takayama;K Takaku

  452
  Citations

• Synthesis and Antibacterial Activity of a Novel Series of Potent DNA Gyrase Inhibitors. Pyrazole Derivatives

  Akihiko Tanitame;Yoshihiro Oyamada;Keiko Ofuji;Mika Fujimoto

  358
  Citations

• Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (−)-epigallocatechin gallate

  Hiroshi Nakagawa;Keiji Hasumi;Je-Tae Woo;Kazuo Nagai

  285
  Citations

• Novel S-Benzylisothiourea Compound That Induces Spherical Cells in Escherichia coli Probably by Acting on a Rod-shape-determining Protein(s) Other Than Penicillin-binding Protein 2

  Noritaka Iwai;Kazuo Nagai;Masaaki Wachi

  233
  Citations

• Prodigiosins as a New Group of H+/Cl−Symporters That Uncouple Proton Translocators

  Tomohiko Sato;Hiroki Konno;Yasufumi Tanaka;Takao Kataoka

  215
  Citations

• Suppression of Osteoprotegerin Expression by Prostaglandin E2 Is Crucially Involved in Lipopolysaccharide-Induced Osteoclast Formation

  Koji Suda;Nobuyuki Udagawa;Nobuaki Sato;Masamichi Takami

  213
  Citations

• Fenton Reaction Is Primarily Involved in a Mechanism of (−)-Epigallocatechin-3-gallate to Induce Osteoclastic Cell Death ☆

  Hiroshi Nakagawa;Masaaki Wachi;Je-Tae Woo;Masanori Kato

  210
  Citations

• Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice

  Young-Sil Lee;Byung-Yoon Cha;Kiyoto Saito;Hiroshi Yamakawa

  195
  Citations

• Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring.

  Akihiko Tanitame;Yoshihiro Oyamada;Keiko Ofuji;Mika Fujimoto

  187
  Citations

• Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice.

  Young-Sil Lee;Byung-Yoon Cha;Sun-Sil Choi;Bong-Keun Choi

  186
  Citations

• Safflower polysaccharides activate the transcription factor NF-κB via Toll-like receptor 4 and induce cytokine production by macrophages

  Izuru Ando;Yoshinori Tsukumo;Tetsuya Wakabayashi;Sachiko Akashi

  176
  Citations

• Acidification is essential for maintaining the structure and function of lytic granules of CTL. Effect of concanamycin A, an inhibitor of vacuolar type H(+)-ATPase, on CTL-mediated cytotoxicity.

  T Kataoka;K Takaku;J Magae;N Shinohara

  171
  Citations

• Escherichia coli cafA gene encodes a novel RNase, designated as RNase G, involved in processing of the 5' end of 16S rRNA.

  Masaaki Wachi;Genryou Umitsuki;Miwa Shimizu;Ayako Takada

  157
  Citations

• Guaianolides as immunomodulators. Synthesis and biological activities of dehydrocostus lactone, mokko lactone, eremanthin, and their derivatives.

  Saori Yuuya;Hisahiro Hagiwara;Toshio Suzuki;Masayoshi Ando

  154
  Citations

• An antibiotic, ascofuranone, specifically inhibits respiration and in vitro growth of long slender bloodstream forms of Trypanosoma brucei brucei.

  Nobuko Minagawa;Yoshisada Yabu;Kiyoshi Kita;Kazuo Nagai

  146
  Citations

• Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts.

  Je-Tae Woo;Hiroshi Nakagawa;Michitaka Notoya;Takayuki Yonezawa

  140
  Citations

• Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-, IL-1 and RANKL

  Koji Suda;Je-Tae Woo;Masamichi Takami;Patrick M. Sexton

  137
  Citations

• Effects of high hydrostatic pressure on bacterial cytoskeleton FtsZ polymers in vivo and in vitro.

  Akihiro Ishii;Akihiro Ishii;Takako Sato;Masaaki Wachi;Kazuo Nagai

  128
  Citations

• Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells.

  Sun-Sil Choi;Byung-Yoon Cha;Young-Sil Lee;Takayuki Yonezawa

  127
  Citations