World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
92
Citations
36052
World Ranking
2188
National Ranking
24

Research.com Recognitions

  • 2016 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences for their fundamental contributions to understanding the structural basis for ATP-driven translocation of ions across membranes

Overview

Poul Nissen is affiliated with Aarhus University in Denmark. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Materials Chemistry, Oncology, Cell Biology, and Cellular and Molecular Neuroscience.

The main topics of Nissen's work include:

  • ATP Synthase and ATPases Research
  • Enzyme Structure and Function
  • Ion Transport and Channel Regulation
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Ion channel regulation and function
  • Amino Acid Enzymes and Metabolism

Frequent collaborators in their research include Joseph A. Lyons, Caroline Neumann, Thibaud Dieudonné, Michael Habeck, and Rasmus Kock Flygaard.

Nissen has published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Molecular Biology, The EMBO Journal, Nature Communications, and Journal of Applied Crystallography.

Selected recent papers authored or co-authored by Nissen are:

  • "Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components" (2020) published in Cell Communication and Signaling
  • "Structural insights into the inhibition of glycine reuptake" (2021) published in Nature
  • "Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling" (2022) published in Journal of Molecular Biology
  • "X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release" (2020) published in Nature Communications
  • "Structure and Function of Na,K-ATPase-The Sodium-Potassium Pump" (2021) published in Comprehensive Physiology

In addition to journal articles, Poul Nissen has contributed to book publications, including a title published by King's College London in 2024: Dansk strategisk forskning - nu og i fremtiden:Hvidbog til Forskningspolitisk Årsmøde 2024.

The scientist was awarded the Gregori Aminoff Prize by the Royal Swedish Academy of Sciences in 2016 for their work related to the structural basis for ATP-driven ion translocation across membranes.

Best Publications

  • The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.

    Nenad Ban;Poul Nissen;Jeffrey L. Hansen;Peter B. Moore

  • The Structural Basis of Ribosome Activity in Peptide Bond Synthesis

    Poul Nissen;Jeffrey Hansen;Nenad Ban;Peter B. Moore

  • Crystal Structure of the Ternary Complex of Phe-tRNAPhe, EF-Tu, and a GTP Analog

    Poul Nissen;Morten Kjeldgaard;Søren Thirup;Galina Polekhina

  • Crystal structure of the sodium–potassium pump

    J. Preben Morth;J. Preben Morth;Bjørn P. Pedersen;Bjørn P. Pedersen;Mads S. Toustrup-Jensen;Mads S. Toustrup-Jensen;Thomas L.-M. Sørensen

  • RNA tertiary interactions in the large ribosomal subunit: the A-minor motif.

    Poul Nissen;Joseph A. Ippolito;Nenad Ban;Peter B. Moore

  • The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit

    Jeffrey L. Hansen;Joseph A. Ippolito;Nenad Ban;Poul Nissen

  • P-Type ATPases

    Michael G. Palmgren;Poul Nissen

  • Lithium isotopic abundances in metal-poor halo stars

    Martin Asplund;David L. Lambert;Poul Erik Nissen;Francesca Primas

  • Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.

    Elena A B Azizan;Hanne Poulsen;Petronel Tuluc;Junhua Zhou

  • Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit.

    Nenad Ban;Nenad Ban;Poul Nissen;Jeffrey Hansen;Jeffrey Hansen;Malcolm Capel

  • The structural basis of calcium transport by the calcium pump

    Claus Olesen;Martin Picard;Martin Picard;Anne-Marie Lund Winther;Anne-Marie Lund Winther;Claus Gyrup

  • The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation.

    Morten Kjeldgaard;Poul Nissen;Søren Thirup;Jens Nyborg

  • A structural overview of the plasma membrane Na + ,K + -ATPase and H + -ATPase ion pumps

    J. Preben Morth;Bjørn P. Pedersen;Bjørn P. Pedersen;Bjørn P. Pedersen;Morten J. Buch-Pedersen;Morten J. Buch-Pedersen;Jens Peter Andersen;Jens Peter Andersen

  • Crystal structure of a plasma membrane proton pump

    Michael G. Palmgren;Morten Buch-Pedersen;Bjørn Pañella Pedersen;Poul Nissen

  • Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy

    Mikel Valle;Andrey Zavialov;Wen Li;Scott M Stagg

  • A 9 Å Resolution X-Ray Crystallographic Map of the Large Ribosomal Subunit

    Nenad Ban;Betty Freeborn;Poul Nissen;Pawel Penczek;Pawel Penczek

  • Crystal structure of a copper-transporting PIB-type ATPase.

    Pontus Gourdon;Xiang-Yu Liu;Xiang-Yu Liu;Tina Skjørringe;J Preben Morth;J Preben Morth

  • Namdinator - automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps.

    Rune Thomas Kidmose;Jonathan Juhl;Poul Nissen;Thomas Boesen

  • Structural diversity of calmodulin binding to its target sites

    Henning Tidow;Poul Nissen

  • The structural basis of calcium transport by the calcium pump

    C. Olesen;M. Picard;A.-M.L. Winther;C.G. Nielsen

Frequent Co-Authors

Jesper V. Møller
Jesper V. Møller Aarhus University
Thomas A. Steitz
Thomas A. Steitz Yale University
Jens Peter Andersen
Jens Peter Andersen Aarhus University
Nenad Ban
Nenad Ban ETH Zurich
Martin Asplund
Martin Asplund Australian National University
Michael G. Palmgren
Michael G. Palmgren University of Copenhagen
Göran Lindblom
Göran Lindblom Umeå University
Anders Liljas
Anders Liljas Lund University
Bente Vilsen
Bente Vilsen Aarhus University
David L. Lambert
David L. Lambert The University of Texas at Austin

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