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Chemistry

D-Index
59
Citations
13231
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10084
National Ranking
70

Biology and Biochemistry

D-Index
64
Citations
16494
World Ranking
9571
National Ranking
91

Research.com Recognitions

  • 2020 - Fellow of the Royal Society, United Kingdom
  • 2013 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • 2009 - Nobel Prize for studies of the structure and function of the ribosome
  • 2007 - Paul Ehrlich and Ludwig Darmstaedter Prize Weizmann Institute
  • 2006 - Wolf Prize in Chemistry, Wolf Foundation for ingenious structural discoveries of the ribosomal machinery of peptide-bond formation and the light-driven primary processes in photosynthesis.
  • 2005 - Fellow of the American Academy of Arts and Sciences
  • 2005 - Louisa Gross Horwitz Prize, Columbia University
  • 2004 - Paul Karrer Gold Medal, University of Zurich
  • 2003 - Member of the National Academy of Sciences
  • 2002 - F.A. Cotton Medal for Excellence in Chemical Research, American Chemical Society (ACS)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ada Yonath is affiliated with the Weizmann Institute of Science in Israel. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology and related subfields.

The scientist's work spans a range of topics, notably:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Trypanosoma species research and implications
  • Origins and Evolution of Life
  • Genomics and Phylogenetic Studies
  • Parasitic Infections and Diagnostics
  • Synthesis and Biological Evaluation

Ada Yonath's contributions to recent scientific literature include several papers such as:

  • "Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds," 2022, Nucleic Acids Research
  • "Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis," 2020, Nucleic Acids Research
  • "Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida," 2021, Nucleic Acids Research
  • "A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei," 2023, Nature Communications
  • "Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia," 2022, Nucleic Acids Research

Frequent coauthors collaborating with Ada Yonath include:

  • Anat Bashan
  • Ella Zimmerman
  • Tanaya Bose
  • André Rivalta
  • Disha-Gajanan Hiregange

Most of the scientist's publications have appeared in the following venues:

  • Nucleic Acids Research
  • Nature Communications
  • Cell Reports
  • Israel Journal of Chemistry
  • Proceedings of the National Academy of Sciences

Ada Yonath's research achievements have been recognized through various awards, including:

  • Nobel Prize (2009) for studies of the structure and function of the ribosome
  • Fellow of the Royal Society, United Kingdom (2020)
  • German National Academy of Sciences Leopoldina (2013) in Biochemistry and Biophysics
  • Paul Ehrlich and Ludwig Darmstaedter Prize (2007)
  • Wolf Prize in Chemistry, Wolf Foundation (2006) for discoveries related to ribosomal machinery and photosynthesis
  • Fellow of the American Academy of Arts and Sciences (2005)
  • Louisa Gross Horwitz Prize, Columbia University (2005)
  • Paul Karrer Gold Medal, University of Zurich (2004)
  • Member of the National Academy of Sciences (2003)
  • F.A. Cotton Medal for Excellence in Chemical Research, American Chemical Society (2002)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution

    Frank Schluenzen;Ante Tocilj;Raz Zarivach;Joerg Harms

  • Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

    Frank Schlünzen;Raz Zarivach;Jörg Harms;Anat Bashan

  • High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium

    Joerg Harms;Frank Schluenzen;Raz Zarivach;Anat Bashan

  • Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3

    Marta Pioletti;Marta Pioletti;Frank Schlünzen;Jörg Harms;Raz Zarivach

  • A new system for naming ribosomal proteins

    Nenad Ban;Roland Beckmann;Jamie H D Cate;Jonathan D Dinman

  • Structure of Functionally Activated Small Ribosomal Subunit

    Frank Schluenzen;Ante Tocilj;Raz Zarivach;Joerg Harms

  • Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression

    Anant Bashan;Ilana Agmon;Raz Zarivach;Frank Schluenzen

  • A tunnel in the large ribosomal subunit revealed by three-dimensional image reconstruction

    A Yonath;KR Leonard;HG Wittmann

  • A high resolution structure of an inhibitor complex of the extracellular nuclease of Staphylococcus aureus. I. Experimental procedures and chain tracing.

    A. Arnone;C.J. Bier;F.A. Cotton;V.W. Day

  • Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin

    Frank Schlünzen;Erez Pyetan;Paola Fucini;Ada Yonath

  • ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation

    Ada Yonath

  • Structural Basis for the Antibiotic Activity of Ketolides and Azalides

    Frank Schlunzen;Joerg M. Harms;Francois Franceschi;Harly A. S. Hansen

  • Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.

    Chen Davidovich;Anat Bashan;Tamar Auerbach-Nevo;Rachel D. Yaggie

  • Structural insight into the role of the ribosomal tunnel in cellular regulation.

    Rita Berisio;Frank Schluenzen;Joerg Harms;Anat Bashan

  • Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

    Jörg M Harms;Frank Schlünzen;Paola Fucini;Heike Bartels

  • Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants

    Rita Berisio;Joerg Harms;Frank Schluenzen;Raz Zarivach

  • Polymers of tripeptides as collagen models: IV. Structure analysis of poly(l-prolyl-glycyl-l-proline)

    A. Yonath;W. Traub

  • Characterization and preliminary attempts for derivatization of crystals of large ribosomal subunits from Haloarcula marismortui diffracting to 3 A resolution.

    K. von Böhlen;I. Makowski;H.A.S. Hansen;H. Bartels

  • Cryocrystallography of ribosomal particles.

    H. Hope;F. Frolow;K. von Böhlen;I. Makowski

  • The small ribosomal subunit from Thermus thermophilus at 4.5 A resolution: pattern fittings and the identification of a functional site.

    Ante Tocilj;Frank Schlünzen;Daniela Janell;Marco Glühmann

Frequent Co-Authors

Miriam Eisenstein
Miriam Eisenstein Weizmann Institute of Science
Joel L. Sussman
Joel L. Sussman Weizmann Institute of Science
Irit Sagi
Irit Sagi Weizmann Institute of Science
Felix Frolow
Felix Frolow Tel Aviv University
John Moult
John Moult University of Maryland, College Park
Nathan Sharon
Nathan Sharon Weizmann Institute of Science
Helle Krogh Johansen
Helle Krogh Johansen University of Copenhagen
Erik C. Böttger
Erik C. Böttger University of Zurich
Anton Y. Peleg
Anton Y. Peleg Monash University
Alexander S. Mankin
Alexander S. Mankin University of Illinois at Chicago

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