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Enrique M. De La Cruz

Enrique M. De La Cruz

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
9453
World Ranking
15196
National Ranking
6354

Overview

Enrique M. De La Cruz is affiliated with Yale University in the United States and focuses their research on the intersection of biochemistry, genetics, and molecular biology. Their work encompasses several subfields, including cell biology, molecular biology, atomic and molecular physics with optics, biophysics, and genetics.

The scientist has contributed to multiple topics related to cellular mechanics and interactions, force microscopy techniques and applications, advanced fluorescence microscopy techniques, cardiomyopathy and myosin studies, Toxoplasma gondii research studies, genetic and kidney cyst diseases, and hedgehog signaling pathway studies.

Frequent publication venues for De La Cruz include Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Journal of Biological Chemistry, and Biophysical Journal.

Among recent publications are:

  • Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments, 2020, Proceedings of the National Academy of Sciences
  • Force and phosphate release from Arp2/3 complex promote dissociation of actin filament branches, 2020, Proceedings of the National Academy of Sciences
  • Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway, 2021, Current Biology
  • Twist response of actin filaments, 2023, Proceedings of the National Academy of Sciences
  • Clusters of a Few Bound Cofilins Sever Actin Filaments, 2021, Journal of Molecular Biology

De La Cruz collaborates frequently with other researchers, including Wenxiang Cao, Charles V. Sindelar, Jeffrey P. Bibeau, Shawn Gray, and Nandan G. Pandit. These collaborations have contributed to the cross-disciplinary nature of their research output.

Best Publications

  • The kinetic mechanism of myosin V.

    Enrique M. De La Cruz;Amber L. Wells;Steven S. Rosenfeld;E. Michael Ostap

  • Relating biochemistry and function in the myosin superfamily.

    Enrique M De La Cruz;E Michael Ostap

  • Actin Network Architecture Can Determine Myosin Motor Activity

    Anne-Cécile Reymann;Rajaa Boujemaa-Paterski;Jean-Louis Martiel;Christophe Guérin

  • Kinetic Mechanism and Regulation of Myosin VI

    Enrique M. De La Cruz;E. Michael Ostap;H. Lee Sweeney

  • Cofilin increases the bending flexibility of actin filaments: implications for severing and cell mechanics.

    Brannon R McCullough;Laurent Blanchoin;Jean Louis Martiel;Enrique M. De La Cruz

  • Cofilin Tunes the Nucleotide State of Actin Filaments and Severs at Bare and Decorated Segment Boundaries

    Cristian Suarez;Jérémy Roland;Rajaa Boujemaa-Paterski;Hyeran Kang

  • Architecture and Connectivity Govern Actin Network Contractility.

    Hajer Ennomani;Gaëlle Letort;Christophe Guérin;Jean-Louis Martiel

  • Mechanochemical coupling of two substeps in a single myosin V motor.

    Sotaro Uemura;Hideo Higuchi;Adrian O Olivares;Enrique M De La Cruz

  • Interactions of Acanthamoeba profilin with actin and nucleotides bound to actin.

    Valda K. Vinson;Enrique M. De La Cruz;and Henry N. Higgs;Thomas D. Pollard

  • The Structural Basis for Activation of the Rab Ypt1p by the TRAPP Membrane-Tethering Complexes

    Yiying Cai;Harvey F. Chin;Darina Lazarova;Shekar Menon

  • Kinetic and equilibrium analysis of the myosin ATPase.

    Enrique M. De La Cruz;E. Michael Ostap

  • ADP Inhibition of Myosin V ATPase Activity

    Enrique M. De La Cruz;H. Lee Sweeney;E. Michael Ostap

  • Cofilin binding to muscle and non-muscle actin filaments: isoform-dependent cooperative interactions.

    Enrique M. De La Cruz

  • Cofilin-Linked Changes in Actin Filament Flexibility Promote Severing

    Brannon R McCullough;Elena E. Grintsevich;Christine K. Chen;Hyeran Kang

  • Cofilin Increases the Torsional Flexibility and Dynamics of Actin Filaments

    Ewa Prochniewicz;Neal Janson;David D. Thomas;Enrique M. De La Cruz

  • How cofilin severs an actin filament

    Enrique M. De La Cruz

  • The ATPase cycle mechanism of the DEAD-box rRNA helicase, DbpA

    Arnon Henn;Wenxiang Cao;David D. Hackney;Enrique M. De La Cruz

  • Actin filament remodeling by actin depolymerization factor/cofilin.

    Jim Pfaendtner;Enrique M. De La Cruz;Gregory A. Voth

  • Kinetics and Thermodynamics of Phalloidin Binding to Actin Filaments from Three Divergent Species

    E M De La Cruz;T D Pollard

  • ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy

    Ronald A. Albright;Paul Stabach;Wenxiang Cao;Dillon Kavanagh

Frequent Co-Authors

Laurent Blanchoin
Laurent Blanchoin Grenoble Alpes University
Gregory A. Voth
Gregory A. Voth University of Chicago
Thomas D. Pollard
Thomas D. Pollard Yale University
Jean-François Joanny
Jean-François Joanny Collège de France
H. Lee Sweeney
H. Lee Sweeney University of Florida
Frank Jülicher
Frank Jülicher Max Planck Society
David D. Thomas
David D. Thomas University of Minnesota
Susan Ferro-Novick
Susan Ferro-Novick University of California, San Diego
Anna Marie Pyle
Anna Marie Pyle Yale University
Emil Reisler
Emil Reisler University of California, Los Angeles

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