His main research concerns Internal medicine, Cell biology, Endocrinology, Ca2+/calmodulin-dependent protein kinase and Ankyrin. His Internal medicine research includes elements of Mitochondrion and Cardiology. His research integrates issues of Membrane protein and Spectrin in his study of Cell biology.
The various areas that Peter J. Mohler examines in his Endocrinology study include Catecholaminergic polymorphic ventricular tachycardia, Sudden cardiac death and Ion channel. His Ca2+/calmodulin-dependent protein kinase study deals with Angiotensin II intersecting with NADPH oxidase. His work in Ankyrin covers topics such as Sodium channel which are related to areas like Cardiac action potential, Biochemistry, Ventricular tachycardia and Ventricle.
Peter J. Mohler focuses on Internal medicine, Cell biology, Endocrinology, Cardiology and Ankyrin. Internal medicine is closely attributed to Ca2+/calmodulin-dependent protein kinase in his work. His Cell biology research integrates issues from Cytoskeleton, Spectrin, Biochemistry, Ion channel and Membrane protein.
Peter J. Mohler combines subjects such as Sodium-calcium exchanger, Ryanodine receptor, Sudden death and Afterdepolarization with his study of Endocrinology. His Cardiology research is multidisciplinary, incorporating elements of Adenosine and Heart rate. His work deals with themes such as Signal transducing adaptor protein, Neuroscience, Brugada syndrome and Cardiac arrhythmia, which intersect with Ankyrin.
Peter J. Mohler mostly deals with Internal medicine, Cardiology, Cell biology, Heart failure and Atrial fibrillation. His biological study spans a wide range of topics, including Endocrinology, Sodium channel and In vivo. Peter J. Mohler has included themes like Wild type and Kinase in his Endocrinology study.
The study incorporates disciplines such as Titin and Sinoatrial node, Bradycardia, Sinus bradycardia, Heart rate in addition to Cardiology. His Cell biology research includes themes of Cytoskeleton, Spectrin, microRNA, Ion channel and Gene isoform. His study on Cardiac function curve is often connected to Kinetics as part of broader study in Heart failure.
His scientific interests lie mostly in Cell biology, Internal medicine, Spectrin, Heart failure and Ca2+/calmodulin-dependent protein kinase. His Cell biology research is multidisciplinary, incorporating perspectives in Oxidative stress, Ankyrin and In vivo. His Internal medicine study combines topics in areas such as Endocrinology and Cardiology.
In Spectrin, Peter J. Mohler works on issues like Axon, which are connected to NODAL, Ion channel, Action potential and Organelle. His Heart failure study integrates concerns from other disciplines, such as Fibrosis, Blockade, Sodium channel and Electrical conduction system of the heart. His work carried out in the field of Ca2+/calmodulin-dependent protein kinase brings together such families of science as Myocyte, Atrial fibrillation and Action potential duration.
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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
Peter J. Mohler;Jean-Jacques Schott;Anthony O. Gramolini;Keith W. Dilly.
Nature (2003)
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
Jeffrey R. Erickson;Mei ling A. Joiner;Xiaoqun Guan;William Kutschke.
Cell (2008)
FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death
Xander H T Wehrens;Stephan E. Lehnart;Fannie Huang;John A. Vest.
Cell (2003)
Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes
Peter J. Mohler;Ilaria Rivolta;Carlo Napolitano;Guy LeMaillet.
Proceedings of the National Academy of Sciences of the United States of America (2004)
A cardiac arrhythmia syndrome caused by loss of ankyrin-B function
Peter J. Mohler;Igor Splawski;Carlo Napolitano;Georgia Bottelli.
Proceedings of the National Academy of Sciences of the United States of America (2004)
CaMKII determines mitochondrial stress responses in heart
Mei Ling A. Joiner;Olha M. Koval;Jingdong Li;Jingdong Li;B. Julie He.
Nature (2012)
Inherited Arrhythmias A National Heart, Lung, and Blood Institute and Office of Rare Diseases Workshop Consensus Report About the Diagnosis, Phenotyping, Molecular Mechanisms, and Therapeutic Approaches for Primary Cardiomyopathies of Gene Mutations Affecting Ion Channel Function
Stephan E. Lehnart;Michael J. Ackerman;D. Woodrow Benson;Ramon Brugada.
Circulation (2007)
Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts.
Brian J. Hansen;Jichao Zhao;Thomas A. Csepe;Brandon T. Moore.
European Heart Journal (2015)
A βIV-spectrin/CaMKII signaling complex is essential for membrane excitability in mice
Thomas J. Hund;Olha M. Koval;Jingdong Li;Patrick J. Wright.
Journal of Clinical Investigation (2010)
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
B. Julie He;Mei Ling A. Joiner;Madhu V. Singh;Elizabeth D. Luczak.
Nature Medicine (2011)
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