What is he best known for?
The fields of study he is best known for:
Matthew Freeman spends much of his time researching Cell biology, Rhomboid protease, Rhomboid, Intramembrane protease and Signal transduction.
His Cell biology research incorporates elements of Receptor and Genetics.
His Rhomboid protease study deals with Membrane protein intersecting with Growth factor, Proteolysis, Secretory pathway, Endoplasmic reticulum and Golgi apparatus.
The Rhomboid study combines topics in areas such as Protein domain and Somatic cell.
His studies in Intramembrane protease integrate themes in fields like Drosophila Protein and Transmembrane domain.
His study in Signal transduction is interdisciplinary in nature, drawing from both Epidermal growth factor, Ectodomain, ADAM Proteins, Inactive Rhomboid Protein 2 and ADAM17 Protein.
His most cited work include:
- Reiterative Use of the EGF Receptor Triggers Differentiation of All Cell Types in the Drosophila Eye (757 citations)
- Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases. (504 citations)
- Feedback control of intercellular signalling in development (427 citations)
What are the main themes of his work throughout his whole career to date?
Matthew Freeman focuses on Cell biology, Rhomboid, Proteases, Biochemistry and Genetics.
His studies deal with areas such as Receptor, Epidermal growth factor receptor and Drosophila melanogaster as well as Cell biology.
Matthew Freeman works mostly in the field of Receptor, limiting it down to concerns involving Eye development and, occasionally, Cell fate determination.
His research in Rhomboid intersects with topics in Function, Transmembrane domain and Active site.
Matthew Freeman usually deals with Proteases and limits it to topics linked to Serine and Proteolysis.
His work carried out in the field of Signal transduction brings together such families of science as ADAM17 Protein, Immunology, Intracellular and ErbB Receptors.
He most often published in these fields:
- Cell biology (70.00%)
- Rhomboid (33.85%)
- Proteases (26.15%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (70.00%)
- Rhomboid (33.85%)
- Metalloproteinase (4.62%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Rhomboid, Metalloproteinase, Inflammation and Growth factor.
His Cell biology research includes themes of Proteases, In silico, Transmembrane domain and Homology.
In the field of Proteases, his study on Rhomboid protease overlaps with subjects such as PTPN1.
His research in the fields of Intramembrane protease overlaps with other disciplines such as ORAI1.
His Metalloproteinase study integrates concerns from other disciplines, such as Tumor necrosis factor alpha, Receptor, Ligand and In vitro.
His Growth factor course of study focuses on Sheddase and Cytokine, Transmembrane protein, Intracellular and Golgi apparatus.
Between 2017 and 2021, his most popular works were:
- FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex (26 citations)
- The molecular, cellular and pathophysiological roles of iRhom pseudoproteases (17 citations)
- Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation. (12 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cell biology, Membrane protein, Proteases, Growth factor and Rhomboid.
His biological study spans a wide range of topics, including Protease, Function and Tyrosine phosphorylation.
His research in Proteases is mostly focused on Rhomboid protease.
The study incorporates disciplines such as Cell, Cell signaling, Sheddase and Chemical biology in addition to Growth factor.
He combines subjects such as Inflammation and Cell growth with his study of Cell.
His work deals with themes such as Macrophage and Immunology, which intersect with Cell growth.
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