Keith R. Yamamoto mainly focuses on Glucocorticoid receptor, Molecular biology, Cell biology, Transcription and Receptor. His work deals with themes such as Hormone response element and Binding site, which intersect with Glucocorticoid receptor. His Molecular biology research is multidisciplinary, incorporating elements of 5-HT5A receptor and Promoter.
His Cell biology research integrates issues from Regulatory sequence and Nuclear receptor coactivator 2. His Transcription research incorporates themes from Signal transduction and DNA. The concepts of his Receptor study are interwoven with issues in Hsp90 and Transcription factor.
His scientific interests lie mostly in Glucocorticoid receptor, Molecular biology, Cell biology, Biochemistry and Receptor. His research integrates issues of Hormone response element, Regulation of gene expression, Transcription factor and Binding site in his study of Glucocorticoid receptor. His studies in Molecular biology integrate themes in fields like In vitro and Mouse mammary tumor virus, Transcription, Gene, DNA.
Keith R. Yamamoto combines subjects such as Chromatin and Promoter, RNA polymerase II with his study of Transcription. The study incorporates disciplines such as Gene expression, Saccharomyces cerevisiae, Binding domain, Nuclear receptor coactivator 2 and DNA-binding domain in addition to Cell biology. His research in Receptor intersects with topics in Biophysics, Steroid and Response element.
Keith R. Yamamoto mostly deals with Genetics, Glucocorticoid receptor, Gene, Transcription factor and Regulation of gene expression. He focuses mostly in the field of Genetics, narrowing it down to matters related to Computational biology and, in some cases, White paper and National security. Keith R. Yamamoto has included themes like Allosteric regulation and Cell biology in his Glucocorticoid receptor study.
His research investigates the link between Gene and topics such as DNA that cross with problems in Binding site. His Transcription factor study combines topics in areas such as Glucose uptake and Gene expression. Keith R. Yamamoto has researched Regulation of gene expression in several fields, including Beta-catenin, Wnt signaling pathway, Cellular differentiation, Molecular biology and RNA interference.
Keith R. Yamamoto mainly investigates Genetics, Glucocorticoid receptor, Gene, Regulation of gene expression and Biochemistry. His work carried out in the field of Glucocorticoid receptor brings together such families of science as Allosteric regulation, DNA and Cell biology. His DNA study combines topics from a wide range of disciplines, such as Molecular biology, Biophysics, Mutant and Binding site.
His research on Regulation of gene expression frequently links to adjacent areas such as Transcription factor. His Chromatin immunoprecipitation study, which is part of a larger body of work in Biochemistry, is frequently linked to TXNIP, AMPK and Citric acid cycle, bridging the gap between disciplines. While the research belongs to areas of Endocrinology, Keith R. Yamamoto spends his time largely on the problem of Period Circadian Proteins, intersecting his research to questions surrounding Glucocorticoid.
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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA.
B. F. Luisi;W. X. Xu;Z. Otwinowski;L. P. Freedman;L. P. Freedman.
Nature (2003)
Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.
Marc I. Diamond;Jeffrey N. Miner;Steven K. Yoshinaga;Keith R. Yamamoto.
Science (1990)
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.
D. Picard;K. R. Yamamoto.
The EMBO Journal (1987)
Structure and specificity of nuclear receptor-coactivator interactions.
Beatrice D. Darimont;Richard L. Wagner;James W. Apriletti;Michael R. Stallcup.
Genes & Development (1998)
Reduced levels of hsp90 compromise steroid receptor action in vivo
Didier Picard;Bushra Khursheed;Michael J. Garabedian;Marc G. Fortin;Marc G. Fortin.
Nature (1990)
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro.
Katherine A. Jones;Keith R. Yamamoto;Robert Tjian.
Cell (1985)
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
Prescott G. Woodruff;Homer A. Boushey;Gregory M. Dolganov;Chris S. Barker.
Proceedings of the National Academy of Sciences of the United States of America (2007)
A prudent path forward for genomic engineering and germline gene modification
David Baltimore;Paul Berg;Michael Botchan;Dana Carroll.
Science (2015)
Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA
Roger Miesfeld;Sandro Rusconi;Paul J. Godowski;Bonnie A. Maler.
Cell (1986)
The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
Robert M. Nissen;Keith R. Yamamoto.
Genes & Development (2000)
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