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Neuroscience

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107
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41996
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612
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Medicine

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Overview

Luigi F. Agnati is affiliated with the University of Modena and Reggio Emilia in Italy. The scientist's research contributions are primarily in the fields of neuroscience and biochemistry, genetics, and molecular biology, with significant focus on molecular biology and cellular and molecular neuroscience subfields.

Their work repeatedly explores receptor mechanisms and signaling, as well as neuroscience and neuropharmacology research. Other major topics include neuroendocrine regulation and behavior, neural dynamics and brain function, neuroscience of respiration and sleep, neurotransmitter receptor influence on behavior, and nicotinic acetylcholine receptors study.

Several recent papers highlight their focus on the interaction of receptors in the brain, particularly involving dopamine, oxytocin, and adenosine receptors in astrocytes. Notable publications include:

  • Striatal astrocytic A2A-D2 receptor-receptor interactions and their role in neuropsychiatric disorders (2023, Neuropharmacology)
  • Heterodimer of A2A and Oxytocin Receptors Regulating Glutamate Release in Adult Striatal Astrocytes (2022, International Journal of Molecular Sciences)
  • Heteromerization of Dopamine D2 and Oxytocin Receptor in Adult Striatal Astrocytes (2023, International Journal of Molecular Sciences)
  • Intercellular Communication in the Central Nervous System as Deduced by Chemical Neuroanatomy and Quantitative Analysis of Images: Impact on Neuropharmacology (2022, International Journal of Molecular Sciences)
  • Modulation of Neuron and Astrocyte Dopamine Receptors via Receptor-Receptor Interactions (2023, Pharmaceuticals)

Luigi F. Agnati has frequently published in the International Journal of Molecular Sciences, Neuropharmacology, the Italian Journal of Anatomy and Embryology, Pharmaceuticals, and Life. The International Journal of Molecular Sciences features the majority of the scientist's recent work.

Collaborative research is a significant aspect of their work, with frequent co-authorship by Diego Guidolin, Manuela Marcoli, Guido Maura, Chiara Cervetto, and Cinzia Tortorella. These collaborators have jointly contributed to multiple studies within the overlapping domains of neuroscience and molecular biology.

Best Publications

  • Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor.

    Kjell Fuxe;Ann-Charlotte Wikström;Sam Okret;Luigi F. Agnati

  • Astrocytes and Glioblastoma cells release exosomes carrying mtDNA.

    Michele Guescini;Susanna Genedani;Vilberto Stocchi;Luigi Francesco Agnati

  • Intercellular communication in the brain: wiring versus volume transmission.

    Luigi Francesco Agnati;Michele Zoli;I. Stromberg;K. Fuxe

  • Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

    Joëlle A. Hillion;Meritxell Canals;Maria Torvinen;Vicent Casado

  • Targeting adenosine A2A receptors in Parkinson's disease.

    Michael A. Schwarzschild;Luigi Agnati;Kjell Fuxe;Jiang-Fan Chen

  • Glucocorticoid receptor immunoreactivity in monoaminergic neurons of rat brain

    A Härfstrand;K Fuxe;A Cintra;L F Agnati

  • Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization QUALITATIVE AND QUANTITATIVE ASSESSMENT BY FLUORESCENCE AND BIOLUMINESCENCE ENERGY TRANSFER

    Meritxell Canals;Daniel Marcellino;Francesca Fanelli;Francisco Ciruela

  • Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

    Silvia Ginés;Joëlle Hillion;Maria Torvinen;Stèphane Le Crom

  • Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor/Receptor Interactions among Heptahelical Receptors with Examples from the Striatopallidal GABA Neurons

    Luigi F. Agnati;Sergi Ferré;Carme Lluis;Rafael Franco

  • Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia

    Kjell Fuxe;Sergi Ferré;Michele Zoli;Luigi F. Agnati

  • Volume transmission in the CNS and its relevance for neuropsychopharmacology.

    Michele Zoli;Anders Jansson;Eva Syková;Luigi F Agnati

  • Volume Transmission in the Brain: Novel Mechanisms for Neural Transmission

    Kjell Fuxe;Luigi Francesco Agnati

  • Central administration of neuropeptide Y induces hypotension bradypnea and EEG synchronization in the rat.

    Kjell Fuxe;Luigi F. Agnati;Anders Härfstrand;Isabella Zini

  • Detection of heteromerization of more than two proteins by sequential BRET-FRET.

    Paulina Carriba;Gemma Navarro;Francisco Ciruela;Sergi Ferré

  • Localization of glucocorticoid receptor mRNA in the male rat brain by in situ hybridization

    Marie Aronsson;Kjell Fuxe;Yu Dong;Luigi F. Agnati

  • Understanding wiring and volume transmission

    Luigi F Agnati;Diego Guidolin;Michele Guescini;Susanna Genedani

  • Adenosine receptor-dopamine receptor interactions in the basal ganglia and their relevance for brain function.

    Kjell Fuxe;Sergi Ferré;Susanna Genedani;Rafael Franco

  • The discovery of central monoamine neurons gave volume transmission to the wired brain.

    Kjell Fuxe;Annica B. Dahlström;Gösta Jonsson;Daniel Marcellino

  • The emergence of the volume transmission concept

    Michele Zoli;Carla Torri;Rosaria Ferrari;Anders Jansson

  • Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

    Kjell Fuxe;Sergi Ferré;Meritxell Canals;Maria Torvinen

  • Cholecystokinin peptides produce marked reduction of dopamine turnover in discrete areas in the rat brain following intraventricular injection.

    Kjell Fuxe;Kjell Fuxe;Kurt Andersson;Kurt Andersson;Vittorio Locatelli;Vittorio Locatelli;Luigi F. Agnati;Luigi F. Agnati

Frequent Co-Authors

Kjell Fuxe
Kjell Fuxe Karolinska Institute
Michele Zoli
Michele Zoli University of Modena and Reggio Emilia
Dasiel O. Borroto-Escuela
Dasiel O. Borroto-Escuela Karolinska Institute
Diego Guidolin
Diego Guidolin University of Padua
Isabella Zini
Isabella Zini University of Modena and Reggio Emilia
Francisco Ciruela
Francisco Ciruela University of Barcelona
Anders Härfstrand
Anders Härfstrand Karolinska Institute
Rafael Franco
Rafael Franco University of Barcelona
Kurt Andersson
Kurt Andersson Karolinska Institute
Fabio Benfenati
Fabio Benfenati Italian Institute of Technology

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