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Tatsuhiko Kodama

Tatsuhiko Kodama

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
124
Citations
65662
World Ranking
523
National Ranking
21

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Tatsuhiko Kodama is affiliated with the University of Tokyo in Japan. Their research primarily focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. Their work spans several subfields including hepatology, epidemiology, molecular biology, oncology, and cancer research.

The scientist has concentrated on topics related to liver disease diagnosis and treatment, hepatitis C virus research, hepatocellular carcinoma treatment and prognosis, liver disease and transplantation, hepatitis B virus studies, GDF15 and related biomarkers, and pancreatic and hepatic oncology research.

Recent notable publications by Tatsuhiko Kodama include:

  • Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production (2020, Gastroenterology)
  • Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis (2021, Hepatology)
  • Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma (2022, Hepatology)
  • Interleukin-6 Is a Circulating Prognostic Biomarker for Hepatocellular Carcinoma Patients Treated with Combined Immunotherapy (2022, Cancers)
  • ST6GAL1 Is a Novel Serum Biomarker for Lenvatinib-Susceptible FGF19-Driven Hepatocellular Carcinoma (2020, Clinical Cancer Research)

Tatsuhiko Kodama frequently collaborates with other researchers. Common coauthors include:

  • Tetsuo Takehara
  • Hayato Hikita
  • Tomohide Tatsumi
  • Ryotaro Sakamori
  • Yuki Tahata

Their research output appears regularly in a set of core academic journals related to liver and gastrointestinal studies, such as:

  • Hepatology Research
  • Hepatology
  • Journal of Gastroenterology
  • PLoS ONE
  • Journal of Hepatology

Best Publications

  • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.

    Hiroshi Takayanagi;Sunhwa Kim;Takako Koga;Takako Koga;Hiroshi Nishina

  • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

    Mitsuhiro Watanabe;Sander M. Houten;Chikage Mataki;Marcelo A. Christoffolete

  • DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

    Akinori Takaoka;Zhichao Wang;Myoung Kwon Choi;Hideyuki Yanai

  • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

    Kojiro Sato;Ayako Suematsu;Kazuo Okamoto;Akira Yamaguchi

  • Evidence for osteocyte regulation of bone homeostasis through RANKL expression

    Tomoki Nakashima;Mikihito Hayashi;Takanobu Fukunaga;Kosaku Kurata

  • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

    Hiroshi Suzuki;Hiroshi Suzuki;Yukiko Kurihara;Motohiro Takeya;Nobuo Kamada

  • Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

    Tatsuhiko Kodama;Mason Freeman;Mason Freeman;Lucia Rohrer;James Zabrecky

  • Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1.

    Kurihara Y;Kurihara H;Suzuki H;Suzuki H;Kodama T

  • Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

    Noriko Komatsu;Kazuo Okamoto;Shinichiro Sawa;Tomoki Nakashima

  • Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis

    Takako Koga;Masanori Inui;Kazuya Inoue;Sunhwa Kim

  • Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

    Toshiya Tanaka;Joji Yamamoto;Satoshi Iwasaki;Hiroshi Asaba

  • Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.

    Makoto Tachibana;Jun Ueda;Mikiko Fukuda;Naoki Takeda

  • HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

    Hideyuki Yanai;Tatsuma Ban;ZhiChao Wang;Myoung Kwon Choi

  • Osteoprotection by semaphorin 3A

    Mikihito Hayashi;Tomoki Nakashima;Masahiko Taniguchi;Tatsuhiko Kodama

  • Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli

    Katsutoshi Imamura;Naoto Imamachi;Gen Akizuki;Michiko Kumakura

  • Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

    Lucia Rohrer;Mason Freeman;Mason Freeman;Tatsuhiko Kodama;Marsha Penman

  • Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro

    Nick Platt;Hiroshi Suzuki;Yukiko Kurihara;Tatsuhiko Kodama

  • NFAT and Osterix cooperatively regulate bone formation

    Takako Koga;Yuichi Matsui;Masataka Asagiri;Tatsuhiko Kodama

  • Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle

    Tetsuya Kubota;Naoto Kubota;Hiroki Kumagai;Shinichi Yamaguchi

  • Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase

    Y. Terauchi;Y. Tsuji;S. Satoh;H. Minoura

Frequent Co-Authors

Takao Hamakubo
Takao Hamakubo Nippon Medical School
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Juro Sakai
Juro Sakai University of Tokyo
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
Makoto Naito
Makoto Naito Niigata University
Hiroshi Takayanagi
Hiroshi Takayanagi University of Tokyo
Noriko Noguchi
Noriko Noguchi Doshisha University
Yoshio Yazaki
Yoshio Yazaki University of Tokyo
Akira Watanabe
Akira Watanabe Kyoto University
Motohiro Takeya
Motohiro Takeya Kumamoto Health Science University

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