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Hiroyuki Tsuda

Hiroyuki Tsuda

Overview

Hiroyuki Tsuda is affiliated with Nagoya City University in Japan. Their research primarily focuses on the intersection of medicine and materials chemistry, with significant contributions in health, toxicology, mutagenesis, and pulmonary and respiratory medicine. Their work also extends to nutrition and dietetics as well as biomedical engineering.

The scientist's research topics encompass a variety of areas:

  • Nanoparticles: synthesis and applications
  • Air Quality and Health Impacts
  • Occupational and environmental lung diseases
  • Graphene and Nanomaterials Applications
  • Aluminum toxicity and tolerance in plants and animals
  • Carbon Nanotubes in Composites
  • Infant Nutrition and Health

Significant publication venues for this researcher include:

  • Particle and Fibre Toxicology
  • Fundamental Toxicological Sciences
  • Nanomaterials
  • Nutrients
  • Biochemistry and Cell Biology

Frequent coauthors in their body of work include:

  • David B. Alexander
  • William Alexander
  • Akihiko Hirose
  • Aya Naiki-Ito
  • Takamasa Numano

Their key publications cover various studies on nanomaterials and related health impacts:

  • "Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats" (2022) published in Particle and Fibre Toxicology
  • "Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat" (2020) published in Particle and Fibre Toxicology
  • "Lactoferrin Prevents Hepatic Injury and Fibrosis via the Inhibition of NF-κB Signaling in a Rat Non-Alcoholic Steatohepatitis Model" (2021) published in Nutrients
  • "Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study" (2022) published in Particle and Fibre Toxicology
  • "Effects of oral bovine lactoferrin on a mouse model of inflammation associated colon cancer" (2020) published in Biochemistry and Cell Biology

Best Publications

  • Studies on antioxidants: Their carcinogenic and modifying effects on chemical carcinogenesis

    N. Ito;M. Hirose;S. Fukushima;H. Tsuda

  • Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats--an approach for a new medium-term bioassay system.

    Nobuyuki Ito;Hiroyuki Tsuda;Masae Tatematsu;Tadashi Inoue

  • Correlation between Long-Term Survival in Breast Cancer Patients and Amplification of Two Putative Oncogene-Coamplification Units: hst-1/int-2 and c-erbB-2/ear-1

    Tsuda H;Hirohashi S;Shimosato Y;Hirota T

  • Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants.

    Nobuyuki Ito;Shoji Fukushima;Hiroyuki Tsuda

  • Induction of Resistant Hepatocytes as a New Principle for a Possible Short-Term in vivo Test for Carcinogens

    Hiroyuki Tsuda;George Lee;Emmanuel Farber

  • Cancer Prevention by Natural Compounds

    Hiroyuki Tsuda;Yutaka Ohshima;Hiroshi Nomoto;Ken-ichi Fujita

  • Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development.

    Tetsuyuki Takahashi;Nobuo Takasuka;Masaaki Iigo;Masaki Baba

  • Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies.

    Hiroyuki Tsuda;Kazunori Sekine;Ken-Ichi Fujita;Masaaki Ligo

  • Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice

    Atsuya Takagi;Akihiko Hirose;Mitsuru Futakuchi;Hiroyuki Tsuda

  • correlation between histologic grade of malignancy and copy number of c‐erbb‐2 gene in breast carcinoma. A retrospective analysis of 176 cases

    H. Tsuda;S. Hirohashi;Y. Shimosato;T. Hirota

  • Silymarin, a naturally occurring polyphenolic antioxidant flavonoid, inhibits azoxymethane-induced colon carcinogenesis in male F344 rats.

    Hiroyuki Kohno;Takuji Tanaka;Kunihiro Kawabata;Yoshinobu Hirose

  • Activation of intestinal mucosal immunity in tumor-bearing mice by lactoferrin.

    Wen-Ping Wang;Masaaki Iigo;Jun Sato;Kazunori Sekine

  • Orally Administered Lactoferrin Exerts an Antimetastatic Effect and Enhances Production of IL-18 in the Intestinal Epithelium

    Tetsuya Kuhara;Masaaki Iigo;Takehito Itoh;Yoshihiko Ushida

  • Carcinogenic activity of quinoline on rat liver.

    K Hirao;Y Shinohara;H Tsuda;S Fukushima

  • Lactoferrin Inhibits Hepatitis C Virus Viremia in Patients with Chronic Hepatitis C: A Pilot Study

    Katsuaki Tanaka;Masanori Ikeda;Masanori Ikeda;Akito Nozaki;Akito Nozaki;Nobuyuki Kato

  • Biological properties and gene expression associated with metastatic potential of human osteosarcoma

    Tetsuhiro Nakano;Masachika Tani;Yasunori Ishibashi;Kenji Kimura

  • Rapid Bioassay Methods for Carcinogens and Modifiers of Hepatocarcinogenesis

    N Ito;K Imaida;R Hasegawa;H Tsuda

  • Chemopreventive Effects of β‐Carotene, α‐Tocopherol and Five Naturally Occurring Antioxidants on Initiation of Hepatocarcinogenesis by 2‐Amino‐3‐methylimidazo[4,5‐f] qumoline in the Rat

    H Tsuda;N Uehara;Y Iwahori;M Asamoto

  • Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats

    Jiegou Xu;Mitsuru Futakuchi;Hideo Shimizu;David B. Alexander

  • Medium-term bioassay system for detection of carcinogens and modifiers of hepatocarcinogenesis utilizing the GST-P positive liver cell focus as an endpoint marker.

    N Ito;M Tatematsu;R Hasegawa;H Tsuda

Frequent Co-Authors

Fumitaka Kikkawa
Fumitaka Kikkawa Nagoya University
Hiroshi Yamasaki
Hiroshi Yamasaki Kwansei Gakuin University
Malcolm A.S. Moore
Malcolm A.S. Moore Memorial Sloan Kettering Cancer Center
Masae Tatematsu
Masae Tatematsu Nagoya University
Takuji Tanaka
Takuji Tanaka Gifu University
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Hoyoku Nishino
Hoyoku Nishino Kyoto Prefectural University of Medicine
Minako Nagao
Minako Nagao National Cancer Research Institute, UK
Koichi Ohshima
Koichi Ohshima Kurume University
Kazuo Tajima
Kazuo Tajima Kagoshima University

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