World's Best Scientists 2026 revealed!
Keiji Wakabayashi

Keiji Wakabayashi

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
24838
World Ranking
2738
National Ranking
169

Medicine

D-Index
87
Citations
24727
World Ranking
13754
National Ranking
410

Overview

Keiji Wakabayashi is affiliated with the University of Shizuoka in Japan. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a total of 47 and 32 publications respectively in these domains. Within these fields, they have contributed significantly to subfields including Molecular Biology, Oncology, Cancer Research, Health, Toxicology and Mutagenesis, and Physiology.

Their work covers a range of research topics, notably:

  • Gut microbiota and health
  • Carcinogens and Genotoxicity Assessment
  • DNA Repair Mechanisms
  • Colorectal Cancer Screening and Detection
  • Genomics, phytochemicals, and oxidative stress
  • Inflammatory mediators and NSAID effects
  • Gastric Cancer Management and Outcomes

Wakabayashi has published in various scientific venues, with frequent contributions to:

  • Genes and Environment
  • Chemical Research in Toxicology
  • Research Square (Research Square)
  • Scientific Reports
  • BMC Microbiology

Recent papers demonstrate a focus on topics related to colorectal cancer, gut microbiota, and associated carcinogenic factors. Notable recent publications include:

  • Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial, 2021, The Lancet. Gastroenterology & hepatology
  • Association between dietary intake and the prevalence of tumourigenic bacteria in the gut microbiota of middle-aged Japanese adults, 2020, Scientific Reports
  • Mother-to-infant transmission of the carcinogenic colibactin-producing bacteria, 2021, BMC Microbiology
  • Characterization of Colibactin-Producing Escherichia coli Isolated from Japanese Patients with Colorectal Cancer, 2020, Japanese Journal of Infectious Diseases
  • Association of Escherichia coli containing polyketide synthase in the gut microbiota with colorectal neoplasia in Japan, 2021, Cancer Science

Wakabayashi has collaborated frequently with colleagues, including:

  • Michihiro Mutoh
  • Kenji Watanabe
  • Noriyuki Miyoshi
  • Michio Sato
  • Hideki Ishikawa

Best Publications

  • Heterocyclic amines: Mutagens/carcinogens produced during cooking of meat and fish.

    Takashi Sugimura;Keiji Wakabayashi;Hitoshi Nakagama;Minako Nagao

  • Mutagens in surface waters: a review

    Takeshi Ohe;Tetsushi Watanabe;Keiji Wakabayashi

  • Food-derived Mutagens and Carcinogens

    Keiji Wakabayashi;Minako Nagao;Hiroyasu Esumi;Takashi Sugimura

  • The prostate: A target for carcinogenicity of 2-amino-1 -methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods

    Tomoyuki Shirai;Masashi Sano;Seiko Tamano;Satoru Takahashi

  • Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis

    Kouji Watanabe;Toshihiko Kawamori;Seiichi Nakatsugi;Toshihisa Ohta;Toshihisa Ohta

  • Involvement of Prostaglandin E Receptor Subtype EP4 in Colon Carcinogenesis

    Michihiro Mutoh;Kouji Watanabe;Tomohiro Kitamura;Yutaka Shoji

  • Gene mutations and altered gene expression in azoxymethane‐induced colon carcinogenesis in rodents

    Mami Takahashi;Keiji Wakabayashi

  • Quantification of genistein and genistin in soybeans and soybean products

    M. Fukutake;M. Takahashi;K. Ishida;H. Kawamura

  • Mutagenic Principle(s) in Tryptophan and Phenylalanine Pyrolysis Products

    Takashi Sugimura;Takashi Kawachi;Minako Nagao;Takie Yahagi

  • β-Catenin Is Frequently Mutated and Demonstrates Altered Cellular Location in Azoxymethane-induced Rat Colon Tumors

    Mami Takahashi;Kazunori Fukuda;Takashi Sugimura;Keiji Wakabayashi

  • Presence of carcinogenic heterocyclic amines in urine of healthy volunteers eating normal diet, but not of inpatients receiving parenteral alimentation.

    Hirofumi Ushiyama;Keiji Wakabayashi;Misako Hirose;Hajime Itoh

  • Suppression of cyclooxygenase-2 promoter-dependent transcriptional activity in colon cancer cells by chemopreventive agents with a resorcin-type structure

    Michihiro Mutoh;Mami Takahashi;Kazunori Fukuda;Yuko Matsushima-Hibiya

  • Exposure to heterocyclic amines.

    Keiji Wakabayashi;Hirofumi Ushiyama;Makoto Takahashi;Haruo Nukaya

  • Enhancement of colon carcinogenesis by prostaglandin E2 administration

    Toshihiko Kawamori;Naoaki Uchiya;Takashi Sugimura;Keiji Wakabayashi

  • Increased expression of inducible and endothelial constitutive nitric oxide synthases in rat colon tumors induced by azoxymethane.

    Mami Takahashi;Kazunori Fukuda;Takeji Ohata;Takashi Sugimura

  • Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands.

    Naoko Niho;Mami Takahashi;Tomohiro Kitamura;Yutaka Shoji

  • Effects of Soybean Isoflavones on Cell Growth and Apoptosis of the Human Prostatic Cancer Cell Line LNCaP

    Mizuki Onozawa;Kazunori Fukuda;Mikinobu Ohtani;Hideyuki Akaza

  • Dextran sodium sulfate strongly promotes colorectal carcinogenesis in ApcMin/+ mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms

    Takuji Tanaka;Hiroyuki Kohno;Rikako Suzuki;Kazuya Hata

  • Potent Novel Mutagens Produced by Broiling Fish under Normal Conditions

    Hiroshi Kasai;Ziro Yamaizumi;Keiji Wakabayashi;Minako Nagao

  • Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis

    Mami Takahashi;Michihiro Mutoh;Toshihiko Kawamori;Takashi Sugimura

Frequent Co-Authors

Takashi Sugimura
Takashi Sugimura National Cancer Centre
Minako Nagao
Minako Nagao National Cancer Research Institute, UK
Toshiyuki Sakai
Toshiyuki Sakai Kyoto Prefectural University of Medicine
Hitoshi Nakagama
Hitoshi Nakagama National Cancer Research Institute, UK
Takuji Tanaka
Takuji Tanaka Gifu University
Toshikazu Ushijima
Toshikazu Ushijima National Cancer Centre
Masae Tatematsu
Masae Tatematsu Nagoya University
Hiroshi Kasai
Hiroshi Kasai University of Occupational and Environmental Health Japan
Susumu Nishimura
Susumu Nishimura University of Tsukuba
Shuh Narumiya
Shuh Narumiya Kyoto University

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