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Biology and Biochemistry

D-Index
62
Citations
13249
World Ranking
10839
National Ranking
4703

Overview

James G. Granneman is a researcher affiliated with Wayne State University in the United States. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broader disciplines, their research has focused heavily on Molecular Biology, Biochemistry, Physiology, Epidemiology, and Cell Biology.

The main topics covered in their research include:

  • Lipid metabolism and biosynthesis
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Autophagy in Disease and Therapy
  • Photosynthetic Processes and Mechanisms
  • Endoplasmic Reticulum Stress and Disease
  • Lipid Membrane Structure and Behavior

James G. Granneman has contributed to the scientific literature with numerous papers, including recent significant publications such as:

  • Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis, 2021, published in Cell
  • Single cell approaches to address adipose tissue stromal cell heterogeneity, 2020, published in Biochemical Journal
  • STK3/STK4 signalling in adipocytes regulates mitophagy and energy expenditure, 2021, published in Nature Metabolism
  • Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control, 2020, published in Journal of Lipid Research
  • Deconstructing cold-induced brown adipocyte neogenesis in mice, 2022, published in eLife

Their body of work has appeared in a variety of scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Nature Communications
  • Journal of Biological Chemistry
  • eLife

James G. Granneman frequently collaborates with several coauthors, including:

  • Christopher V. Kelly
  • Matthew A. Sanders
  • Elizabeth A. Rondini
  • Emilio P. Mottillo
  • Sonali A. Gandhi

Best Publications

  • In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

    Yun Hee Lee;Anelia P. Petkova;Emilio P. Mottillo;James G. Granneman

  • PER2 controls lipid metabolism by direct regulation of PPARγ

    Benedetto Grimaldi;Marina Maria Bellet;Sayako Katada;Giuseppe Astarita

  • Perilipin Controls Lipolysis by Regulating the Interactions of AB-hydrolase Containing 5 (Abhd5) and Adipose Triglyceride Lipase (Atgl)

    James G. Granneman;Hsiao Ping H Moore;Rukmani Krishnamoorthy;Miloni Rathod

  • Analysis of Lipolytic Protein Trafficking and Interactions in Adipocytes

    James G. Granneman;Hsiao Ping H Moore;Rachel L. Granneman;Andrew S. Greenberg

  • Molecular cloning and expression of the rat beta 3-adrenergic receptor.

    James G. Granneman;Kristine N. Lahners;Archana Chaudhry

  • Metabolic and cellular plasticity in white adipose tissue I: effects of β3-adrenergic receptor activation

    James G. Granneman;Pipeng Li;Zhengxian Zhu;Yuyan Lu

  • Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

    Emilio P. Mottillo;Eric M. Desjardins;Justin D. Crane;Brennan K. Smith

  • Cellular origins of cold-induced brown adipocytes in adult mice

    Yun Hee Lee;Anelia P. Petkova;Anish A. Konkar;James G. Granneman

  • Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling.

    Rayanne B. Burl;Vanesa D. Ramseyer;Elizabeth A. Rondini;Roger Pique-Regi

  • 15O PET Measurement of Blood Flow and Oxygen Consumption in Cold-Activated Human Brown Fat

    Otto Muzik;Thomas J. Mangner;William R. Leonard;Ajay Kumar

  • Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

    Yun Hee Lee;Anelia P. Petkova;James G. Granneman

  • Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism.

    Paola Sacchetti;Todd R. Mitchell;James G. Granneman;Michael J. Bannon

  • Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation

    Emilio P. Mottillo;Priya Balasubramanian;Yun Hee Lee;Changren Weng

  • Adipose tissue plasticity from WAT to BAT and in between.

    Yun Hee Lee;Emilio P. Mottillo;James G. Granneman

  • PPAR δ agonists stimulate oligodendrocyte differentiation in tissue culture

    Inderjeet Saluja;James G. Granneman;Robert P. Skoff

  • Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

    James G. Granneman;Hsiao Ping H Moore;Emilio P. Mottillo;Zhengxian Zhu

  • White adipose tissue contributes to UCP1-independent thermogenesis.

    J. G. Granneman;M. Burnazi;Z. Zhu;L. A. Schwamb

  • Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply

    Emilio P. Mottillo;Ainsley E. Bloch;Todd Leff;James G. Granneman

  • Location, location: protein trafficking and lipolysis in adipocytes

    James G. Granneman;Hsiao Ping H Moore

  • Metabolic and cellular plasticity in white adipose tissue II: role of peroxisome proliferator-activated receptor-α

    Pipeng Li;Zhengxian Zhu;Yuyan Lu;James G. Granneman

Frequent Co-Authors

Michael J. Bannon
Michael J. Bannon Wayne State University
Robert P. Skoff
Robert P. Skoff Wayne State University
Je Kyung Seong
Je Kyung Seong Seoul National University
John H. Postlethwait
John H. Postlethwait University of Oregon
William R. Leonard
William R. Leonard Northwestern University
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University
Gregory R. Steinberg
Gregory R. Steinberg McMaster University
Marina E. Wolf
Marina E. Wolf Oregon Health & Science University
Rodrigo Andrade
Rodrigo Andrade Wayne State University
Kei Sakamoto
Kei Sakamoto University of Copenhagen

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