World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
11240
World Ranking
13255
National Ranking
150

Overview

Je Kyung Seong is affiliated with Seoul National University in South Korea and has contributed extensively to the fields of medicine as well as biochemistry, genetics, and molecular biology. Their research spans a variety of subfields, notably molecular biology, infectious diseases, physiology, epidemiology, and genetics.

The scientist's recent publications cover diverse topics in biomedical research, including cellular heterogeneity in cancer, genetic engineering in model organisms, and microbiota-related physiological effects. Notable recent papers include:

  • Single-cell analysis of gastric pre-cancerous and cancer lesions reveals cell lineage diversity and intratumoral heterogeneity, 2022, npj Precision Oncology
  • Targeted mutagenesis in mouse cells and embryos using an enhanced prime editor, 2021, Genome Biology
  • A resource of targeted mutant mouse lines for 5,061 genes, 2021, Nature Genetics
  • Gut microbiota of the young ameliorates physical fitness of the aged in mice, 2022, Microbiome
  • Ventromedial hypothalamic primary cilia control energy and skeletal homeostasis, 2020, Journal of Clinical Investigation

The following frequent co-authors have collaborated extensively with Je Kyung Seong:

  • Ki Taek Nam
  • Jun Won Park
  • Jun-Young Seo
  • Hun Hwan Kim
  • Gon Sup Kim

Je Kyung Seong's publications often appear in notable scientific venues, with repeated contributions to:

  • Scientific Reports (14 publications)
  • Experimental & Molecular Medicine (11 publications)
  • Laboratory Animal Research (9 publications)
  • International Journal of Molecular Sciences (9 publications)
  • Nature Communications (7 publications)

Their work focuses on several main topics, reflecting a broad interest in metabolism, immunological responses, and the physiological implications of infectious diseases. The primary topics include:

  • Adipose Tissue and Metabolism
  • SARS-CoV-2 and COVID-19 Research
  • Adipokines, Inflammation, and Metabolic Diseases
  • COVID-19 Clinical Research Studies
  • Gut microbiota and health
  • Exercise and Physiological Responses
  • Long-Term Effects of COVID-19

Je Kyung Seong's scientific contributions integrate molecular biology techniques with clinical and physiological studies to explore complex biomedical questions. Their research enhances understanding of disease mechanisms and physiological regulation, particularly in metabolism and immune response contexts.

Best Publications

  • Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models.

    Kyeongdae Kim;Dahee Shim;Jun Seong Lee;Konstantin Zaitsev

  • Inhibitory effect of aqueous extract from the gall of Rhus chinensis on alpha-glucosidase activity and postprandial blood glucose

    Young Jun Shim;Ho Kyung Doo;Se Young Ahn;Yong Suk Kim

  • Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity

    Injae Hwang;Yoon Jeong Park;Yeon-Ran Kim;Yo Na Kim

  • Hepatitis B Virus X Protein Enhances Transcriptional Activity of Hypoxia-inducible Factor-1α through Activation of Mitogen-activated Protein Kinase Pathway

    Young-Gun Yoo;Seung Hyun Oh;Eun Sook Park;Hyeseong Cho

  • Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

    Terrence F Meehan;Nathalie Conte;David B West;Julius O Jacobsen

  • Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low‐density lipoprotein receptor

    Hyunsun Jo;Sung Sik Choe;Kyung Cheul Shin;Hagoon Jang

  • Nuclear receptor PPARγ-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis

    Yoo Jeong Lee;Eun Hee Ko;Ji Eun Kim;Eunha Kim

  • Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells.

    Yoo Yg;Na Ty;Seo Hw;Seong Jk

  • Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma.

    Tae-Young Na;Young Kee Shin;Kyung Jin Roh;Shin-Ae Kang

  • CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3

    Jinho Seo;Eun Woo Lee;Hyerim Sung;Daehyeon Seong

  • Ahnak functions as a tumor suppressor via modulation of TGFβ/Smad signaling pathway.

    I. H. Lee;M. Sohn;H. J. Lim;S. Yoon

  • Sex differences in sympathetic innervation and browning of white adipose tissue of mice

    Sang Nam Kim;Young Suk Jung;Hyun Jung Kwon;Je Kyung Seong

  • PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.

    Terrence F. Meehan;Nathalie Conte;Theodore Goldstein;Giorgio Inghirami

  • RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network

    Kyeongkyu Kim;Kyungjin Boo;Young Suk Yu;Se Kyu Oh

  • Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection.

    Mi Ock Lee;Youn Hee Choi;Eui Cheol Shin;Hyo Jin Kang

  • The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation.

    Violeta Muñoz-Fuentes;Pilar Cacheiro;Terrence F. Meehan;Juan Antonio Aguilar-Pimentel

  • Skeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis

    Seri Choi;Hyeon Ju Jeong;Hyebeen Kim;Dahee Choi

  • Syndecan-2 Functions as a Docking Receptor for Pro-matrix Metalloproteinase-7 in Human Colon Cancer Cells

    Heui Young Ryu;Jiseon Lee;Sanghwa Yang;Haein Park

  • MTA1 is a novel regulator of autophagy that induces tamoxifen resistance in breast cancer cells

    Min-Ho Lee;Dahae Koh;Hyelin Na;Na-Lee Ka

  • Differential Regulation of Estrogen Receptor α Expression in Breast Cancer Cells by Metastasis-Associated Protein 1

    Hyun-Jin Kang;Min-Ho Lee;Hae-Lim Kang;Sung-Hye Kim

Frequent Co-Authors

In Koo Hwang
In Koo Hwang Seoul National University
Moo-Ho Won
Moo-Ho Won Kangwon National University
Colin McKerlie
Colin McKerlie Hospital for Sick Children
Kevin C K Lloyd
Kevin C K Lloyd University of California, Davis
Helen Parkinson
Helen Parkinson European Bioinformatics Institute
Mi-Ock Lee
Mi-Ock Lee Seoul National University
Damian Smedley
Damian Smedley Queen Mary University of London
Paul Flicek
Paul Flicek The Jackson Laboratory
Yann Herault
Yann Herault Institute of Genetics and Molecular and Cellular Biology
Xiang Gao
Xiang Gao Nanjing University

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