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Genetics

D-Index
67
Citations
18853
World Ranking
2516
National Ranking
1125

Overview

Maureen A. Sartor is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with significant contributions in multiple subfields including Molecular Biology, Health, Toxicology and Mutagenesis, Oncology, Otorhinolaryngology, and Genetics.

The scientist's research topics cover a diverse range of areas, including:

  • Epigenetics and DNA Methylation
  • Head and Neck Cancer Studies
  • RNA modifications and cancer
  • Heavy Metal Exposure and Toxicity
  • Effects and risks of endocrine disrupting chemicals
  • Cancer Immunotherapy and Biomarkers
  • Glioma Diagnosis and Treatment

Maureen A. Sartor has contributed extensively to scientific literature, with recent papers that include:

  • "The role of the histone H3 variant CENPA in prostate cancer" (2020) published in Journal of Biological Chemistry
  • "ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization" (2022) published in Cell Reports
  • "Effect of concentration and duration of particulate matter exposure on the transcriptome and DNA methylome of bronchial epithelial cells" (2021) published in Current Zoology
  • "Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma" (2020) published in Journal of Biological Chemistry
  • "Single-Cell Analysis of the Gene Expression Effects of Developmental Lead (Pb) Exposure on the Mouse Hippocampus" (2020) published in Toxicological Sciences

Their frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Oral Oncology
  • Clinical Cancer Research
  • Current Zoology

Regular collaborators in Maureen A. Sartor's work encompass a group of researchers with whom they have co-authored multiple papers. These collaborators are:

  • Tingting Qin
  • Laura S. Rozek
  • Dana C. Dolinoy
  • Nisha J. D'Silva
  • Justin A. Colacino

Throughout their career, Maureen A. Sartor has engaged with interdisciplinary themes at the intersection of molecular biology, cancer research, and environmental health sciences. Their work addresses molecular mechanisms underlying cancer development and progression, the impacts of toxic substances on genetic and epigenetic regulation, and biomarker identification relevant to cancer immunotherapy and disease diagnosis.

Best Publications

  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    Michael S. Lawrence;Carrie Sougnez;Lee Lichtenstein;Kristian Cibulskis

  • ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

    Jaeseok Han;Sung Hoon Back;Junguk Hur;Yu Hsuan Lin

  • MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20

    Xiao Ping Ren;Jinghai Wu;Xiaohong Wang;Maureen A. Sartor

  • Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data

    Alla Karnovsky;Terry Weymouth;Tim Hull;V. Glenn Tarcea

  • Characterization of HPV and host genome interactions in primary head and neck cancers.

    Michael Parfenov;Chandra Sekhar Pedamallu;Nils Gehlenborg;Nils Gehlenborg;Samuel S. Freeman

  • annotatr: genomic regions in context.

    Raymond G Cavalcante;Maureen A Sartor

  • Machine learning approaches and databases for prediction of drug-target interaction: a survey paper.

    Maryam Bagherian;Elyas Sabeti;Kai Wang;Maureen A Sartor

  • Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

    Maureen A Sartor;Craig R Tomlinson;Scott C Wesselkamper;Siva Sivaganesan

  • Genome-Wide DNA Methylation Differences Between Late-Onset Alzheimer's Disease and Cognitively Normal Controls in Human Frontal Cortex

    Kelly M. Bakulski;Dana C. Dolinoy;Maureen A. Sartor;Henry L. Paulson

  • MethylSig: a whole genome DNA methylation analysis pipeline.

    Yongseok Park;Maria E. Figueroa;Laura S. Rozek;Maureen A. Sartor

  • IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.

    Felipe J. Núñez;Flor M. Mendez;Padma Kadiyala;Mahmoud S. Alghamri

  • LRpath: a logistic regression approach for identifying enriched biological groups in gene expression data.

    Maureen A. Sartor;George D. Leikauf;Mario Medvedovic

  • Progression of BRAF -induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

    Jeffrey A Knauf;Maureen A Sartor;Maureen A Sartor;Mario Medvedovic;Emma Lundsmith

  • HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers

    Lada A. Koneva;Yanxiao Zhang;Shama Virani;Pelle B. Hall

  • Genome-wide methylation and expression differences in HPV(+) and HPV(-) squamous cell carcinoma cell lines are consistent with divergent mechanisms of carcinogenesis.

    Maureen A. Sartor;Dana C. Dolinoy;Tamara R. Jones;Justin A. Colacino

  • Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular matrix remodeling.

    Cleo Mesa;Mana Mirza;Norisato Mitsutake;Maureen Sartor

  • ConceptGen: a gene set enrichment and gene set relation mapping tool

    Maureen A. Sartor;Vasudeva Mahavisno;Venkateshwar G. Keshamouni;James D. Cavalcoli

  • The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

    Justin R. Hassler;Donalyn L. Scheuner;Shiyu Wang;Jaeseok Han

  • ChIP-Enrich: gene set enrichment testing for ChIP-seq data

    Ryan P. Welch;Chee Lee;Paul M. Imbriano;Snehal Patil

  • Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation

    Ana Luisa Kadekaro;Sancy Leachman;Renny J. Kavanagh;Viki Swope

Frequent Co-Authors

Laura S. Rozek
Laura S. Rozek Georgetown University
Mario Medvedovic
Mario Medvedovic University of Cincinnati
Thomas E. Carey
Thomas E. Carey University of Michigan–Ann Arbor
Gregory T. Wolf
Gregory T. Wolf University of Michigan–Ann Arbor
George D. Leikauf
George D. Leikauf University of Pittsburgh
Gilbert S. Omenn
Gilbert S. Omenn University of Michigan–Ann Arbor
Alvaro Puga
Alvaro Puga University of Cincinnati Medical Center
Jeremy M. G. Taylor
Jeremy M. G. Taylor University of Michigan–Ann Arbor
Carol R. Bradford
Carol R. Bradford The Ohio State University
Maria E. Figueroa
Maria E. Figueroa University of Miami

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