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Biology and Biochemistry

D-Index
47
Citations
6565
World Ranking
18786
National Ranking
7670

Overview

David S. Phelps is affiliated with Pennsylvania State University in the United States. Their research primarily spans medicine, immunology and microbiology, as well as biochemistry, genetics, and molecular biology. Within these domains, their work often focuses on pulmonary and respiratory medicine, immunology, molecular biology, endocrine and autonomic systems, and health, toxicology, and mutagenesis.

The scientist's body of work covers several key topics, including neonatal respiratory health research, immune response and inflammation, respiratory support and mechanisms, neuroscience of respiration and sleep, air quality and health impacts, epigenetics and DNA methylation, and dietary effects on health.

Recent papers authored or co-authored by David S. Phelps include:

  • Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions (2021, Frontiers in Immunology)
  • Surfactant Protein-A Function: Knowledge Gained From SP-A Knockout Mice (2022, Frontiers in Pediatrics)
  • The Importance of Redox Status in the Frame of Lifestyle Approaches and the Genetics of the Lung Innate Immune Molecules, SP-A1 and SP-A2, on Differential Outcomes of COVID-19 Infection (2020, Antioxidants)
  • Impact of Surfactant Protein-A Variants on Survival in Aged Mice in Response to Klebsiella pneumoniae Infection and Ozone: Serendipity in Action (2020, Microorganisms)
  • Differential Sex-Dependent Regulation of the Alveolar Macrophage miRNome of SP-A2 and co-ex (SP-A1/SP-A2) and Sex Differences Attenuation after 18 h of Ozone Exposure (2020, Antioxidants)

Frequent co-authors in their publications include:

  • Joanna Floros
  • Xuesheng Zhang
  • Vernon M. Chinchilli
  • Judith Weisz
  • Debra A. Shearer

David S. Phelps frequently publishes in journals such as:

  • Antioxidants
  • Frontiers in Immunology
  • Microorganisms
  • Frontiers in Pediatrics
  • JCI Insight

Best Publications

  • Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis

    Moises Selman;Hung Mo Lin;Martha Montaño;Audrey L. Jenkins

  • Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.

    J Floros;R Steinbrink;K Jacobs;D Phelps

  • Localization of surfactant protein synthesis in human lung by in situ hybridization.

    David S. Phelps;Joanna Floros

  • The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production.

    Guirong Wang;Todd M Umstead;David S Phelps;Hamid Al-Mondhiry

  • Localization of pulmonary surfactant proteins using immunohistochemistry and tissue in situ hybridization.

    David S. Phelps;Joanna Floros

  • Surfactant protein A stimulation of inflammatory cytokine and immunoglobulin production.

    S. G. Kremlev;D. S. Phelps

  • Human SP-A protein variants derived from one or both genes stimulate TNF-α production in the THP-1 cell line

    Guirong Wang;David S. Phelps;Todd M. Umstead;Joanna Floros

  • INCREASED RECOVERY OF SURFACTANT PROTEIN A IN AIDS-RELATED PNEUMONIA

    David S. Phelps;Richard M. Rose

  • Surfactant regulation of host defense function in the lung: a question of balance.

    David S. Phelps

  • Surfactant protein A, an innate immune factor, is expressed in the vaginal mucosa and is present in vaginal lavage fluid

    Colin MacNeill;Todd M. Umstead;David S. Phelps;Zhenwu Lin

  • Isolation of a cDNA clone encoding a high molecular weight precursor to a 6-kDa pulmonary surfactant-associated protein.

    K A Jacobs;D S Phelps;R Steinbrink;J Fisch

  • Ultrastructure of lung in surfactant protein B deficiency.

    D. E. deMello;S. Heyman;D. S. Phelps;A. Hamvas

  • Differences in biochemical properties and in biological function between human SP-A1 and SP-A2 variants, and the impact of ozone-induced oxidation.

    Guirong Wang;Sandra R. Bates-Kenney;Jian-Qin Tao;David S. Phelps

  • Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants

    Anatoly N. Mikerov;Todd M. Umstead;Xiaozhuang Gan;Weixiong Huang

  • Surfactant protein A regulates cytokine production in the monocytic cell line THP-1

    Sergey G. Kremlev;Todd M. Umstead;David S. Phelps

  • SP-A1 and SP-A2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages

    Anatoly N. Mikerov;Todd M. Umstead;Weixiong Huang;Wenlei Liu

  • Biosynthesis and in vitro translation of the major surfactant-associated protein from human lung.

    J Floros;D S Phelps;H W Taeusch

  • Factors associated with surfactant treatment response in infants with severe respiratory distress syndrome.

    Anne Charon;H. William Taeusch;Christine Fitzgibbon;Gerald B. Smith

  • An electrophoretic and immunochemical characterization of human surfactant-associated proteins.

    David S. Phelps;H.William Taeusch;H.William Taeusch;Bradley benson;Samuel Hawgood

  • Surfactant protein A2 (SP-A2) variants expressed in CHO cells stimulate phagocytosis of Pseudomonas aeruginosa more than do SP-A1 variants.

    Anatoly N. Mikerov;Guirong Wang;Todd M. Umstead;Mario Zacharatos

Frequent Co-Authors

Joanna Floros
Joanna Floros Pennsylvania State University
Vernon M. Chinchilli
Vernon M. Chinchilli Pennsylvania State University
Moisés Selman
Moisés Selman National Autonomous University of Mexico
Heather P. Harding
Heather P. Harding University of Cambridge
Stella Kourembanas
Stella Kourembanas Boston Children's Hospital
Annie Pardo
Annie Pardo National Autonomous University of Mexico
Samuel Hawgood
Samuel Hawgood University of California, San Francisco
Demetrios Kouretas
Demetrios Kouretas University Of Thessaly
Jay A. Fishman
Jay A. Fishman Harvard University
Michelle A. Williams
Michelle A. Williams Harvard University

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