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Biology and Biochemistry

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87
Citations
25751
World Ranking
2850
National Ranking
1463

Medicine

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88
Citations
26051
World Ranking
13247
National Ranking
6747

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Bruce C. Trapnell is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research primarily focuses on medicine, with significant contributions to pulmonary and respiratory medicine, genetics, epidemiology, infectious diseases, and surgery.

The scientific work of Bruce C. Trapnell covers a variety of topics including neonatal respiratory health research, congenital diaphragmatic hernia studies, inflammatory bowel disease, microscopic colitis, interstitial lung diseases and idiopathic pulmonary fibrosis, COVID-19 clinical research studies, and pulmonary hypertension research and treatments.

Frequent publication venues for this researcher include:

  • Annals of the Rheumatic Diseases
  • Inflammatory Bowel Diseases
  • Journal of Cystic Fibrosis
  • The Lancet Rheumatology
  • New England Journal of Medicine

Bruce C. Trapnell has collaborated regularly with several coauthors, including:

  • Brenna Carey
  • John F. Paolini
  • Ilaria Campo
  • Kristin Hudock
  • M. Imbrogno

Notable published papers include:

  • GM-CSF blockade with mavrilimumab in severe COVID-19 pneumonia and systemic hyperinflammation: a single-centre, prospective cohort study, 2020, The Lancet Rheumatology
  • Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial, 2022, Annals of the Rheumatic Diseases
  • Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis, 2020, New England Journal of Medicine
  • Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial, 2021, The Lancet Rheumatology
  • Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia, 2020, American Journal of Physiology-Lung Cellular and Molecular Physiology

Bruce C. Trapnell has been recognized as a Member of the Association of American Physicians.

Best Publications

  • In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

    Melissa A. Rosenfeld;Kunihiko Yoshimura;Bruce C. Trapnell;Koichi Yoneyama

  • Efficacy and safety of sirolimus in lymphangioleiomyomatosis.

    Francis X. McCormack;Yoshikazu Inoue;Joel Moss;Lianne G. Singer

  • Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy.

    Nanette Mittereder;Keith L. March;Bruce C. Trapnell

  • Pulmonary Alveolar Proteinosis

    Bruce C. Trapnell;Jeffrey A. Whitsett;Koh Nakata

  • GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.

    Yoko Shibata;Pierre Yves Berclaz;Zissis C. Chroneos;Mitsuhiro Yoshida

  • Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

    Subra Kugathasan;Lee A. Denson;Thomas D. Walters;Mi Ok Kim

  • Characteristics of a Large Cohort of Patients with Autoimmune Pulmonary Alveolar Proteinosis in Japan

    Yoshikazu Inoue;Bruce C. Trapnell;Ryushi Tazawa;Toru Arai

  • Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA

    Chin Shyan Chu;Bruce C. Trapnell;Sheila Curristin;Garry R. Cutting

  • Diffuse lung disease in young children: application of a novel classification scheme.

    Gail H. Deutsch;Lisa R. Young;Robin R. Deterding;Leland L. Fan

  • Anaerobic metabolism and quorum sensing by Pseudomonas aeruginosa biofilms in chronically infected cystic fibrosis airways: rethinking antibiotic treatment strategies and drug targets.

    Daniel J Hassett;John Cuppoletti;Bruce Trapnell;Sergei V Lymar

  • Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice.

    Theodore A. G. Smith;Michele G. Mehaffey;Dawn B. Kayda;June M. Saunders

  • Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense.

    Bruce C Trapnell;Jeffrey A Whitsett

  • Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.

    Terence R. Flotte;Bruce C. Trapnell;Margaret Humphries;Brenna Carey

  • GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis.

    Kanji Uchida;David C. Beck;Takashi Yamamoto;Pierre-Yves Berclaz

  • Pulmonary alveolar proteinosis.

    Bruce C Trapnell;Koh Nakata;Francesco Bonella;Ilaria Campo

  • Pulmonary macrophage transplantation therapy

    Takuji Suzuki;Paritha Arumugam;Takuro Sakagami;Nico Lachmann

  • Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA

    Takuji Suzuki;Takuro Sakagami;Bruce K. Rubin;Lawrence M. Nogee

  • Alveolar macrophages release an insulin-like growth factor I-type molecule.

    W N Rom;P Basset;G A Fells;T Nukiwa

  • High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis

    Kanji Uchida;Koh Nakata;Bruce C. Trapnell;Takahiro Terakawa

  • Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis

    Bruce C. Trapnell;Chin-Shyan Chu;Paavo K. Paakko;Tyrone C. Banks

Frequent Co-Authors

jeffrey a whitsett
jeffrey a whitsett Cincinnati Children's Hospital Medical Center
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center
Ronald G. Crystal
Ronald G. Crystal Cornell University
Francis X. McCormack
Francis X. McCormack University of Cincinnati
Jeffrey P. Krischer
Jeffrey P. Krischer University of South Florida
Joel Moss
Joel Moss National Institutes of Health
James M. Wilson
James M. Wilson University of Pennsylvania
Axel Schambach
Axel Schambach Hannover Medical School
Ulrich Costabel
Ulrich Costabel University of Duisburg-Essen
Kevin K. Brown
Kevin K. Brown National Jewish Health

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