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Biology and Biochemistry

D-Index
65
Citations
12121
World Ranking
9362
National Ranking
4130

Overview

Larry L. David is affiliated with Oregon Health & Science University in the United States. Their research spans primarily across the fields of Biochemistry, Genetics and Molecular Biology, with a significant number of publications also related to Medicine. Their work delves into various subfields including Molecular Biology, Physiology, Oncology, Clinical Biochemistry, and Cell Biology.

The scientist's main research topics focus on several key areas:

  • Connexins and lens biology
  • Heat shock proteins research
  • Biochemical effects in animals
  • Advanced Glycation End Products research
  • Ubiquitin and proteasome pathways
  • Molecular Biology Techniques and Applications
  • Cancer-related gene regulation

Larry L. David has contributed to a variety of academic publication venues. The most frequent include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Experimental Eye Research
  • Investigative Ophthalmology & Visual Science
  • Biophysical Journal
  • Blood

Some of the recent papers authored or co-authored by Larry L. David are:

  • Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs, 2020, Blood
  • Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets, 2021, eLife
  • Cumulative deamidations of the major lens protein γS-crystallin increase its aggregation during unfolding and oxidation, 2020, Protein Science
  • p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival, 2020, Journal of Cachexia Sarcopenia and Muscle
  • The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis, 2021, EMBO Reports

Their collaborative network includes frequent co-authors such as Ashok P. Reddy, Phillip A. Wilmarth, Kirsten J. Lampi, John Klimek, and Jessica Minnier, with multiple joint publications particularly with the first two contributors.

Best Publications

  • Ribosomal Protein L23 Activates p53 by Inhibiting MDM2 Function in Response to Ribosomal Perturbation but Not to Translation Inhibition

    Mu Shui Dai;Shelya X. Zeng;Yetao Jin;Xiao Xin Sun

  • Age-related changes in human crystallins determined from comparative analysis of post-translational modifications in young and aged lens: does deamidation contribute to crystallin insolubility?

    P A Wilmarth;S Tanner;S Dasari;S R Nagalla

  • Age-related changes in human lens crystallins identified by two- dimensional electrophoresis and mass spectrometry

    Kirsten J. Lampi;Zhixiang Ma;Stacy R.A. Hanson;Misuyoshi Azuma

  • Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.

    Deanna L. Plubell;Phillip A. Wilmarth;Yuqi Zhao;Alexandra M. Fenton

  • Sequence Analysis of βA3, βB3, and βA4 Crystallins Completes the Identification of the Major Proteins in Young Human Lens

    Kirsten J. Lampi;Zhixiang Ma;Marjorie Shih;Thomas R. Shearer

  • Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age.

    Yoji Ueda;Melinda K Duncan;Larry L David

  • Age-Related Changes in Human Lens Crystallins Identified by HPLC and Mass Spectrometry

    Zhixiang Ma;Stacy R.A. Hanson;Kirsten J. Lampi;Larry L. David

  • Molecular architecture of the chick vestibular hair bundle

    Jung Bum Shin;Jocelyn F. Krey;Ahmed Hassan;Zoltan Metlagel

  • Two-dimensional liquid chromatography study of the human whole saliva proteome.

    Phillip A. Wilmarth;Michael A. Riviere;D. Leif Rustvold;Jeffrey D. Lauten

  • High-throughput identification of proteins and unanticipated sequence modifications using a mass-based alignment algorithm for MS/MS de novo sequencing results.

    Brian C. Searle;Surendra Dasari;Mark Turner;Ashok P. Reddy

  • Role of the Retinal Vascular Endothelial Cell in Ocular Disease

    Arpita S. Bharadwaj;Binoy Appukuttan;Phillip A. Wilmarth;Yuzhen Pan

  • HIF1α Protein Stability Is Increased by Acetylation at Lysine 709

    Hao Geng;Qiong Liu;Changhui Xue;Larry L. David

  • Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway

    David J. Rozansky;Tonya Cornwall;Arohan R. Subramanya;Arohan R. Subramanya;Shaunessy Rogers

  • Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.

    Toru Shibatani;Larry L. David;Ashley L. McCormack;Klaus Frueh

  • Identification of Protein Modifications Using MS/MS de Novo Sequencing and the OpenSea Alignment Algorithm

    Brian C. Searle;Surendra Dasari;Phillip A. Wilmarth;Mark Turner

  • Review of selenite cataract.

    Thomas R. Shearer;Larry L. David;Ruth S. Anderson;Mitsuyoshi Azuma

  • Accurate label-free protein quantitation with high- and low-resolution mass spectrometers.

    Jocelyn F. Krey;Phillip A. Wilmarth;Jung Bum Shin;John Klimek

  • The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.

    Jung Bum Shin;Chantal M. Longo-Guess;Leona H. Gagnon;Katherine W. Saylor

  • Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation.

    L L David;T R Shearer;M Shih

  • Lens β-crystallins: the role of deamidation and related modifications in aging and cataract.

    Kirsten J. Lampi;Phillip A. Wilmarth;Matthew R. Murray;Larry L. David

Frequent Co-Authors

Thomas R. Shearer
Thomas R. Shearer Oregon Health & Science University
Charles T. Roberts
Charles T. Roberts Oregon National Primate Research Center
Owen J. T. McCarty
Owen J. T. McCarty Oregon Health & Science University
Graeme Wistow
Graeme Wistow National Institutes of Health
Surendra Dasari
Surendra Dasari Mayo Clinic
William R. Skach
William R. Skach Cystic Fibrosis Foundation
Hans Peter Bächinger
Hans Peter Bächinger Oregon Health & Science University
Kenneth R. Johnson
Kenneth R. Johnson The Jackson Laboratory
Kevin L. Schey
Kevin L. Schey Vanderbilt University
Hong Ma
Hong Ma Pennsylvania State University

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