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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
11745
World Ranking
11482
National Ranking
4960

Overview

Owen J. T. McCarty is affiliated with Oregon Health & Science University in the United States. Their research primarily focuses on medicine, with significant contributions in hematology, genetics, immunology, cardiology and cardiovascular medicine, and biomedical engineering.

The scientist's work covers a range of topics related to coagulation and thrombosis mechanisms, platelet disorders, and mechanical circulatory support devices, among others. Key research areas include:

  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Blood Coagulation and Thrombosis Mechanisms
  • Platelet Disorders and Treatments
  • Mechanical Circulatory Support Devices
  • Hemophilia Treatment and Research
  • Venous Thromboembolism Diagnosis and Management
  • Mast cells and histamine

The scientist has published extensively in several venues, with frequent publications in:

  • Research and Practice in Thrombosis and Haemostasis (22 publications)
  • Blood (13 publications)
  • Arteriosclerosis Thrombosis and Vascular Biology (12 publications)
  • Journal of Thrombosis and Haemostasis (11 publications)
  • Cellular and Molecular Bioengineering (9 publications)

Frequent collaborators include Joseph J. Shatzel, Cristina Puy, David Gailani, Erik I. Tucker, and Joseph E. Aslan.

Among recent papers authored or co-authored by Owen J. T. McCarty are:

  • "Thrombosis and Bleeding in Extracorporeal Membrane Oxygenation (ECMO) Without Anticoagulation: A Systematic Review" (2020), published in ASAIO Journal
  • "Aspirin and antiplatelet treatments in cancer" (2021), published in Blood
  • "The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial" (2021), published in Blood
  • "Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs" (2020), published in Blood
  • "Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice" (2021), published in Journal of Thrombosis and Haemostasis

Best Publications

  • GPVI and integrin alphaIIb beta3 signaling in platelets

    Steve Watson;Jocelyn Auger;Owen McCarty;Andrew Pearce

  • A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

    Qiufang Cheng;Erik I. Tucker;Meghann S. Pine;India Sisler

  • Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions

    Owen J. T. McCarty;Shaker A. Mousa;Paul F. Bray;Konstantinos Konstantopoulos;Konstantinos Konstantopoulos

  • Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow

    Owen J.T. McCarty;Mark K. Larson;Jocelyn M. Auger;Neena Kalia

  • Ibrutinib-associated bleeding: pathogenesis, management and risk reduction strategies

    Joseph J. Shatzel;Sven R. Olson;Derrick L. Tao;Owen J. T. McCarty

  • Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

    Erik I. Tucker;Ulla M. Marzec;Tara C. White;Sawan Hurst

  • Laminin stimulates spreading of platelets through integrin α6β1–dependent activation of GPVI

    Osamu Inoue;Katsue Suzuki-Inoue;Owen J. T. McCarty;Masaaki Moroi

  • Single molecule characterization of P-selectin/ligand binding.

    William Hanley;Owen McCarty;Sameer Jadhav;Yiider Tseng

  • Factor XII inhibition reduces thrombus formation in a primate thrombosis model

    Anton Matafonov;Anton Matafonov;Philberta Y. Leung;Adam E. Gailani;Stephanie L. Grach

  • Rho GTPases in platelet function.

    Joseph E. Aslan;Owen J. T. McCarty

  • Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

    Asako Itakura;Owen J. T. McCarty

  • Thrombosis and Bleeding in Extracorporeal Membrane Oxygenation (ECMO) Without Anticoagulation: A Systematic Review.

    Sven R Olson;Catherine R Murphree;David Zonies;Andrew D Meyer

  • A physical sciences network characterization of non-tumorigenic and metastatic cells

    David B. Agus;Jenolyn F. Alexander;Wadih Arap;Shashanka Ashili

  • Measurement of single cell refractive index, dry mass, volume, and density using a transillumination microscope.

    Kevin G. Phillips;Steven L. Jacques;Owen J. T. McCarty

  • Microfluidics and coagulation biology.

    Thomas V. Colace;Garth W. Tormoen;Owen J.T. McCarty;Scott L. Diamond

  • Polyphosphate nanoparticles on the platelet surface trigger contact system activation.

    Johan J F Verhoef;Arjan D Barendrecht;Katrin F Nickel;Katrin F Nickel;Kim Dijkxhoorn

  • S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation

    Joseph E. Aslan;Garth W. Tormoen;Cassandra P. Loren;Jiaqing Pang

  • Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells.

    Xia V. Yang;Yajnavalka Banerjee;José A. Fernández;Hiroshi Deguchi

  • Immobilized platelets support human colon carcinoma cell tethering, rolling and firm adhesion under dynamic flow conditions

    Owen McCarty;Konstantinos Konstantopoulos

  • Laminin stimulates spreading of platelets through integrin α6β1-dependent activation of GPVI. Commentary

    Peter J. Newman;Osamu Inoue;Katsue Suzuki-Lnoue;Owen J. T. Mccarty

Frequent Co-Authors

Steve P. Watson
Steve P. Watson University of Birmingham
John H. Griffin
John H. Griffin Scripps Research Institute
Konstantinos Konstantopoulos
Konstantinos Konstantopoulos Johns Hopkins University
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Florea Lupu
Florea Lupu Oklahoma Medical Research Foundation
Larry L. David
Larry L. David Oregon Health & Science University
Zaverio M. Ruggeri
Zaverio M. Ruggeri Scripps Research Institute
Peter Kuhn
Peter Kuhn University of Southern California
Laura M. Machesky
Laura M. Machesky University of Glasgow
Jonathan Chernoff
Jonathan Chernoff Fox Chase Cancer Center

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