Joseph Horwitz

Overview

Best Publications

• Alpha-crystallin can function as a molecular chaperone

  Joseph Horwitz

  2836
  Citations

• The major intrinsic protein (MIP) of the bovine lens fiber membrane : characterization and structure based on cDNA cloning

  Michael B. Gorin;S.Barbara Yancey;Janice Cline;Jean-Paul Revel

  717
  Citations

• Disruption of α3 connexin gene leads to proteolysis and cataractogenesis in mice

  Xiaohua Gong;En Li;George Klier;Qingling Huang

  586
  Citations

• Structural and functional similarities of bovine alpha-crystallin and mouse small heat-shock protein. A family of chaperones.

  K. B. Merck;P. J. T. A. Groenen;C. E. M. Voorter;W. A. De Haard-Hoekman

  546
  Citations

• Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

  Michael P. Bova;Orna Yaron;Qingling Huang;Linlin Ding

  522
  Citations

• Subunit exchange of alphaA-crystallin.

  Michael P. Bova;Lin-Lin Ding;Joseph Horwitz;Bernard K.-K. Fung

  418
  Citations

• The small heat-shock protein, αb-crystallin, has a variable quaternary structure

  Dana A Haley;Joseph Horwitz;Phoebe L Stewart

  412
  Citations

• Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function.

  Arthur Laganowsky;Justin L. P. Benesch;Justin L. P. Benesch;Meytal Landau;Meytal Landau;Linlin Ding

  334
  Citations

• Lens alpha-crystallin: chaperone-like properties.

  Joseph Horwitz;Qing-Ling Huang;Linlin Ding;Michael P. Bova

  317
  Citations

• Fine structure in the near-ultraviolet circular dichroism and absorption spectra of tryptophan derivatives and chymotrypsinogen A at 77 degrees K.

  Strickland Eh;Horwitz J;Billups C

  306
  Citations

• Primary and secondary structure of bovine retinal S antigen (48-kDa protein)

  T Shinohara;B Dietzschold;C M Craft;G Wistow

  286
  Citations

• Lens α-crystallin: Function and structure

  Joseph Horwitz;Michael P Bova;Lin Lin Ding;Dana A Haley;Dana A Haley

  275
  Citations

• Reflectins: The Unusual Proteins of Squid Reflective Tissues

  Wendy J. Crookes;Wendy J. Crookes;Lin-Lin Ding;Lin-Lin Ding;Qing Ling Huang;Qing Ling Huang;Jennifer R. Kimbell;Jennifer R. Kimbell

  257
  Citations

• Interaction of alpha-crystallin with spin-labeled peptides

  Zohreh Toossi Farahbakhsh;Qing-Ling Huang;Lin-Lin Ding;Christian Altenbach

  256
  Citations

• The function of alpha-crystallin in vision☆

  Joseph Horwitz

  256
  Citations

• Near-ultraviolet absorption bands of tryptophan. Studies using indole and 3-methylindole as models.

  Strickland Eh;Horwitz J;Billups C

  217
  Citations

• Mimicking phosphorylation of alphaB-crystallin affects its chaperone activity

  Heath Ecroyd;Sarah Meehan;Joseph Horwitz;J. Andrew Aquilina

  215
  Citations

• Proctor Lecture. The function of alpha-crystallin.

  J Horwitz

  202
  Citations

• Association of the chaperone αB-crystallin with titin in heart muscle

  Belinda Bullard;Charles Ferguson;Ave Minajeva;Mark C. Leake

  201
  Citations

• Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction.

  E Bosch;J Horwitz;D Bok

  199
  Citations