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Genetics

D-Index
75
Citations
20806
World Ranking
1900
National Ranking
871

Overview

Robert S. Sparkes is affiliated with the University of California, Los Angeles in the United States. Their research focuses primarily within the broad discipline of Biochemistry, Genetics and Molecular Biology, with specific attention to Molecular Biology and Cancer Research.

The scientist's work concentrates on topics relating to Cancer, Hypoxia, and Metabolism; Metabolism, Diabetes, and Cancer; as well as Epigenetics and DNA Methylation. These areas reflect an intersection of cellular metabolism and gene regulation processes relevant to disease states such as cancer.

Robert S. Sparkes has published in the Proceedings of the National Academy of Sciences, among other venues. A notable recent publication by this scientist is:

  • Hypoxia induces a glycolytic complex in intestinal epithelial cells independent of HIF-1-driven glycolytic gene expression (2023), Proceedings of the National Academy of Sciences

This paper highlights topics in hypoxia and metabolism, contributing to an understanding of cellular responses under low oxygen conditions that affect metabolic pathways.

Frequent collaborators in their research include:

  • Sarah J. Kierans
  • Raphael R. Fagundes
  • Mykyta I. Malkov
  • Eugène Dillon
  • Albert Smolenski

These coauthors have frequently contributed to the research outputs alongside Robert S. Sparkes, indicating collaborative efforts particularly in molecular biology and cancer-related studies.

Best Publications

  • Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

    Satoshi Tsukada;Douglas C. Saffran;David J. Rawlings;Ornella Parolini;Ornella Parolini

  • Localization of an ataxia-telangiectasia gene to chromosome 11q22–23

    Richard A. Gatti;Izzet Berkel;Elena Boder;Gary Braedt

  • A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis

    Ethylin Wang Jabs;Ulrich Müller;Xiang Li;Liang Ma

  • Regional Assignment of Genes for Human Esterase D and Retinoblastoma to Chromosome Band 13q14

    Robert S. Sparkes;Maryellen C. Sparkes;Miriam G. Wilson;Joseph W. Towner

  • Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene

    William F. Benedict;A. Linn Murphree;Ashutosh Banerjee;Celsa A. Spina

  • D2 and D4 dopamine receptor polymorphisms and personality

    Ernest P. Noble;Tulin Z. Ozkaragoz;Terry L. Ritchie;Xuxian Zhang

  • Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3.

    Cecilia Holm;Todd G. Kirchgessner;Karen L. Svenson;Gudrun Fredrikson

  • Juvenile myoclonic epilepsy (JME) may be linked to the BF and HLA loci on human chromosome 6.

    David A. Greenberg;David A. Greenberg;Antonio V. Delgado-Escueta;Antonio V. Delgado-Escueta;Heidi Widelitz;Robert S. Sparkes

  • An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1)

    HP Koeffler;HP Koeffler;R Billing;R Billing;AJ Lusis;AJ Lusis;R Sparkes;R Sparkes

  • The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships.

    D A Sweetser;E H Birkenmeier;I J Klisak;S Zollman

  • Allelic association of the D2 dopamine receptor gene with cocaine dependence

    Ernest P. Noble;Ernest P. Noble;Kenneth Blum;M.Elena Khalsa;M.Elena Khalsa;Terry Ritchie

  • Ataxia-telangiectasia: an interdisciplinary approach to pathogenesis.

    Richard A. Gatti;Elena Boder;Harry V. Vinters;Robert S. Sparkes

  • D2 dopamine receptor gene and cigarette smoking: A reward gene?

    E.P. Noble;S.T.St. Jeor;T. Ritchie;K. Syndulko

  • Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15.

    Shiuan Chen;Marc J. Besman;Robert S. Sparkes;Susan Zollman

  • Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes

    R S Sparkes;M Simon;V H Cohn;R E Fournier

  • Bone marrow origin of hepatic macrophages (Kupffer cells) in humans.

    Robert Peter Gale;Robert S. Sparkes;David W. Golde

  • D2 dopamine receptor gene and obesity

    Ernest P. Noble;Rudolf E. Noble;Terry Ritchie;Karl Syndulko

  • Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease.

    Nancy C. Lan;Camilla Heinzmann;Andreas Gal;Ivana Klisak

  • Human genes involved in lipolysis of plasma lipoproteins: Mapping of loci for lipoprotein lipase to 8p22 and hepatic lipase to 15q21

    Robert S. Sparkes;Susan Zollman;Ivana Klisak;Todd G. Kirchgessner

  • Familial retinoblastoma and chromosome 13 deletion transmitted via an insertional translocation

    Louise C. Strong;Vincent M. Riccardi;Robert E. Ferrell;Robert S. Sparkes

Frequent Co-Authors

T. K. Mohandas
T. K. Mohandas Dartmouth College
Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles
Antonio V. Delgado-Escueta
Antonio V. Delgado-Escueta University of California, Los Angeles
Kenneth K. Kidd
Kenneth K. Kidd Yale University
Mary L. Marazita
Mary L. Marazita University of Pittsburgh
José M. Serratosa
José M. Serratosa Hospital Universitario Fundación Jiménez Díaz
Richard B. Gaynor
Richard B. Gaynor Eli Lilly (United States)
Margarete Mehrabian
Margarete Mehrabian University of California, Los Angeles
Richard A. Gatti
Richard A. Gatti University of California, Los Angeles
David A. Greenberg
David A. Greenberg Nationwide Children's Hospital

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