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Biology and Biochemistry

D-Index
78
Citations
24665
World Ranking
4502
National Ranking
2188

Overview

Richard B. Gaynor is affiliated with Eli Lilly in the United States and focuses on research in medicine, immunology, and microbiology. Their scientific contributions are primarily situated within subfields such as immunology, oncology, molecular biology, infectious diseases, and radiology, nuclear medicine, and imaging.

Their research topics include:

  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Vaccines and immunoinformatics approaches
  • Cancer Immunotherapy and Biomarkers
  • Monoclonal and Polyclonal Antibodies Research
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology

Frequent co-authors collaborating with Richard B. Gaynor include:

  • Asaf Poran
  • Michael S. Rooney
  • Divya Lenkala
  • Dewi Harjanto
  • Marit M. van Buuren

The scientist's works have been published in various venues, with multiple publications in:

  • Regular and Young Investigator Award Abstracts
  • Cell
  • Cell Reports Methods
  • Nature Medicine
  • Cancer Research

Among the recent papers authored or co-authored by Richard B. Gaynor are:

  • A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer, 2020, Cell
  • Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer, 2022, Cancer Cell
  • A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease, 2024, Cell
  • Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes, 2020, Genome Medicine
  • The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection, 2023, Cell

Best Publications

  • The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β

    Min-Jean Yin;Yumi Yamamoto;Richard B. Gaynor

  • Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.

    S H Ou;F Wu;D Harrich;L F García-Martínez

  • IκB kinases: key regulators of the NF-κB pathway

    Yumi Yamamoto;Richard B Gaynor

  • Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression

    Yumi Yamamoto;Udit N. Verma;Shashi Prajapati;Youn-Tae Kwak

  • Sulindac Inhibits Activation of the NF-κB Pathway

    Yumi Yamamoto;Min-Jean Yin;Keng-Mean Lin;Richard B. Gaynor

  • A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer.

    Patrick A. Ott;Siwen Hu-Lieskovan;Bartosz Chmielowski;Ramaswamy Govindan

  • TAK1 is Critical for IκB Kinase-mediated Activation of the NF-κB Pathway

    Giichi Takaesu;Rama M. Surabhi;Kyu-Jin Park;Jun Ninomiya-Tsuji

  • Cellular transcription factors involved in the regulation of HIV-1 gene expression.

    Richard Gaynor

  • Small Interfering RNAs Directed against β-Catenin Inhibit the in Vitro and in Vivo Growth of Colon Cancer Cells

    Udit N. Verma;Rama M. Surabhi;Aurelia Schmaltieg;Carlos Becerra

  • Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus.

    Joseph A Garcia;F. K. Wu;R. Mitsuyasu;R. B. Gaynor

  • HTLV-I Tax Protein Binds to MEKK1 to Stimulate IκB Kinase Activity and NF-κB Activation

    Min Jean Yin;Lori B. Christerson;Yumi Yamamoto;Youn Tae Kwak

  • Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulation.

    Joseph A Garcia;D. Harrich;E. Soultanakis;F. Wu

  • Role of the TAB2‐related protein TAB3 in IL‐1 and TNF signaling

    Tohru Ishitani;Giichi Takaesu;Jun Ninomiya-Tsuji;Hiroshi Shibuya

  • Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference.

    Noelle Sevilir Williams;Richard B. Gaynor;Shane Scoggin;Udit Verma

  • RNA interference directed against viral and cellular targets inhibits human immunodeficiency Virus Type 1 replication.

    Rama M. Surabhi;Richard B. Gaynor

  • Methylation of SPT5 Regulates Its Interaction with RNA Polymerase II and Transcriptional Elongation Properties

    Youn Tae Kwak;Jun Guo;Shashi Prajapati;Kyu-Jin Park

  • Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes.

    J Alcamí;T Laín de Lera;L Folgueira;M A Pedraza

  • Domains in the SPT5 Protein That Modulate Its Transcriptional Regulatory Properties

    Dmitri Ivanov;Youn Tae Kwak;Jun Guo;Richard B. Gaynor

  • Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat.

    Joseph A Garcia;D. Harrich;L. Pearson;R. Mitsuyasu

  • Heat Shock Protein 27 Association with the IκB Kinase Complex Regulates Tumor Necrosis Factor α-induced NF-κB Activation

    Kyu-Jin Park;Richard B. Gaynor;Youn Tae Kwak

Frequent Co-Authors

Patrick A. Ott
Patrick A. Ott Harvard University
Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles
David S. Sigman
David S. Sigman University of California, Los Angeles
Robert S. Sparkes
Robert S. Sparkes University of California, Los Angeles
Arsène Burny
Arsène Burny Université Libre de Bruxelles
Arnold J. Berk
Arnold J. Berk University of California, Los Angeles
Ramaswamy Govindan
Ramaswamy Govindan Washington University in St. Louis
Kim Margolin
Kim Margolin City Of Hope National Medical Center
Noelle S. Williams
Noelle S. Williams The University of Texas Southwestern Medical Center
William S. Lane
William S. Lane Harvard University

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