D-Index & Metrics Best Publications

David S. Sigman

University of California, Los Angeles
United States

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Chemistry D-index 41 Citations 8,398 91 World Ranking 14305 National Ranking 3797

Biology and Biochemistry D-index 49 Citations 9,364 101 World Ranking 13593 National Ranking 5749

Research.com Recognitions

Awards & Achievements

1972 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study David S. Sigman is best known for:

DNA
Enzyme
DNA polymerase

David S. Sigman performs integrative Gene and Escherichia coli research in his work. He merges many fields, such as Escherichia coli and DNA, in his writings. Borrowing concepts from Molecular biology, David S. Sigman weaves in ideas under DNA. David S. Sigman applies his multidisciplinary studies on Molecular biology and Gene in his research. Biochemistry and Biophysics are two areas of study in which David S. Sigman engages in interdisciplinary work. He combines Biophysics and Biochemistry in his research. David S. Sigman integrates several fields in his works, including Chloroplast and ATP synthase. He merges ATP synthase with Enzyme in his study. In his research, David S. Sigman performs multidisciplinary study on Enzyme and Chloroplast.

His most cited work include:

Oxygen-dependent cleavage of DNA by the 1,10-phenanthroline . cuprous complex. Inhibition of Escherichia coli DNA polymerase I. (442 citations)
The synthesis of enzyme-bound ATP by soluble chloroplast coupling factor 1. (103 citations)

What are the main themes of his work throughout his whole career to date

David S. Sigman performs integrative study on Biochemistry and Computational biology. David S. Sigman performs multidisciplinary study on Computational biology and Gene in his works. David S. Sigman performs multidisciplinary study in Gene and Amino acid in his work. Borrowing concepts from Protein subunit, he weaves in ideas under Amino acid. His Protein subunit study frequently intersects with other fields, such as G alpha subunit. His research combines Fracture (geology) and Paleontology. His Fracture (geology) study frequently draws connections to other fields, such as Cleavage (geology). He combines topics linked to Paleontology with his work on Cleavage (geology). His Escherichia coli study typically links adjacent topics like Lactose permease.

David S. Sigman most often published in these fields:

Biochemistry (81.82%)
Gene (54.55%)
Enzyme (45.45%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Nuclease activity of 1,10-phenanthroline-copper ion

David S. Sigman.
Accounts of Chemical Research (1986)

937 Citations

Oxygen-dependent cleavage of DNA by the 1,10-phenanthroline . cuprous complex. Inhibition of Escherichia coli DNA polymerase I.

D S Sigman;D R Graham;V D'Aurora;A M Stern.
Journal of Biological Chemistry (1979)

671 Citations

Targeted chemical nucleases

David S. Sigman;Thomas W. Bruice;Abhijit Mazumder;Christopher L. Sutton.
Accounts of Chemical Research (1993)

416 Citations

Footprinting DNA-protein complexes in situ following gel retardation assays using 1,10-phenanthroline-copper ion: Escherichia coli RNA polymerase-lac promoter complexes

Michio Kuwabara;David S. Sigman.
Biochemistry (1987)

387 Citations

Cleavage of deoxyribonucleic acid by the 1,10-phenanthroline-cuprous complex. Hydrogen peroxide requirement and primary and secondary structure specificity.

Laura E. Marshall;Daniel R. Graham;Karl A. Reich;David S. Sigman.
Biochemistry (1981)

315 Citations

Polymerase chain reaction amplification of Trypanosoma cruzi kinetoplast minicircle DNA isolated from whole blood lysates: diagnosis of chronic Chagas' disease.

Herbert A. Avila;David S. Sigman;Lee M. Cohen;Robert C. Millikan.
Molecular and Biochemical Parasitology (1991)

307 Citations

Nuclease activity of 1,10-phenanthroline-copper: kinetic mechanism

Theodore B. Thederahn;Michio D. Kuwabara;Teresa A. Larsen;David S. Sigman.
Journal of the American Chemical Society (1989)

279 Citations

Nuclease activity of 1,10-phenanthroline-copper ion. Conformational analysis and footprinting of the lac operon.

Annick Spassky;David S. Sigman.
Biochemistry (1985)

229 Citations

Variable Structures of Fis-DNA Complexes Determined by Flanking DNA – Protein Contacts

Clark Q. Pan;Steven E. Finkel;Sarah E. Cramton;Jin-An Feng.
Journal of Molecular Biology (1996)

228 Citations

Nuclease activity of 1,10-phenanthroline-copper ion: reaction with CGCGAATTCGCG and its complexes with netropsin and EcoRI.

Michio Kuwabara;Chun Yoon;Thomas Goyne;Theodore Thederahn.
Biochemistry (1986)

223 Citations

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Frequent Co-Authors

External Links

Personal Website for David S. Sigman