World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
58
Citations
14754
World Ranking
2071
National Ranking
165

Overview

Yuki Yamaguchi is affiliated with the Tokyo Institute of Technology in Japan and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields, primarily focusing on molecular biology, oncology, genetics, materials chemistry, and surgery.

The scientist's research covers key topics including RNA modifications and cancer, RNA research and splicing, epigenetics and DNA methylation, protein degradation and inhibitors, multiple myeloma research and treatments, genomics and chromatin dynamics, and ubiquitin and proteasome pathways.

Yamaguchi's recent publications include the following papers:

  • Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders, 2022, Chemical Society Reviews
  • ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells, 2020, Nature Chemical Biology
  • Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology, 2021, Cell Chemical Biology
  • Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide, 2020, Scientific Reports
  • The role of Mediator and Little Elongation Complex in transcription termination, 2020, Nature Communications

The frequent co-authors collaborating with Yamaguchi include:

  • Kiyoshi Misawa
  • Daiki Mochizuki
  • Hiroyuki Mineta
  • Ryuji Ishikawa
  • Seiji Hosokawa

Yamaguchi's work has been published in a variety of venues, with notable recurrent appearances in:

  • Practica oto-rhino-laryngologica Suppl
  • Scientific Reports
  • Nature Communications
  • Biological and Pharmaceutical Bulletin
  • Research Square

Best Publications

  • Identification of a Primary Target of Thalidomide Teratogenicity

    Takumi Ito;Hideki Ando;Takayuki Suzuki;Toshihiko Ogura

  • NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation

    Yuki Yamaguchi;Toshiyuki Takagi;Tadashi Wada;Keiichi Yano

  • DSIF, A NOVEL TRANSCRIPTION ELONGATION FACTOR THAT REGULATES RNA POLYMERASE II PROCESSIVITY, IS COMPOSED OF HUMAN SPT4 AND SPT5 HOMOLOGS

    Tadashi Wada;Toshiyuki Takagi;Yuki Yamaguchi;Anwarul Ferdous

  • EVIDENCE THAT P-TEFB ALLEVIATES THE NEGATIVE EFFECT OF DSIF ON RNA POLYMERASE II-DEPENDENT TRANSCRIPTION IN VITRO

    Tadashi Wada;Toshiyuki Takagi;Yuki Yamaguchi;Daisuke Watanabe

  • P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation.

    Tomoko Yamada;Yuki Yamaguchi;Yuki Yamaguchi;Naoto Inukai;Sachiko Okamoto

  • NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

    Chwen Huey Wu;Yuki Yamaguchi;Lawrence R. Benjamin;Maria Horvat-Gordon

  • Mutations of the PAX6 Gene Detected in Patients with a Variety of Optic-Nerve Malformations

    Noriyuki Azuma;Yuki Yamaguchi;Hiroshi Handa;Keiko Tadokoro

  • Evidence that Negative Elongation Factor Represses Transcription Elongation through Binding to a DRB Sensitivity-Inducing Factor/RNA Polymerase II Complex and RNA

    Yuki Yamaguchi;Naoto Inukai;Takashi Narita;Tadashi Wada

  • Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex.

    Takashi Narita;Yuki Yamaguchi;Keiichi Yano;Seiji Sugimoto

  • Mediator requirement for both recruitment and postrecruitment steps in transcription initiation.

    Gang Wang;Michael A. Balamotis;Jennitte L. Stevens;Yuki Yamaguchi

  • Spatial Redox Regulation of a Critical Cysteine Residue of NF-κB in Vivo

    Takeyuki Nishi;Noriaki Shimizu;Masaki Hiramoto;Iwao Sato

  • NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs.

    Takashi Narita;Tetsu M.C. Yung;Junichi Yamamoto;Yasunori Tsuboi

  • A highly purified RNA polymerase II elongation control system.

    Dan B. Renner;Yuki Yamaguchi;Tadashi Wada;Hiroshi Handa

  • Stimulation of RNA polymerase II elongation by hepatitis delta antigen.

    Yuki Yamaguchi;Julija Filipovska;Keiichi Yano;Akiko Furuya

  • Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond.

    Yuki Yamaguchi;Hirotaka Shibata;Hiroshi Handa

  • Structure and function of the human transcription elongation factor DSIF.

    Yuki Yamaguchi;Tadashi Wada;Daisuke Watanabe;Toshiyuki Takagi

  • Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

    Yasuaki Kabe;Takanori Nakane;Ikko Koike;Tatsuya Yamamoto

  • A regulator of transcriptional elongation controls vertebrate neuronal development

    Su Guo;Yuki Yamaguchi;Sarah Schilbach;Tadashi Wada

  • A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity

    Kozue Ando;Satoshi Hirao;Yasuaki Kabe;Yuji Ogura

  • Missense Mutation in the Alternative Splice Region of the PAX6 Gene in Eye Anomalies

    Noriyuki Azuma;Yuki Yamaguchi;Hiroshi Handa;Mutsuko Hayakawa

Frequent Co-Authors

Hiroshi Handa
Hiroshi Handa Tokyo Medical University
Hajime Watanabe
Hajime Watanabe Osaka University
Makoto Suematsu
Makoto Suematsu Keio University
Joan Weliky Conaway
Joan Weliky Conaway The University of Texas Southwestern Medical Center
Arnold J. Berk
Arnold J. Berk University of California, Los Angeles
Ronald C. Conaway
Ronald C. Conaway The University of Texas Southwestern Medical Center
Hisao Ishii
Hisao Ishii Chiba University
Jun-ichi Sawada
Jun-ichi Sawada University of Shizuoka
Shigetsugu Hatakeyama
Shigetsugu Hatakeyama Hokkaido University
Masato Nakafuku
Masato Nakafuku Cincinnati Children's Hospital Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology can open doors to diverse online degree options and career paths in science, healthcare, and education. For those seeking flexible studies at reputable schools, many non profit colleges offer robust online science programs designed for academic rigor and long-term value.

If you have a military background, there are online military friendly colleges that provide tailored student support and flexible course delivery. These programs can help active-duty service members and veterans advance their education and prepare for civilian or research-based roles.

Careers related to molecular biology can also involve social and behavioral sciences. For example, an online masters of social work can lead to roles supporting public health, counseling, or community outreach. Similarly, pursuing a masters in psychology online can prepare you for roles in research, clinical practice, or education.

Consider your professional interests and personal needs when choosing an online degree pathway in molecular biology or a related field.

Best Scientists Citing Yuki Yamaguchi

Trending Scientists

Recently Published Articles