World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10966
World Ranking
15047
National Ranking
6298

Overview

Robert P. Fisher is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a specialized focus on Molecular Biology, Oncology, Biochemistry, Immunology, and Pulmonary and Respiratory Medicine.

The scientist's work covers several main topics, including:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Cancer-related Molecular Pathways
  • Ubiquitin and proteasome pathways
  • Epigenetics and DNA Methylation
  • Protein Degradation and Inhibitors

Recent papers authored or co-authored by Robert P. Fisher include:

  • Dissecting the Pol II transcription cycle and derailing cancer with CDK inhibitors, 2020, Nature Chemical Biology
  • Protein phosphatases in the RNAPII transcription cycle: erasers, sculptors, gatekeepers, and potential drug targets, 2021, Genes & Development
  • Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II, 2020, Nature Communications
  • Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription, 2020, Nucleic Acids Research
  • New connections between ubiquitylation and methylation in the co-transcriptional histone modification network, 2021, Current Genetics

The scientist frequently collaborates with several co-authors, including:

  • Pabitra K. Parua
  • Sampada Kalan
  • Bradley Benjamin
  • Miriam Sansó
  • Daniel O. Pinto

Robert P. Fisher has published regularly in these venues:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Cell
  • Science

Best Publications

  • A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase

    Robert P. Fisher;David O. Morgan

  • Cdk-activating kinase complex is a component of human transcription factor TFIIH

    Ramin Shiekhattar;Fred Mermelstein;Robert P. Fisher;Ronny Drapkin

  • Secrets of a double agent: CDK7 in cell-cycle control and transcription

    Robert P. Fisher

  • Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

    Stéphane Larochelle;Ramon Amat;Kira Glover-Cutter;Miriam Sansó

  • TFIIH-Associated Cdk7 Kinase Functions in Phosphorylation of C-Terminal Domain Ser7 Residues, Promoter-Proximal Pausing, and Termination by RNA Polymerase II

    Kira Glover-Cutter;Stéphane Larochelle;Benjamin Erickson;Chao Zhang

  • Alternative mechanisms of CAK assembly require an assembly factor or an Activating Kinase

    Robert P. Fisher;Pei Jin;Holly M. Chamberlin;David O. Morgan

  • Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells

    Mark E. Burkard;Catherine L. Randall;Stéphane Larochelle;Chao Zhang

  • Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

    Stéphane Larochelle;Karl A. Merrick;Karl A. Merrick;Marie-Emilie Terret;Lara Wohlbold

  • Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity.

    Stéphane Larochelle;Judit Pandur;Robert P. Fisher;Helen K. Salz

  • The Pathogenesis of Esophageal Dysfunction in Scleroderma and Raynaud's Disease

    Sidney Cohen;Robert Fisher;William Lipshutz;Robert Turner

  • Routledge handbook of ecosystem services

    Robert Fisher;R. H. Haines-Young;Marion Potschin;R. Kerry Turner

  • Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2.

    D Desai;H C Wessling;R P Fisher;D O Morgan

  • The structure and substrate specificity of human Cdk12/Cyclin K

    Christian Andreas Bösken;Lucas Farnung;Corinna Hintermair;Miriam Merzel Schachter

  • TFIIH and P-TEFb Coordinate Transcription with Capping Enzyme Recruitment at Specific Genes in Fission Yeast

    Laia Viladevall;Laia Viladevall;Courtney V. St. Amour;Courtney V. St. Amour;Courtney V. St. Amour;Adam Rosebrock;Susanne Schneider

  • T‐loop phosphorylation stabilizes the CDK7–cyclin H–MAT1 complex in vivo and regulates its CTD kinase activity

    Stéphane Larochelle;Jian Chen;Ronald Knights;Judit Pandur

  • p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.

    Arpita Ray;Melissa K. James;Stéphane Larochelle;Robert P. Fisher

  • A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression

    Miriam Merzel Schachter;Karl A. Merrick;Karl A. Merrick;Stéphane Larochelle;Alexander Hirschi

  • A Cdk9–PP1 switch regulates the elongation–termination transition of RNA polymerase II

    Pabitra K. Parua;Gregory T. Booth;Miriam Sansó;Bradley Benjamin

  • Cdk7: a kinase at the core of transcription and in the crosshairs of cancer drug discovery.

    Robert P. Fisher

  • P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.

    Miriam Sansó;Rebecca S. Levin;Jesse J. Lipp;Vivien Ya-Fan Wang

Frequent Co-Authors

Kevan M. Shokat
Kevan M. Shokat University of California, San Francisco
David O. Morgan
David O. Morgan University of California, San Francisco
John T. Lis
John T. Lis Cornell University
Beate Schwer
Beate Schwer Cornell University
Stewart Shuman
Stewart Shuman Memorial Sloan Kettering Cancer Center
Matthias Geyer
Matthias Geyer University of Bonn
Jürg Bähler
Jürg Bähler University College London
Hediye Erdjument-Bromage
Hediye Erdjument-Bromage New York University
Ramin Shiekhattar
Ramin Shiekhattar University of Miami
David Bentley
David Bentley University of Colorado Denver

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