2012 - Fellow of the Royal Society, United Kingdom
David O. Morgan focuses on Cell biology, Cyclin-dependent kinase, Biochemistry, Cyclin-dependent kinase 1 and Kinase. His studies deal with areas such as Anaphase-promoting complex, Mitotic exit, Cdc14 and Cyclin A as well as Cell biology. His Cyclin-dependent kinase study combines topics from a wide range of disciplines, such as Saccharomyces cerevisiae and Cyclin-dependent kinase 2, Protein kinase A, Phosphorylation.
When carried out as part of a general Biochemistry research project, his work on Insulin-like growth factor 2 receptor is frequently linked to work in Nerve growth factor IB, Liver receptor homolog-1, Nuclear receptor co-repressor 1 and ACVR2B, therefore connecting diverse disciplines of study. His study in Kinase is interdisciplinary in nature, drawing from both Cell cycle and Cyclin. His study looks at the relationship between Cell cycle and topics such as Signal transduction, which overlap with Structural biology.
His scientific interests lie mostly in Cell biology, Biochemistry, Cyclin-dependent kinase, Kinase and Phosphorylation. His Cell biology study integrates concerns from other disciplines, such as Cyclin-dependent kinase 1, Cell cycle, Anaphase and Anaphase-promoting complex. He combines subjects such as Gene, Intracellular and Enzyme with his study of Kinase.
His Phosphorylation research incorporates themes from Cell signaling and Signal transduction. As a member of one scientific family, he mostly works in the field of Cyclin A, focusing on Cyclin B and, on occasion, G1/S transition and Mitotic exit. The study incorporates disciplines such as CDK-activating kinase and Cyclin-dependent kinase 7 in addition to Cyclin H.
Cell biology, Biophysics, Genome, Phosphorylation and Cell cycle are his primary areas of study. His biological study focuses on Stem cell. His Phosphorylation research is multidisciplinary, incorporating perspectives in Cyclin-dependent kinase and Kinase.
His work deals with themes such as Cyclin-dependent kinase 1, Gene expression and Mitosis, which intersect with Cyclin-dependent kinase. His study focuses on the intersection of Cell cycle and fields such as In vivo with connections in the field of Ubiquitin and CDC20. His Ubiquitin ligase research entails a greater understanding of Biochemistry.
His primary areas of study are Cell biology, Phosphorylation, Transcription, Severe acute respiratory syndrome coronavirus 2 and Oligomer. David O. Morgan has included themes like Cell cycle, Cell division control protein 4, MCM complex and DNA replication in his Cell biology study. His research integrates issues of Cyclin-dependent kinase, Ubiquitin ligase and Kinase in his study of Phosphorylation.
His Transcription research is multidisciplinary, incorporating elements of RNA, Viral rna, Genome and Protein phosphorylation. In his works, David O. Morgan undertakes multidisciplinary study on Severe acute respiratory syndrome coronavirus 2 and Transcription preinitiation complex.
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Principles of CDK regulation
David O. Morgan.
Cyclin-dependent kinases: engines, clocks, and microprocessors.
David O. Morgan.
Annual Review of Cell and Developmental Biology (1997)
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle
A Koff;A Giordano;D Desai;K Yamashita.
Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose.
Leland Ellis;Eric Clauser;David O. Morgan;Marc Edery.
A chemical switch for inhibitor-sensitive alleles of any protein kinase
Anthony C. Bishop;Jeffrey A. Ubersax;Dejah T. Petsch;Dina P. Matheos.
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Nathanael S. Gray;Lisa Wodicka;Andy-Mark W.H. Thunnissen;Thea C. Norman.
Targets of the cyclin-dependent kinase Cdk1
Jeffrey A. Ubersax;Erika L. Woodbury;Erika L. Woodbury;Phuong N. Quang;Phuong N. Quang;Maria Paraz;Maria Paraz.
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity.
Jianglin He;S. Choe;R. Walker;P. Di Marzio.
Journal of Virology (1995)
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
Yong Gu;Christoph W. Turck;David O. Morgan.
Insulin-like growth factor II receptor as a multifunctional binding protein.
David O. Morgan;David O. Morgan;Jeffrey C. Edman;David N. Standring;Victor A. Fried.
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