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Molecular Biology

D-Index
86
Citations
41052
World Ranking
813
National Ranking
430

Research.com Recognitions

  • 2012 - Fellow of the Royal Society, United Kingdom

Overview

David O. Morgan is affiliated with the University of California, San Francisco in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions in the subfields of molecular biology, cell biology, infectious diseases, ecology, and plant science.

Their recent scholarly output includes works published between 2020 and 2023, reflecting diverse interests in molecular mechanisms and viral biology. Notable papers include:

  • Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions (2020) in Molecular Cell
  • Childhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium (2022) in JAMA Pediatrics
  • Structural basis of human separase regulation by securin and CDK1-cyclin B1 (2021) in Nature
  • Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation (2022) in Journal of Biological Chemistry
  • Assembly of SARS-CoV-2 ribonucleosomes by truncated N∗ variant of the nucleocapsid protein (2023) in Journal of Biological Chemistry

David O. Morgan has collaborated frequently with several researchers, including Christopher R. Carlson, Armin N. Adly, Nairi Hartooni, Jonathan B Asfaha, and Chloe M. Ghent. These partnerships underscore interdisciplinary research efforts in their areas of expertise.

Their publications are often found in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, Nature Communications, Current Biology, and Science Advances, indicating active engagement with high-impact scientific journals.

Their main research topics encompass:

  • Microtubule and mitosis dynamics
  • Bacteriophages and microbial interactions
  • Genomics and chromatin dynamics
  • SARS-CoV-2 and COVID-19 research
  • RNA and protein synthesis mechanisms
  • Advanced biosensing and bioanalysis techniques
  • Ubiquitin and proteasome pathways

David O. Morgan was recognized as a Fellow of the Royal Society, United Kingdom, in 2012, reflecting a milestone in their scientific career.

Best Publications

  • Principles of CDK regulation

    David O. Morgan

  • Cyclin-dependent kinases: engines, clocks, and microprocessors.

    David O. Morgan

  • Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

    Koff A;Giordano A;Desai D;Yamashita K

  • Crystal structure of cyclin-dependent kinase 2.

    De Bondt Hl;Rosenblatt J;Jancarik J;Jones Hd

  • A chemical switch for inhibitor-sensitive alleles of any protein kinase

    Anthony C. Bishop;Jeffrey A. Ubersax;Dejah T. Petsch;Dina P. Matheos

  • Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

    Leland Ellis;Eric Clauser;David O. Morgan;Marc Edery

  • Targets of the cyclin-dependent kinase Cdk1

    Jeffrey A. Ubersax;Erika L. Woodbury;Erika L. Woodbury;Phuong N. Quang;Phuong N. Quang;Maria Paraz;Maria Paraz

  • Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity.

    Jianglin He;S. Choe;R. Walker;P. Di Marzio

  • Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

    Nathanael S. Gray;Lisa Wodicka;Andy-Mark W. H. Thunnissen;Thea C. Norman

  • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit

    Yong Gu;Christoph W. Turck;David O. Morgan

  • Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution

    Liam J. Holt;Brian B. Tuch;Judit Villén;Alexander D. Johnson

  • Insulin-like growth factor II receptor as a multifunctional binding protein.

    David O. Morgan;David O. Morgan;Jeffrey C. Edman;David N. Standring;Victor A. Fried

  • A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase

    Robert P. Fisher;David O. Morgan

  • Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

    Yong Gu;Jody Rosenblatt;David O. Morgan

  • Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

    Sue L. Jaspersen;Julia F. Charles;David O. Morgan

  • Cdk-activating kinase complex is a component of human transcription factor TFIIH

    Ramin Shiekhattar;Fred Mermelstein;Robert P. Fisher;Ronny Drapkin

  • Cyclin-dependent kinases: a family portrait

    Marcos Malumbres;Edward Harlow;Tim Hunt;Tony Hunter

  • Control of mitosis by changes in the subcellular location of cyclin-B1–Cdk1 and Cdc25C

    Catherine G Takizawa;David O Morgan

  • Finishing mitosis, one step at a time

    Matt Sullivan;David O. Morgan

  • Regulation of the APC and the exit from mitosis.

    David O. Morgan

Frequent Co-Authors

Richard A. Roth
Richard A. Roth Stanford University
Alexander D. Johnson
Alexander D. Johnson University of California, San Francisco
Keith Roberts
Keith Roberts John Innes Centre
Bruce Alberts
Bruce Alberts University of California, San Francisco
Peter Walter
Peter Walter University of California, San Francisco
Martin Raff
Martin Raff University College London
Kevan M. Shokat
Kevan M. Shokat University of California, San Francisco
William J. Rutter
William J. Rutter University of California, San Francisco
Robert P. Fisher
Robert P. Fisher Icahn School of Medicine at Mount Sinai
Harold E. Varmus
Harold E. Varmus Cornell University

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