World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
96
Citations
38401
World Ranking
498
National Ranking
231

Genetics

D-Index
93
Citations
31606
World Ranking
973
National Ranking
479

Research.com Recognitions

  • 2011 - Member of the National Academy of Sciences
  • 2007 - Fellow of the American Academy of Arts and Sciences
  • 1976 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1882 - Fellow of the Royal Society of Canada

Overview

Alexander D. Johnson is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Epidemiology, Infectious Diseases, Food Science, and Oncology.

The main topics covered in Johnson's extensive body of work include antifungal resistance and susceptibility, fungal infections and studies, fungal and yeast genetics research, probiotics and fermented foods, Pneumocystis jirovecii pneumonia detection and treatment, gut microbiota and health, and gene regulatory network analysis.

Johnson's recent published papers demonstrate a focus on fungal biology and genetics, biofilm formation, and pathogen adaptation. Notable papers include:

  • Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms (2020, Frontiers in Microbiology)
  • Evolution of the complex transcription network controlling biofilm formation in Candida species (2021, eLife)
  • Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics, and proteomics (2021, Microbiome)
  • Protein-coding changes preceded cis-regulatory gains in a newly evolved transcription circuit (2020, Science)
  • Lineage-specific selection and the evolution of virulence in the Candida clade (2021, Proceedings of the National Academy of Sciences)

Frequent co-authors collaborating with Johnson include:

  • Matthew B. Lohse
  • Clarissa J. Nobile
  • Naomi Ziv
  • Odalys Estefania Lara Garcia
  • Ruby Maini

Johnson has published multiple times in several prominent venues. Their frequent publication venues comprise:

  • Journal of Clinical Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Genetics
  • Frontiers in Microbiology

Throughout their career, Alexander D. Johnson has been recognized with several honors, including being named a Fellow of the American Academy of Arts and Sciences in 2007 and a Member of the National Academy of Sciences in 2011.

Best Publications

  • Candida albicans Biofilms and Human Disease.

    Clarissa J. Nobile;Alexander D. Johnson

  • Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution

    Liam J. Holt;Brian B. Tuch;Judit Villén;Alexander D. Johnson

  • Ssn6-Tup1 is a general repressor of transcription in yeast.

    Cynthia A. Keleher;Michael J. Redd;Janet Schultz;Marian Carlson

  • A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans

    Clarissa J. Nobile;Emily P. Fox;Jeniel E. Nett;Trevor R. Sorrells

  • White-Opaque Switching in Candida albicans Is Controlled by Mating-Type Locus Homeodomain Proteins and Allows Efficient Mating

    Mathew G. Miller;Alexander D. Johnson

  • Control of Filament Formation in Candida albicans by the Transcriptional Repressor TUP1

    Burkhard R. Braun;Alexander D. Johnson

  • Quantitative model for gene regulation by lambda phage repressor

    Gary K. Ackers;Alexander D. Johnson;Madeline A. Shea

  • Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

    Suzanne M Noble;Sarah French;Lisa A Kohn;Victoria Chen

  • Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host.

    Christina M. Hull;Ryan M. Raisner;Alexander D. Johnson

  • Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans.

    Suzanne M. Noble;Alexander D. Johnson

  • Crystal structure of a MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions

    Cynthia Wolberger;Andrew K. Vershon;Beishan Liu;Alexander D. Johnson

  • Development and regulation of single- and multi-species Candida albicans biofilms.

    Matthew B. Lohse;Megha Gulati;Alexander D. Johnson;Clarissa J. Nobile

  • How the λ repressor and cro work

    M. Ptashne;A. Jeffrey;A.D. Johnson;R. Maurer

  • lambda Repressor and cro--components of an efficient molecular switch.

    Alexander D. Johnson;Anthony R. Poteete;Anthony R. Poteete;Gail Lauer;Robert T. Sauer

  • Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity.

    Aaron F Straight;Wenying Shou;Gustave J Dowd;Christoph W Turck

  • A phenotypic profile of the Candida albicans regulatory network.

    Oliver R. Homann;Jeanselle Dea;Suzanne M. Noble;Alexander D. Johnson

  • Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans

    Christina M. Hull;Alexander D. Johnson

  • Turning genes off by Ssn6–Tup1: a conserved system of transcriptional repression in eukaryotes

    Rebecca L Smith;Alexander D Johnson

  • Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains

    Richard J. Bennett;Alexander D. Johnson

  • Identification and Characterization of TUP1-Regulated Genes in Candida albicans

    B R Braun;W S Head;M X Wang;A D Johnson

  • A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

    Alexander D. Johnson;Ira Herskowitz

  • Interactions between DNA-bound repressors govern regulation by the λ phage repressor

    Alexander D. Johnson;Barbara J. Meyer;Mark Ptashne

Frequent Co-Authors

Bruce Alberts
Bruce Alberts University of California, San Francisco
Keith Roberts
Keith Roberts John Innes Centre
Peter Walter
Peter Walter University of California, San Francisco
Martin Raff
Martin Raff University College London
Clarissa J. Nobile
Clarissa J. Nobile University of California, Merced
David O. Morgan
David O. Morgan University of California, San Francisco
Joseph D. Puglisi
Joseph D. Puglisi Stanford University
David R. Andes
David R. Andes University of Wisconsin–Madison
Charles S. Craik
Charles S. Craik University of California, San Francisco
Joseph L. DeRisi
Joseph L. DeRisi University of California, San Francisco

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