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Malcolm Whiteway

Malcolm Whiteway

D-Index & Metrics

Molecular Biology

D-Index
72
Citations
16668
World Ranking
1330
National Ranking
41

Overview

Malcolm Whiteway is affiliated with Concordia University in Canada and has an extensive publication record across several fields related to medicine and molecular biology. Their research primarily addresses antifungal resistance and susceptibility, fungal infections and studies, and fungal and yeast genetics research. Additional topics include peptidase inhibition and analysis, microbial metabolic engineering and bioproduction, polyamine metabolism and applications, and CRISPR and genetic engineering.

They have contributed notably to the following main fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, the scientist has specialized in these subfields:

  • Molecular Biology
  • Infectious Diseases
  • Epidemiology
  • Food Science
  • Pharmacology

They have coauthored numerous papers with frequent collaborators, including:

  • Raha Parvizi Omran
  • Vincent J. J. Martin
  • Vanessa Dumeaux
  • Hui Lu
  • Manjari Shrivastava

Common publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nature Communications
  • PLoS ONE
  • Microbiology Spectrum

Recent papers published by Malcolm Whiteway cover diverse aspects of fungal biology and antifungal strategies. Selected papers include:

  • RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans, 2020, Cell Communication and Signaling
  • Candida albicans targets that potentially synergize with fluconazole, 2021, Critical Reviews in Microbiology
  • Candidiasis: From cutaneous to systemic, new perspectives of potential targets and therapeutic strategies, 2023, Advanced Drug Delivery Reviews
  • Rosemary essential oil and its components 1,8-cineole and α-pinene induce ROS-dependent lethality and ROS-independent virulence inhibition in Candida albicans, 2022, PLoS ONE
  • Screening non-conventional yeasts for acid tolerance and engineering Pichia occidentalis for production of muconic acid, 2023, Nature Communications

Best Publications

  • The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein

    Malcolm Whiteway;Linda Hougan;Daniel Dignard;David Y. Thomas

  • The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components.

    E Leberer;D Dignard;D Harcus;D Y Thomas

  • Morphogenesis in Candida albicans.

    Malcolm Whiteway;Catherine Bachewich

  • Transcription Profiling of Candida albicans Cells Undergoing the Yeast-to-Hyphal Transition

    André Nantel;Daniel Dignard;Catherine Bachewich;Doreen Harcus

  • Roles of the Candida albicans Mitogen-Activated Protein Kinase Homolog, Cek1p, in Hyphal Development and Systemic Candidiasis

    Csilla Csank;Csilla Csank;Klaus Schröppel;Ekkehard Leberer;Doreen Harcus

  • Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans

    Cintia R. C. Rocha;Klaus Schröppel;Doreen Harcus;Anne Marcil

  • A Human-Curated Annotation of the Candida albicans Genome

    Burkhard R Braun;Marco van het Hoog;Christophe d'Enfert;Mikhail Martchenko

  • Superoxide Dismutases in Candida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-induced SOD5 Gene

    Mikhail Martchenko;Anne-Marie Alarco;Doreen Harcus;Malcolm Whiteway;Malcolm Whiteway

  • Stress-induced gene expression in Candida albicans: Absence of a general stress response

    Brice Enjalbert;André Nantel;Malcolm Whiteway

  • A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex

    Marie Evangelista;Bert M. Klebl;Amy H.Y. Tong;Bradley A. Webb

  • Pheromone signalling and polarized morphogenesis in yeast

    Ekkehard Leberer;David Y Thomas;Malcolm Whiteway

  • Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases

    Thomas Leeuw;Cunle Wu;Joseph D. Schrag;Malcolm Whiteway;Malcolm Whiteway

  • Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene.

    Martine Raymond;Philippe Gros;Malcolm Whiteway;David Y. Thomas

  • Pheromone Response in Yeast: Association of Bem1p with Proteins of the MAP Kinase Cascade and Actin

    Thomas Leeuw;Anne Fourest-Lieuvin;Cunle Wu;Janet Chenevert

  • Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans.

    Christopher Askew;Adnane Sellam;Adnane Sellam;Elias Epp;Elias Epp;Hervé Hogues

  • Global Gene Deletion Analysis Exploring Yeast Filamentous Growth

    Owen Ryan;Rebecca S. Shapiro;Christoph F. Kurat;David Mayhew

  • Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p.

    Malcolm S. Whiteway;Cunle Wu;Thomas Leeuw;Karen Clark

  • Candida morphogenesis and host-pathogen interactions.

    Malcolm Whiteway;Ursula Oberholzer

  • Molecular characterization of Ste20p, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae.

    Cunle Wu;Malcolm Whiteway;David Y. Thomas;Ekkehard Leberer

  • Drag&Drop cloning in yeast.

    Gregor Jansen;Cunle Wu;Babette Schade;David Y. Thomas

Frequent Co-Authors

André Nantel
André Nantel National Research Council Canada
David Y. Thomas
David Y. Thomas McGill University
Pierre Côté
Pierre Côté University of Ontario Institute of Technology
Sylvain Meloche
Sylvain Meloche University of Montreal
Carol A. Kumamoto
Carol A. Kumamoto Tufts University
Leah E. Cowen
Leah E. Cowen University of Toronto
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Judith Berman
Judith Berman Tel Aviv University
Matthew Berriman
Matthew Berriman University of Glasgow

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