World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
61
Citations
16320
World Ranking
2967
National Ranking
85

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leah E. Cowen is affiliated with the University of Toronto in Canada. Their research primarily focuses on the field of Medicine with a significant emphasis on Infectious Diseases and Epidemiology. Additional areas of study include Molecular Biology, Plant Science, and Pharmacology.

The scientist's work extensively covers topics related to antifungal resistance and susceptibility, fungal infections and studies, microbial natural products and biosynthesis, plant-microbe interactions and immunity, fungal and yeast genetics research, Pneumocystis jirovecii pneumonia detection and treatment, and probiotics and fermented foods.

Leah E. Cowen has contributed to several recent papers, including:

  • Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond, 2020, Chemical Reviews
  • Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture, 2020, mBio
  • Treatment strategies for cryptococcal infection: challenges, advances and future outlook, 2021, Nature Reviews Microbiology
  • Molecular mechanisms governing antifungal drug resistance, 2023, npj Antimicrobials and Resistance
  • A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase, 2021, Nature Communications

Frequent co-authors in their research include:

  • Nicole Robbins
  • Luke Whitesell
  • Zhongle Liu
  • Emily Puumala
  • Kali R. Iyer

Leah E. Cowen's publications are frequently found in the following venues:

  • Nature Communications
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • mSphere

In 2020, Leah E. Cowen was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi.

    Leah E. Cowen;Susan Lindquist

  • Regulatory Circuitry Governing Fungal Development, Drug Resistance, and Disease

    Rebecca S. Shapiro;Nicole Robbins;Leah E. Cowen

  • Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond.

    Yunjin Lee;Emily Puumala;Nicole Robbins;Leah E Cowen

  • Mechanisms of Antifungal Drug Resistance

    Leah E. Cowen;Dominique Sanglard;Susan J. Howard;P. David Rogers

  • Antifungal drug resistance: evolution, mechanisms and impact.

    Nicole M Revie;Kali R Iyer;Nicole Robbins;Leah E Cowen

  • Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture.

    Matthew C. Fisher;Sarah J. Gurr;Christina A. Cuomo;David S. Blehert

  • Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

    Leah E. Cowen;Sheena D. Singh;Julia R. Köhler;Cathy Collins

  • Molecular Evolution of Antifungal Drug Resistance.

    Nicole Robbins;Tavia Caplan;Leah E Cowen

  • Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.

    Sheena D. Singh;Nicole Robbins;Aimee K. Zaas;Wiley A. Schell

  • The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype.

    Leah E. Cowen

  • Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance.

    Anna M. Selmecki;Keely Dulmage;Leah E. Cowen;James B. Anderson

  • Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance

    Leah E. Cowen;William J. Steinbach

  • PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

    Shantelle L. LaFayette;Cathy Collins;Aimee K. Zaas;Wiley A. Schell

  • Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling.

    Rebecca S. Shapiro;Priya Uppuluri;Aimee K. Zaas;Cathy Collins

  • Hsp90 governs dispersion and drug resistance of fungal biofilms.

    Nicole Robbins;Priya Uppuluri;Jeniel Nett;Ranjith Rajendran

  • Treatment strategies for cryptococcal infection: challenges, advances and future outlook

    Kali R. Iyer;Nicole M. Revie;Ci Fu;Nicole Robbins

  • Evolution of drug resistance in experimental populations of Candida albicans.

    Leah E. Cowen;Dominique Sanglard;David Calabrese;Caroline Sirjusingh

  • Antifungal Drugs: The Current Armamentarium and Development of New Agents

    Nicole Robbins;Gerard D. Wright;Leah E. Cowen

  • Global Gene Deletion Analysis Exploring Yeast Filamentous Growth

    Owen Ryan;Rebecca S. Shapiro;Christoph F. Kurat;David Mayhew

  • Global analysis of fungal morphology exposes mechanisms of host cell escape

    Teresa R. O’Meara;Amanda O. Veri;Troy Ketela;Bo Jiang

  • MINIREVIEWS Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance

    Leah E. Cowen;William J. Steinbach

Frequent Co-Authors

Joseph Heitman
Joseph Heitman Duke University
James B. Anderson
James B. Anderson University of Toronto
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Linda M. Kohn
Linda M. Kohn University of Toronto
Christina A. Cuomo
Christina A. Cuomo Broad Institute
Corey Nislow
Corey Nislow University of British Columbia
Charles Boone
Charles Boone University of Toronto
Dominique Sanglard
Dominique Sanglard University of Lausanne
John R. Perfect
John R. Perfect Duke University

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