Dominique Sanglard mainly focuses on Candida albicans, Microbiology, Corpus albicans, Gene and Fluconazole. His Candida albicans study incorporates themes from Biochemistry, Saccharomyces cerevisiae, Yeast and Mutant. His studies deal with areas such as Efflux and ATP-binding cassette transporter as well as Microbiology.
His Corpus albicans study combines topics in areas such as Fungal protein and Virulence. His study with Gene involves better knowledge in Genetics. In his study, Cytochrome P450 is strongly linked to Lanosterol, which falls under the umbrella field of Fluconazole.
His primary scientific interests are in Microbiology, Candida albicans, Corpus albicans, Gene and Biochemistry. His study focuses on the intersection of Microbiology and fields such as Virulence with connections in the field of Wild type. His Candida albicans research incorporates elements of ATP-binding cassette transporter, Mutant, Fungal protein, Efflux and In vivo.
His research in Corpus albicans is mostly concerned with Oropharyngeal Candidiasis. His work in Gene covers topics such as Molecular biology which are related to areas like Nucleic acid sequence and Locus. His study explores the link between Drug resistance and topics such as Antifungal drug that cross with problems in Pharmacology.
His primary areas of investigation include Microbiology, Candida albicans, Corpus albicans, Gene and Genetics. His research integrates issues of In vitro and In vivo in his study of Microbiology. His Candida albicans research is multidisciplinary, incorporating elements of Biochemistry, Echinocandin, Flavones and Cell biology.
His work on Oropharyngeal Candidiasis as part of his general Corpus albicans study is frequently connected to Oral mucosa, thereby bridging the divide between different branches of science. His Yarrowia, Virulence and Transcriptional regulation study in the realm of Gene connects with subjects such as Fitness function and Set. His research investigates the link between Fluconazole and topics such as Human pathogen that cross with problems in Drug resistance and Intensive care.
His main research concerns Microbiology, Candida albicans, In vivo, Corpus albicans and In vitro. Dominique Sanglard combines subjects such as Mutation and Opportunistic pathogen with his study of Microbiology. Candida albicans and Oral mucosa are two areas of study in which Dominique Sanglard engages in interdisciplinary work.
Dominique Sanglard interconnects Amphotericin B, Antifungal, Medical mycology and Fungal biofilm in the investigation of issues within In vivo. He works in the field of Corpus albicans, focusing on Oropharyngeal Candidiasis in particular. His research in Fluconazole intersects with topics in Galleria mellonella, Allele and Candida tropicalis.
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Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences
D. Sanglard;Frank Christopher Odds.
Lancet Infectious Diseases (2002)
Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.
D Sanglard;K Kuchler;F Ischer;J L Pagani.
Antimicrobial Agents and Chemotherapy (1995)
Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.
Dominique Sanglard;Françoise Ischer;Michel Monod;Jacques Bille.
Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents
Dominique Sanglard;Françoise Ischer;Luc Koymans;Jacques Bille.
Antimicrobial Agents and Chemotherapy (1998)
Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients
Sofia Perea;José L. López-Ribot;William R. Kirkpatrick;Robert K. McAtee.
Antimicrobial Agents and Chemotherapy (2001)
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.
D Sanglard;F Ischer;M Monod;J Bille.
Antimicrobial Agents and Chemotherapy (1996)
Worldwide emergence of resistance to antifungal drugs challenges human health and food security.
Matthew C. Fisher;Nichola J. Hawkins;Dominique Sanglard;Sarah J. Gurr;Sarah J. Gurr.
The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.
Dominique Sanglard;Françoise Ischer;David Calabrese;Paul A. Majcherczyk.
Antimicrobial Agents and Chemotherapy (1999)
Antifungal drug resistance in pathogenic fungi.
H Vanden Bossche;F Dromer;I Improvisi;M Lozano-Chiu.
Medical Mycology (1998)
A Mutation in Tac1p, a Transcription Factor Regulating CDR1 and CDR2, Is Coupled With Loss of Heterozygosity at Chromosome 5 to Mediate Antifungal Resistance in Candida albicans
Alix T. Coste;Vincent Turner;Françoise Ischer;Joachim Morschhäuser.
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