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Dominique Sanglard

Dominique Sanglard

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Microbiology
Switzerland
2025

D-Index & Metrics

Microbiology

D-Index
94
Citations
30795
World Ranking
572
National Ranking
12

Research.com Recognitions

  • 2025 - Research.com Microbiology in Switzerland Leader Award
  • 2022 - Research.com Microbiology in Switzerland Leader Award

Overview

Dominique Sanglard is affiliated with the University of Lausanne in Switzerland. Their research primarily focuses on the field of Medicine, with a significant number of publications related to Infectious Diseases, Epidemiology, and Molecular Biology. Additional subfields include Food Science and Pharmacology.

The scientist's work addresses various topics, notably:

  • Antifungal resistance and susceptibility
  • Fungal infections and studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Probiotics and fermented foods
  • Peptidase inhibition and analysis
  • Fungal biology and applications
  • Plant pathogens and fungal diseases

Dominique Sanglard has published extensively, with frequent publications in journals such as:

  • Antimicrobial Agents and Chemotherapy
  • Journal of Fungi
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Microbiology
  • Microbiology Spectrum

Among recent papers authored or co-authored by them are:

  • Camphor and Eucalyptol-Anticandidal Spectrum, Antivirulence Effect, Efflux Pumps Interference and Cytotoxicity, 2021, International Journal of Molecular Sciences
  • Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland, 2020, Infection
  • Flavones, Flavonols, and Glycosylated Derivatives-Impact on Candida albicans Growth and Virulence, Expression of CDR1 and ERG11, Cytotoxicity, 2020, Pharmaceuticals
  • Novel ERG11 and TAC1b Mutations Associated with Azole Resistance in Candida auris, 2021, Antimicrobial Agents and Chemotherapy
  • Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation, 2022, PLoS Pathogens

The scientist frequently collaborates with other researchers, including:

  • Frédéric Lamoth
  • Alix T. Coste
  • Jizhou Li
  • Van Du T. Tran
  • Christophe d'Enfert

Best Publications

  • Worldwide emergence of resistance to antifungal drugs challenges human health and food security

    Matthew C. Fisher;Nichola J. Hawkins;Dominique Sanglard;Sarah J. Gurr;Sarah J. Gurr

  • Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

    D. Sanglard;Frank Christopher Odds

  • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.

    D Sanglard;K Kuchler;F Ischer;J L Pagani

  • Azole antifungal resistance in Candida albicans and emerging non-albicans Candida Species

    Sarah G. Whaley;Elizabeth L. Berkow;Jeffrey M. Rybak;Andrew T. Nishimoto

  • Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.

    Dominique Sanglard;Françoise Ischer;Michel Monod;Jacques Bille

  • Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

    Dominique Sanglard;Françoise Ischer;Luc Koymans;Jacques Bille

  • Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated from Human Immunodeficiency Virus-Infected Patients

    Sofia Perea;José L. López-Ribot;William R. Kirkpatrick;Robert K. McAtee

  • Mechanisms of Antifungal Drug Resistance

    Leah E. Cowen;Dominique Sanglard;Susan J. Howard;P. David Rogers

  • Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.

    D Sanglard;F Ischer;M Monod;J Bille

  • Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents

    Dominique Sanglard;Françoise Ischer;Tania Parkinson;Derek Falconer

  • A Mutation in Tac1p, a Transcription Factor Regulating CDR1 and CDR2, Is Coupled With Loss of Heterozygosity at Chromosome 5 to Mediate Antifungal Resistance in Candida albicans

    Alix T. Coste;Vincent Turner;Françoise Ischer;Joachim Morschhäuser

  • TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

    Alix T. Coste;Mahir Karababa;Françoise Ischer;Jacques Bille

  • Emerging Threats in Antifungal-Resistant Fungal Pathogens.

    Dominique Sanglard

  • The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.

    Dominique Sanglard;Françoise Ischer;David Calabrese;Paul A. Majcherczyk

  • Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence

    Dominique Sanglard;Françoise Ischer;Oscar Marchetti;José Entenza

  • A Human-Curated Annotation of the Candida albicans Genome

    Burkhard R Braun;Marco van het Hoog;Christophe d'Enfert;Mikhail Martchenko

  • Antifungal drug resistance in pathogenic fungi.

    H Vanden Bossche;F Dromer;I Improvisi;M Lozano-Chiu

  • Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.

    Bernhard Hube;Dominique Sanglard;Frank C. Odds;Daniela Hess

  • Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates

    Alix Coste;Anna Selmecki;Anja Forche;Dorothée Diogo

  • A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

    D. Sanglard;B. Hube;M. Monod;F. C. Odds

Frequent Co-Authors

Jacques Bille
Jacques Bille University of Lausanne
Michel Monod
Michel Monod University Hospital of Lausanne
Maurizio Sanguinetti
Maurizio Sanguinetti Catholic University of the Sacred Heart
Bernhard Hube
Bernhard Hube Leibniz Association
Brunella Posteraro
Brunella Posteraro Catholic University of the Sacred Heart
Rajendra Prasad
Rajendra Prasad Amity University
Armin Fiechter
Armin Fiechter ETH Zurich
Christophe d'Enfert
Christophe d'Enfert Institut Pasteur
Frank C. Odds
Frank C. Odds University of Aberdeen

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