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Microbiology

D-Index
52
Citations
9911
World Ranking
4200
National Ranking
1627

Overview

P. David Rogers is affiliated with St. Jude Children's Research Hospital in the United States. Their research spans primarily within the field of Medicine, with significant contributions focused on Infectious Diseases, Epidemiology, and Pharmacology.

Their notable recent papers include:

  • Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris, 2020, mBio
  • In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris, 2021, Clinical Microbiology and Infection
  • The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris, 2022, Current Opinion in Microbiology
  • Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance, 2021, Microbiology Spectrum
  • Mechanisms of triazole resistance in Aspergillus fumigatus, 2020, Environmental Microbiology

Their research topics reflect a focus on fungal pathogens and antifungal resistance, with main topics including:

  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Fungal Biology and Applications
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Fungal and yeast genetics research
  • Infectious Diseases and Mycology
  • Microbial Natural Products and Biosynthesis

P. David Rogers has published frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antimicrobial Agents and Chemotherapy
  • Clinical Microbiology and Infection
  • mSphere
  • mBio

They have collaborated extensively with several co-authors, including:

  • Jeffrey M. Rybak
  • Christina A. Cuomo
  • Katherine S. Barker
  • Josie E. Parker
  • Laura A. Doorley

The body of work by P. David Rogers addresses mechanisms of antifungal drug resistance with a particular focus on emerging fungal pathogens such as Candida auris. Their work covers molecular genetics, clinical resistance patterns, and pharmacological aspects, contributing to understanding the challenges faced in managing fungal infections.

Best Publications

  • Azole antifungal resistance in Candida albicans and emerging non-albicans Candida Species

    Sarah G. Whaley;Elizabeth L. Berkow;Jeffrey M. Rybak;Andrew T. Nishimoto

  • Mechanisms of Antifungal Drug Resistance

    Leah E. Cowen;Dominique Sanglard;Susan J. Howard;P. David Rogers

  • Genome-Wide Expression Profiling of the Response to Azole, Polyene, Echinocandin, and Pyrimidine Antifungal Agents in Candida albicans

    Teresa T. Liu;Robin E. B. Lee;Katherine S. Barker;Richard E. Lee

  • The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans.

    Joachim Morschhäuser;Katherine S Barker;Teresa T Liu;Julia Blaß-Warmuth

  • Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains.

    Nico Dunkel;Julia Blaß;P. David Rogers;Joachim Morschhäuser

  • A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.

    Nico Dunkel;Teresa T. Liu;Katherine S. Barker;Ramin Homayouni

  • A Review of Pneumococcal Vaccines: Current Polysaccharide Vaccine Recommendations and Future Protein Antigens

    Calvin C Daniels;P David Rogers;Chasity M Shelton

  • Contribution of Clinically Derived Mutations in ERG11 to Azole Resistance in Candida albicans

    Stephanie A. Flowers;Brendan Colón;Sarah G. Whaley;Mary A. Schuler

  • Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies.

    John-Paul Vermitsky;Kelly D. Earhart;W. Lamar Smith;Ramin Homayouni

  • Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans

    Stephanie A. Flowers;Katherine S. Barker;Elizabeth L. Berkow;Geoffrey Toner

  • Genome-wide Expression Profiling of the Response to Polyene, Pyrimidine, Azole, and Echinocandin Antifungal Agents in Saccharomyces cerevisiae

    Ameeta K. Agarwal;P.David Rogers;Scott R. Baerson;Melissa R. Jacob

  • Genome-Wide Expression Profile Analysis Reveals Coordinately Regulated Genes Associated with Stepwise Acquisition of Azole Resistance in Candida albicans Clinical Isolates

    P. David Rogers;Katherine S. Barker

  • Voriconazole: A New Triazole Antifungal Agent

    Margaret M Pearson;P David Rogers;John D Cleary;Stanley W Chapman

  • Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris.

    Jeffrey M. Rybak;José F. Muñoz;Katherine S. Barker;Josie E. Parker

  • An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans.

    Clemens J. Heilmann;Sabrina Schneider;Katherine S. Barker;P. David Rogers

  • Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans

    Katherine S. Barker;Sarah Crisp;Nathan P Wiederhold;Russell E. Lewis

  • Genome-wide expression and location analyses of the Candida albicans Tac1p regulon.

    Teresa T. Liu;Sadri Znaidi;Katherine S. Barker;Lijing Xu

  • Regulation of Efflux Pump Expression and Drug Resistance by the Transcription Factors Mrr1, Upc2, and Cap1 in Candida albicans

    Sabrina Schubert;Katherine S. Barker;Sadri Znaidi;Sabrina Schneider

  • Abrogation of Triazole Resistance upon Deletion of CDR1 in a Clinical Isolate of Candida auris.

    Jeffrey M. Rybak;Laura A. Doorley;Andrew T. Nishimoto;Katherine S. Barker

  • Evaluation of Differential Gene Expression in Fluconazole-Susceptible and -Resistant Isolates of Candida albicans by cDNA Microarray Analysis

    P. David Rogers;Katherine S. Barker

  • The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris

    Unknown

Frequent Co-Authors

Joachim Morschhäuser
Joachim Morschhäuser University of Würzburg
Nathan P. Wiederhold
Nathan P. Wiederhold The University of Texas Health Science Center at San Antonio
Steven L. Kelly
Steven L. Kelly Swansea University
Brian M. Peters
Brian M. Peters University of Tennessee Health Science Center
Theodore C. White
Theodore C. White University of Missouri–Kansas City
Aaron P. Mitchell
Aaron P. Mitchell University of Georgia
Russell E. Lewis
Russell E. Lewis University of Padua
Scott G. Filler
Scott G. Filler University of California, Los Angeles
Larry S. McDaniel
Larry S. McDaniel University of Mississippi Medical Center
Christina A. Cuomo
Christina A. Cuomo Broad Institute

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