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Microbiology

D-Index
97
Citations
28744
World Ranking
488
National Ranking
227

Overview

David S. Perlin is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily focuses on medicine, with a specialization in infectious diseases and a considerable emphasis on antifungal resistance and susceptibility. Their work covers several subfields, including epidemiology, molecular biology, pharmacology, and plant science.

The scientist's frequent research topics include:

  • Antifungal resistance and susceptibility
  • Fungal infections and studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Antimicrobial resistance in Staphylococcus
  • Fungal and yeast genetics research
  • Infectious diseases and mycology
  • Plant pathogens and fungal diseases

David S. Perlin has published extensively in notable venues. Common publication forums include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Fungi
  • Antimicrobial Agents and Chemotherapy
  • Medical Mycology
  • Studies in Mycology

Their collaborations often involve several recurrent coauthors, such as:

  • Amir Arastehfar
  • Erika Shor
  • Macit İlkit
  • Farnaz Daneshnia
  • Rocio Garcia-Rubio

Among recent publications by or involving David S. Perlin are the following works:

  • COVID-19 Associated Pulmonary Aspergillosis (CAPA)-From Immunology to Treatment, 2020, Journal of Fungi
  • Drug-Resistant Fungi: An Emerging Challenge Threatening Our Limited Antifungal Armamentarium, 2020, Antibiotics
  • A naturally inspired antibiotic to target multidrug-resistant pathogens, 2022, Nature
  • Aspergillus fumigatus and aspergillosis: From basics to clinics, 2021, Studies in Mycology
  • Studying severe long COVID to understand post-infectious disorders beyond COVID-19, 2022, Nature Medicine

The concentration of David S. Perlin's work aligns closely with topics in infectious diseases, fungal biology, and antimicrobial resistance, drawing on multidisciplinary approaches that span clinical and molecular studies. Their scholarship contributes to understanding both fungal pathogens and broader antimicrobial resistance mechanisms.

Best Publications

  • The global problem of antifungal resistance: prevalence, mechanisms, and management

    David S Perlin;Riina Rautemaa-Richardson;Ana Alastruey-Izquierdo

  • Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

    Barbara D. Alexander;Melissa D. Johnson;Christopher D. Pfeiffer;Cristina Jiménez-Ortigosa

  • Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure

    Susan J. Howard;Dasa Cerar;Michael J. Anderson;Ahmed Albarrag

  • Resistance to echinocandin-class antifungal drugs

    David S. Perlin

  • Mechanisms of Antifungal Drug Resistance

    Leah E. Cowen;Dominique Sanglard;Susan J. Howard;P. David Rogers

  • A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009-17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance.

    Anuradha Chowdhary;Anupam Prakash;Cheshta Sharma;Milena Kordalewska

  • Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

    S. Park;R. Kelly;J. Nielsen Kahn;J. Robles

  • Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens.

    Bradley M. Hover;Seong Hwan Kim;Micah Katz;Zachary Charlop-Powers

  • A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.

    Guillermo Garcia-Effron;Santosh K. Katiyar;Steven Park;Thomas D. Edlind

  • COVID-19 associated pulmonary aspergillosis (CAPA)—from immunology to treatment

    Amir Arastehfar;Agostinho Carvalho;Frank L. van de Veerdonk;Jeffrey D. Jenks

  • High-frequency Triazole Resistance Found In Nonculturable Aspergillus fumigatus from Lungs of Patients with Chronic Fungal Disease

    David W. Denning;Steven Park;Cornelia Lass-Florl;Marcin G. Fraczek;Marcin G. Fraczek

  • Clinical breakpoints for the echinocandins and Candida revisited: Integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria

    M.A. Pfaller;D.J. Diekema;D. Andes;M.C. Arendrup

  • Echinocandin Resistance in Candida

    David S. Perlin

  • Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β-d-Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

    Guillermo Garcia-Effron;Samuel Lee;Steven Park;John D. Cleary

  • Echinocandin resistance: an emerging clinical problem?

    Maiken Cavling Arendrup;David S. Perlin

  • Mechanisms of echinocandin antifungal drug resistance.

    David S. Perlin

  • Current perspectives on echinocandin class drugs

    David S Perlin

  • Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole

    Adriana M. Nascimento;Gustavo H. Goldman;Steven Park;Salvatore A. E. Marras

  • Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints.

    Guillermo Garcia-Effron;Steven Park;David S. Perlin

  • A naturally inspired antibiotic to target multidrug-resistant pathogens

    Unknown

  • Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.

    Kelley R. Healey;Yanan Zhao;Winder B. Perez;Shawn R. Lockhart

  • Assessing Resistance to the Echinocandin Antifungal Drug Caspofungin in Candida albicans by Profiling Mutations in FKS1

    Sergey V. Balashov;Steven Park;David S. Perlin;David S. Perlin

Frequent Co-Authors

Steven Park
Steven Park Rutgers, The State University of New Jersey
Guillermo Garcia-Effron
Guillermo Garcia-Effron National University of the Littoral
Maiken Cavling Arendrup
Maiken Cavling Arendrup Statens Serum Institut
James E. Haber
James E. Haber Brandeis University
Thomas J. Walsh
Thomas J. Walsh Weill Cornell Medicine
Dimitrios P. Kontoyiannis
Dimitrios P. Kontoyiannis The University of Texas MD Anderson Cancer Center
David W. Denning
David W. Denning University of Manchester
Macit Ilkit
Macit Ilkit Cukurova University
Teun Boekhout
Teun Boekhout University of Amsterdam
Emmanuel Roilides
Emmanuel Roilides Aristotle University of Thessaloniki

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