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Biology and Biochemistry

D-Index
71
Citations
16225
World Ranking
6731
National Ranking
56

Overview

Karl Kuchler is affiliated with the Medical University of Vienna in Austria. They have contributed extensively to research in several interconnected fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology.

Their research spans several subfields including epidemiology, infectious diseases, molecular biology, oncology, and immunology. The main topics covered in their work include antifungal resistance and susceptibility, fungal infections and studies, drug transport and resistance mechanisms, Pneumocystis jirovecii pneumonia detection and treatment, trace elements in health, peptidase inhibition and analysis, and iron metabolism and disorders.

Karl Kuchler has a record of publications in various scientific venues, with a notable frequency in:

  • Cell Reports
  • mSphere
  • bioRxiv (Cold Spring Harbor Laboratory)
  • FEBS Letters
  • PLoS Pathogens

Their frequent coauthors include Sabrina Jenull, Trinh Phan-Canh, Raju Shivarathri, Neeraj Chauhan, and Manju Chauhan.

Some recent papers authored or co-authored by Karl Kuchler are:

  • Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection, 2020, Cell Host & Microbe
  • The Multifaceted Roles of Mast Cells in Immune Homeostasis, Infections and Cancers, 2022, International Journal of Molecular Sciences
  • Multidrug Resistance in Mammals and Fungi-From MDR to PDR: A Rocky Road from Atomic Structures to Transport Mechanisms, 2021, International Journal of Molecular Sciences
  • The Two-Component Response Regulator Ssk1 and the Mitogen-Activated Protein Kinase Hog1 Control Antifungal Drug Resistance and Cell Wall Architecture of Candida auris, 2020, mSphere
  • Picky ABCG5/G8 and promiscuous ABCG2 - a tale of fatty diets and drug toxicity, 2020, FEBS Letters

Best Publications

  • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.

    D Sanglard;K Kuchler;F Ischer;J L Pagani

  • Detoxification of the Fusarium Mycotoxin Deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana

    Brigitte Poppenberger;Franz Berthiller;Doris Lucyshyn;Tobias Sieberer

  • Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

    K Kuchler;R E Sterne;J Thorner

  • The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast

    Peter Piper;Yannick Mahé;Suzanne Thompson;Rudy Pandjaitan

  • ABC proteins : from bacteria to man

    I. Barry Holland;Susan P. C. Cole;Karl Kuchler;Christopher F. Higgins

  • Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance.

    Bettina E Bauer;Hubert Wolfger;Karl Kuchler

  • Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance.

    Ingrid E. Frohner;Christelle Bourgeois;Kristina Yatsyk;Olivia Majer

  • Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance.

    P H Bissinger;K Kuchler

  • Yeast ABC transporters – A tale of sex, stress, drugs and aging

    Helmut Jungwirth;Karl Kuchler

  • Global Gene Deletion Analysis Exploring Yeast Filamentous Growth

    Owen Ryan;Rebecca S. Shapiro;Christoph F. Kurat;David Mayhew

  • The Arabidopsis thaliana ABC transporter AtMRP5 controls root development and stomata movement

    Nicola Gaedeke;Markus Klein;Uener Kolukisaoglu;Cyrille Forestier

  • Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae.

    K Kuchler;G Daum;F Paltauf

  • The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling.

    Cristina Reinoso-Martín;Christoph Schüller;Manuela Schuetzer-Muehlbauer;Karl Kuchler

  • Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

    Richard K. Plemper;Ralf Egner;Karl Kuchler;Dieter H. Wolf

  • The Facultative Intracellular Pathogen Candida glabrata Subverts Macrophage Cytokine Production and Phagolysosome Maturation

    Katja Seider;Sascha Brunke;Lydia Schild;Nadja Jablonowski

  • Analysis of the cDNA for phospholipase A2 from honeybee venom glands. The deduced amino acid sequence reveals homology to the corresponding vertebrate enzymes.

    Karl Kuchler;Michael Gmachl;Manfred J. Sippl;Günther Kreil

  • Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes.

    Tobias Schwarzmüller;Biao Ma;Ekkehard Hiller;Fabian Istel

  • The Saccharomyces cerevisiae weak-acid-inducible ABC transporter Pdr12 transports fluorescein and preservative anions from the cytosol by an energy-dependent mechanism.

    Caroline D. Holyoak;Danielle Bracey;Peter W. Piper;Karl Kuchler

  • Global Phenotypic Analysis and Transcriptional Profiling Defines the Weak Acid Stress Response Regulon in Saccharomyces cerevisiae

    Christoph Schüller;Yasmine M. Mamnun;Mehdi Mollapour;Gerd Krapf

  • Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections

    Olivia Majer;Christelle Bourgeois;Florian Zwolanek;Caroline Lassnig

Frequent Co-Authors

Bernhard Hube
Bernhard Hube Leibniz Association
Jeremy Thorner
Jeremy Thorner University of California, Berkeley
Franz Berthiller
Franz Berthiller BOKU University
Peter W. Piper
Peter W. Piper University of Sheffield
Josef Glössl
Josef Glössl BOKU University
Rudolf Krska
Rudolf Krska BOKU University
Rainer Schuhmacher
Rainer Schuhmacher BOKU University
Gustav Ammerer
Gustav Ammerer University of Vienna
Christophe d'Enfert
Christophe d'Enfert Institut Pasteur
Ilse D. Jacobsen
Ilse D. Jacobsen Leibniz Association

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