World's Best Scientists 2026 revealed!

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Microbiology

D-Index
56
Citations
15975
World Ranking
3659
National Ranking
1436

Overview

Raymond P. Donnelly is affiliated with the US Food and Drug Administration in the United States. Their research primarily spans the field of medicine, with a focus on several subfields including epidemiology, immunology, infectious diseases, oncology, and molecular biology.

The scientist's research topics cover a diverse range of subjects, particularly related to viral infections and immune system response. Key topics include:

  • Influenza Virus Research Studies
  • Interferon and Immune Responses
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory Viral Infections Research
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction
  • Viral Infections and Immunology Research

Prominent papers authored by or associated with Donnelly include:

  • Weak Induction of Interferon Expression by Severe Acute Respiratory Syndrome Coronavirus 2 Supports Clinical Trials of Interferon-λ to Treat Early Coronavirus Disease 2019 (2020, Clinical Infectious Diseases)
  • Impact of Baloxavir Resistance-Associated Substitutions on Influenza Virus Growth and Drug Susceptibility (2023, Journal of Virology)
  • Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations (2021, Pharmaceutical Research)
  • Pleiotropic Effects of Influenza H1, H3, and B Baloxavir-Resistant Substitutions on Replication, Sensitivity to Baloxavir, and Interferon Expression (2022, Antimicrobial Agents and Chemotherapy)
  • Laninamivir-Interferon Lambda 1 Combination Treatment Promotes Resistance by Influenza A Virus More Rapidly than Laninamivir Alone (2020, Antimicrobial Agents and Chemotherapy)

The scientist frequently publishes in journals such as:

  • Journal of Interferon & Cytokine Research
  • Antimicrobial Agents and Chemotherapy
  • Clinical Infectious Diseases
  • Journal of Virology
  • Pharmaceutical Research

Key frequent coauthors collaborating with Donnelly include:

  • Natalia A. Ilyushina
  • Brady T. Hickerson
  • Harold Dickensheets
  • Faruk Sheikh
  • Simone E. Adams

The scientist's work integrates clinical and molecular approaches to infectious diseases, with particular attention to the immune responses triggered by viral agents such as influenza viruses and SARS-CoV-2. This focus is reflected in the publication venues and research topics, which emphasize immune function, antiviral resistance mechanisms, and therapeutic formulation stability.

Best Publications

  • IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

    Sergei V. Kotenko;Grant Gallagher;Vitaliy V. Baurin;Anita Lewis-Antes

  • A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

    Ludmila Prokunina-Olsson;Brian Muchmore;Wei Tang;Ruth M Pfeiffer

  • Identification of the Functional Interleukin-22 (IL-22) Receptor Complex THE IL-10R2 CHAIN (IL-10Rβ) IS A COMMON CHAIN OF BOTH THE IL-10 AND IL-22 (IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR, IL-TIF) RECEPTOR COMPLEXES

    Sergei V. Kotenko;Lara S. Izotova;Olga V. Mirochnitchenko;Elena Esterova

  • Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

    Xavier Michelet;Xavier Michelet;Lydia Dyck;Andrew Hogan;Roisin M Loftus

  • Interleukin-10 Inhibits Expression of Both Interferon – and Interferon γ– Induced Genes by Suppressing Tyrosine Phosphorylation of STAT1

    Satoshi Ito;Parswa Ansari;Minoru Sakatsume;Harold Dickensheets

  • The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes.

    Raymond P. Donnelly;Harold Dickensheets;David S. Finbloom

  • Interferon-lambda: a new addition to an old family.

    Raymond P. Donnelly;Sergei V. Kotenko

  • mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function

    Raymond P. Donnelly;Róisín M. Loftus;Sinéad E. Keating;Kevin T. Liou

  • The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

    Raymond P. Donnelly;Faruk Sheikh;Sergei V. Kotenko;Harold Dickensheets

  • Identification, Cloning, and Characterization of a Novel Soluble Receptor That Binds IL-22 and Neutralizes Its Activity

    Sergei V. Kotenko;Lara S. Izotova;Olga V. Mirochnitchenko;Elena Esterova

  • Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

    G Gallagher;H Dickensheets;J Eskdale;LS Izotova

  • Srebp-controlled glucose metabolism is essential for NK cell functional responses

    Nadine Assmann;Katie L O'Brien;Raymond P Donnelly;Lydia Dyck

  • Characterization of the mouse IFN-λ ligand-receptor system: IFN-λs exhibit antitumor activity against B16 melanoma

    Ahmed Lasfar;Anita Lewis-Antes;Sergey V Smirnov;Shubha Anantha

  • General nature of the STAT3-activated anti-inflammatory response

    Karim C. El Kasmi;Jeff Holst;Maryaline Coffre;Lisa Mielke

  • Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression

    Harold L. Dickensheets;Chandrasekar Venkataraman;Ulrike Schindler;Raymond P. Donnelly

  • Inhibition of IL-10 expression by IFN-gamma up-regulates transcription of TNF-alpha in human monocytes.

    R P Donnelly;S L Freeman;M P Hayes

  • Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.

    Faruk Sheikh;Vitaliy V. Baurin;Anita Lewis-Antes;Nital K. Shah

  • Production of IL-10 by human natural killer cells stimulated with IL-2 and/or IL-12.

    Priti T. Mehrotra;Raymond P. Donnelly;Susan Wong;Hirokazu Kanegane

  • IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity.

    Stephen G. Maher;Faruk Sheikh;Anthony J. Scarzello;Ana L. Romero-Weaver

  • Type III IFNs Are Produced by and Stimulate Human Plasmacytoid Dendritic Cells

    Zhiwei Yin;Jihong Dai;Jing Deng;Faruk Sheikh

  • Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain

    Thirumalai R Ramalingam;John T Pesce;Faruk Sheikh;Allen W Cheever

  • Differential regulation of IL-1 production in human monocytes by IFN-gamma and IL-4.

    R P Donnelly;M J Fenton;D S Finbloom;T L Gerrard

Frequent Co-Authors

Howard A. Young
Howard A. Young National Institutes of Health
Thomas J. Rogers
Thomas J. Rogers Temple University
Thomas R. O'Brien
Thomas R. O'Brien National Institutes of Health
Kwong Y. Tsang
Kwong Y. Tsang National Institutes of Health
Nicolai V. Bovin
Nicolai V. Bovin Russian Academy of Sciences
Shioko Kimura
Shioko Kimura National Institutes of Health
Peter L. Collins
Peter L. Collins National Institutes of Health
Matthew J. Fenton
Matthew J. Fenton National Institute of Allergy and Infectious Diseases
Prue H. Hart
Prue H. Hart Telethon Kids Institute
Barbara Rehermann
Barbara Rehermann National Institute of Diabetes and Digestive and Kidney Diseases

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