World's Best Scientists 2026 revealed!
Award Badge
Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
27690
World Ranking
3289
National Ranking
71

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Markus H. Heim is affiliated with the University Hospital of Basel in Switzerland. Their research spans multiple disciplines focusing primarily on medicine and biochemistry, genetics, and molecular biology. Within these fields, Heim's work is concentrated on hepatology, epidemiology, molecular biology, cancer research, and immunology.

Heim's work addresses several key topics, including:

  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hepatitis B Virus Studies
  • RNA modifications and cancer
  • Liver physiology and pathology
  • Liver Disease and Transplantation

Recent significant publications authored or co-authored by Markus H. Heim include:

  • Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids (2021) published in Cell Stem Cell
  • Arginine reprograms metabolism in liver cancer via RBM39 (2023) published in Cell
  • Mechano-modulatory synthetic niches for liver organoid derivation (2020) published in Nature Communications
  • Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis (2021) published in Nature Metabolism
  • Organoids to model liver disease (2020) published in JHEP Reports

Frequently collaborating with other researchers, Heim's notable coauthors include Luigi Terracciano, Sandro Nuciforo, Stefan Wieland, Marie-Anne Meier, and Caner Ercan.

Their work is often published in specialized venues related to liver diseases and molecular biology. Key publication venues include:

  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Genetics
  • Communications Medicine

Heim's research contributes across medicine and life sciences, with over one hundred publications in medicine and fifty in biochemistry, genetics, and molecular biology. Their subfield expertise in hepatology and epidemiology further shapes their scientific outputs.

Best Publications

  • Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

    Andri Rauch;Zoltán Kutalik;Zoltán Kutalik;Patrick Descombes;Tao Cai

  • MicroRNAs 103 and 107 regulate insulin sensitivity

    Mirko Trajkovski;Jean Hausser;Jean Hausser;Jiirgen Soutschek;Bal Bhat

  • Defective STAT signaling by the leptin receptor in diabetic mice.

    Nico Ghilardi;Sandra Ziegler;Adrian Wiestner;Ruedi Stoffel

  • Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

    Julie Lucifora;Yuchen Xia;Florian Reisinger;Ke Zhang

  • Interferon signaling and treatment outcome in chronic hepatitis C

    Magdalena Sarasin-Filipowicz;Edward J. Oakeley;Francois H. T. Duong;Verena Christen

  • Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification.

    M Heim;U.A Meyer

  • Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.

    M. Blum;D.M. Grant;W. McBRIDE;M. Heim

  • Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.

    Asami Hagiwara;Marion Cornu;Nadine Cybulski;Pazit Polak

  • Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway

    Markus H. Heim;Ian M. Kerr;George Stark Stark;James E. Darnell

  • Molecular mechanism of slow acetylation of drugs and carcinogens in humans.

    Martin Blum;Anne Demierre;Denis M. Grant;Markus Heim

  • The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

    Maria L. Balmer;Emma Slack;Andrea de Gottardi;Melissa A. E. Lawson

  • Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

    Luca Quagliata;Matthias S. Matter;Salvatore Piscuoglio;Salvatore Piscuoglio;Leila Arabi

  • The Jak-Stat Pathway: Cytokine Signalling from the Receptor to the Nucleus

    Markus H. Heim

  • Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy

    Magdalena Sarasin-Filipowicz;Magdalena Sarasin-Filipowicz;Jacek Krol;Ilona Markiewicz;Markus H Heim;Markus H Heim

  • Expression of Hepatitis C Virus Proteins Inhibits Signal Transduction through the Jak-STAT Pathway

    Markus H. Heim;Darius Moradpour;Hubert E. Blum

  • mTORC2 Promotes Tumorigenesis via Lipid Synthesis.

    Yakir Guri;Marco Colombi;Eva Dazert;Sravanth K. Hindupur

  • Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.

    M Kagimoto;M Heim;K Kagimoto;T Zeugin

  • Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C.

    Pierre-Yves Bochud;Pierre-Yves Bochud;Tao Cai;Tao Cai;Kathrin Stéphanie Overbeck;Murielle Bochud

  • Innate and adaptive immune responses in HCV infections

    Markus H. Heim;Markus H. Heim;Robert Thimme

  • Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

    Sandro Nuciforo;Isabel Fofana;Matthias S. Matter;Tanja Blumer

Frequent Co-Authors

Luigi Terracciano
Luigi Terracciano University Hospital of Basel
Darius Moradpour
Darius Moradpour University of Lausanne
Andreas Cerny
Andreas Cerny University of Bern
Pierre-Yves Bochud
Pierre-Yves Bochud University of Lausanne
Francesco Negro
Francesco Negro University of Geneva
Zoltán Kutalik
Zoltán Kutalik University of Lausanne
Salvatore Piscuoglio
Salvatore Piscuoglio Humanitas University
Jean-François Dufour
Jean-François Dufour University of Bern
Mirjam B. Zeisel
Mirjam B. Zeisel University of Strasbourg
Charlotte K.Y. Ng
Charlotte K.Y. Ng Humanitas University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry in the USA opens numerous doors in allied health, clinical research, and healthcare management. Many students and professionals are turning to online degrees for flexibility and faster career advancement. For those interested in mental health, the fastest pmhnp program options can lead to in-demand nurse practitioner roles with high job growth.

Nutrition is another field closely connected to biology. Accredited nutrition degree programs provide rapid pathways to qualify for roles in wellness coaching, dietetics, or public health.

For those with an interest in leadership, pursuing the cheapest online mba in healthcare management can be a strategic career move, providing business skills tailored for the healthcare sector.

Additionally, certification matters greatly in medical coding. Considering ccs vs cpc salary differences and requirements may help you determine the best direction if you’re drawn to administrative or analytical health information roles. Each of these online pathways can complement a foundation in Biology and Biochemistry, leading to dynamic and rewarding careers.

Best Scientists Citing Markus H. Heim

Trending Scientists

Recently Published Articles