What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Virus
His main research concerns Virology, Immunology, Genotype, Internal medicine and Allele.
His Virology research is multidisciplinary, incorporating elements of Gene, Chemokine receptor and Severe acute respiratory syndrome coronavirus 2.
The various areas that Thomas R. O'Brien examines in his Immunology study include Cell, Disease and Cohort.
Thomas R. O'Brien has researched Genotype in several fields, including Heteroduplex, Cytokine and Pathogenesis.
His work in the fields of Internal medicine, such as Incidence, Confidence interval, Proportional hazards model and Hilar Cholangiocarcinomas, overlaps with other areas such as International Classification of Diseases for Oncology.
His research in Allele intersects with topics in Promoter, Transcription factor and Interleukin 10.
His most cited work include:
- Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression (866 citations)
- Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant (686 citations)
- A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus (655 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Immunology, Virology, Internal medicine, Genotype and Hepatitis C virus.
The study incorporates disciplines such as Odds ratio and Acquired immunodeficiency syndrome in addition to Immunology.
His study in Virology is interdisciplinary in nature, drawing from both Antibody and Gene, Allele.
His studies deal with areas such as Gastroenterology and Hepatitis B virus as well as Internal medicine.
His Hepatitis C virus study integrates concerns from other disciplines, such as Chronic infection, Viremia, Genome-wide association study and Cancer.
His work deals with themes such as Epidemiology and Cohort study, which intersect with Incidence.
He most often published in these fields:
- Immunology (43.64%)
- Virology (41.82%)
- Internal medicine (29.70%)
What were the highlights of his more recent work (between 2017-2021)?
- Hepatitis C virus (23.64%)
- Virology (41.82%)
- Internal medicine (29.70%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Hepatitis C virus, Virology, Internal medicine, Hepatocellular carcinoma and Gastroenterology.
His work carried out in the field of Hepatitis C virus brings together such families of science as Cancer, Genome-wide association study, Host, Genetic association and Genotype.
His studies in Genotype integrate themes in fields like Immunology and Allele.
His Immunology research is multidisciplinary, relying on both SNP and Single-nucleotide polymorphism.
He combines subjects such as Homozygous genotype, Innate immune system and Pathogen with his study of Virology.
While the research belongs to areas of Internal medicine, Thomas R. O'Brien spends his time largely on the problem of Hepatitis B virus, intersecting his research to questions surrounding Hepatitis C.
Between 2017 and 2021, his most popular works were:
- COVID-19 and emerging viral infections: The case for interferon lambda. (96 citations)
- Weak Induction of Interferon Expression by Severe Acute Respiratory Syndrome Coronavirus 2 Supports Clinical Trials of Interferon-λ to Treat Early Coronavirus Disease 2019. (54 citations)
- Genetic Factors That Affect Spontaneous Clearance of Hepatitis C or B Virus, Response to Treatment, and Disease Progression (16 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Virus
Thomas R. O'Brien focuses on Hepatitis B virus, Hepatitis C virus, Odds ratio, HBsAg and Immunology.
His Hepatitis B virus research includes elements of Gastroenterology and Internal medicine, Hepatitis C.
His Odds ratio research is multidisciplinary, incorporating perspectives in Case-control study, Physiology, Cohort and Confidence interval.
His Immunology study combines topics from a wide range of disciplines, such as Middle East respiratory syndrome, Genome-wide association study and Clinical trial.
His study on Hepatitis D is covered under Virology.
He is interested in Virus diseases, which is a branch of Virology.
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