Eric Gouaux

Research.com Recognitions

• 2013 - W. Alden Spencer Award, College of Physicians and Surgeons

Overview

Best Publications

• Principles of selective ion transport in channels and pumps.

  Eric Gouaux;Roderick MacKinnon

  1294
  Citations

• Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.

  Neali Armstrong;Eric Gouaux

  1285
  Citations

• Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH

  Jayasankar Jasti;Hiroyasu Furukawa;Hiroyasu Furukawa;Eric B. Gonzales;Eric Gouaux;Eric Gouaux

  1201
  Citations

• X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

  Alexander I. Sobolevsky;Michael P. Rosconi;Michael P. Rosconi;Eric Gouaux;Eric Gouaux

  1159
  Citations

• Structure of a glutamate transporter homologue from Pyrococcus horikoshii

  Dinesh Yernool;Olga Boudker;Olga Boudker;Yan Jin;Eric Gouaux;Eric Gouaux

  1156
  Citations

• Principles of activation and permeation in an anion-selective Cys-loop receptor.

  Ryan E. Hibbs;Eric Gouaux

  1088
  Citations

• Subunit arrangement and function in NMDA receptors

  Hiroyasu Furukawa;Satinder K Singh;Romina Mancusso;Eric Gouaux;Eric Gouaux

  1040
  Citations

• Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.

  Toshimitsu Kawate;Jennifer Carlisle Michel;William T. Birdsong;Eric Gouaux;Eric Gouaux

  986
  Citations

• Fluorescence-Detection Size-Exclusion Chromatography for Precrystallization Screening of Integral Membrane Proteins

  Toshimitsu Kawate;Eric Gouaux;Eric Gouaux

  966
  Citations

• Designed protein pores as components for biosensors

  Hagan Bayley;Orit Braha;John Kasianowicz;Eric Gouaux

  964
  Citations

• Structure of a glutamate-receptor ligand-binding core in complex with kainate

  Neali Armstrong;Yu Sun;Guo Qiang Chen;Eric Gouaux

  892
  Citations

• Mechanism of glutamate receptor desensitization

  Yu Sun;Rich Olson;Michelle Horning;Neali Armstrong

  806
  Citations

• Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

  April Goehring;Chia Hsueh Lee;Kevin H. Wang;Jennifer Carlisle Michel

  753
  Citations

• Structural basis for modulation and agonist specificity of HCN pacemaker channels

  William N. Zagotta;Nelson B. Olivier;Kevin D. Black;Edgar C. Young

  716
  Citations

• X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.

  Harini Krishnamurthy;Eric Gouaux

  699
  Citations

• X-ray structures and mechanism of the human serotonin transporter

  Jonathan A. Coleman;Evan M. Green;Eric Gouaux

  644
  Citations

• X-ray structure of dopamine transporter elucidates antidepressant mechanism

  Aravind Penmatsa;Kevin H. Wang;Eric Gouaux

  641
  Citations

• Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core

  Hiroyasu Furukawa;Eric Gouaux

  639
  Citations

• Molecular mechanism of ATP binding and ion channel activation in P2X receptors

  Motoyuki Hattori;Eric Gouaux

  626
  Citations

• A competitive inhibitor traps LeuT in an open-to-out conformation.

  Satinder K. Singh;Chayne L. Piscitelli;Atsuko Yamashita;Eric Gouaux

  612
  Citations