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Neuroscience

D-Index
44
Citations
9399
World Ranking
7097
National Ranking
3075

Overview

Gwenn A. Garden is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with particular focus on Neurology, Physiology, Molecular Biology, Immunology, and Genetics.

The scientist's work largely concentrates on several main topics, including:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • CAR-T cell therapy research
  • Immune cells in cancer
  • Bioinformatics and Genomic Networks
  • Single-cell and spatial transcriptomics
  • Dementia and Cognitive Impairment Research

Gwenn A. Garden has published numerous papers across different prominent scientific journals. Selected recent publications include:

  • "Cytokines in CAR T Cell-Associated Neurotoxicity" (2020) in Frontiers in Immunology
  • "Human microglia show unique transcriptional changes in Alzheimer's disease" (2023) in Nature Aging
  • "Molecular estimation of neurodegeneration pseudotime in older brains" (2020) in Nature Communications
  • "The Neuroscience Multi-Omic Archive: a BRAIN Initiative resource for single-cell transcriptomic and epigenomic data from the mammalian brain" (2022) in Nucleic Acids Research
  • "The pro-inflammatory microRNA miR-155 influences fibrillar β-Amyloid₁₋₄₂ catabolism by microglia" (2021) in Glia

The scientist frequently collaborates with other researchers. Leading coauthors include Suman Jayadev, Katherine E. Prater, C. Dirk Keene, Jessica E. Young, and Shannon E. Rose, reflecting established partnerships evident from multiple joint publications.

Gwenn A. Garden often publishes in journals such as Alzheimer's & Dementia and bioRxiv (Cold Spring Harbor Laboratory), and has also contributed works to UNC Libraries, Nature Communications, and Brain Behavior & Immunity - Health. These venues represent recurring outlets for their research dissemination.

Best Publications

  • Pathways to neuronal injury and apoptosis in HIV-associated dementia

    Marcus Kaul;Gwenn A. Garden;Stuart A. Lipton

  • Association Between Carotid Plaque Characteristics and Subsequent Ischemic Cerebrovascular Events A Prospective Assessment With MRI—Initial Results

    Norihide Takaya;Chun Yuan;Baocheng Chu;Tobias Saam

  • Microglia Biology in Health and Disease

    Gwenn A. Garden;Thomas Möller

  • A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia.

    Stephan J. Guyenet;Stephanie A. Furrer;Vincent M. Damian;Travis D. Baughan

  • Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate

    Kristina M. Adams Waldorf;Jennifer E. Stencel-Baerenwald;Raj P. Kapur;Raj P. Kapur;Colin Studholme

  • Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport.

    Sara K Custer;Gwenn A Garden;Nishi Gill;Udo Rueb

  • Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

    Gwenn A. Garden;Samantha L. Budd;Samantha L. Budd;Elena Tsai;Lisa Hanson

  • Microglia in human immunodeficiency virus-associated neurodegeneration.

    Gwenn A. Garden

  • p53-dependent cell death signaling in neurons.

    Richard S. Morrison;Yoshito Kinoshita;Mark D. Johnson;Weiqun Guo

  • Intercellular (Mis)communication in Neurodegenerative Disease

    Gwenn A. Garden;Albert R. La Spada;Albert R. La Spada

  • Cytokines in CAR T Cell-Associated Neurotoxicity.

    Juliane Gust;Juliane Gust;Rafael Ponce;W. Conrad Liles;Gwenn A. Garden

  • Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.

    Thomas Moller;Frederique Bard;Anindya Bhattacharya;Knut Biber

  • Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA

    Constanza J Cortes;Helen C Miranda;Harald Frankowski;Yakup Batlevi

  • Polyglutamine-Expanded Ataxin-7 Promotes Non-Cell-Autonomous Purkinje Cell Degeneration and Displays Proteolytic Cleavage in Ataxic Transgenic Mice

    Gwenn A. Garden;Randell T. Libby;Ying Hui Fu;Yoshito Kinoshita

  • Predictors of carotid atherosclerotic plaque progression as measured by noninvasive magnetic resonance imaging

    Tobias Saam;Chun Yuan;Baocheng Chu;Norihide Takaya;Norihide Takaya

  • Neuroprotective synergy of erythropoietin and insulin-like growth factor

    Murat Digicaylioglu;Stuart A. Lipton

  • R47H variant of TREM2 associated with Alzheimer disease in a large late-onset family clinical, genetic, and neuropathological study

    Olena Korvatska;James B. Leverenz;Suman Jayadev;Pamela McMillan;Pamela McMillan

  • MicroRNAs mediating CNS inflammation: Small regulators with powerful potential.

    Wei Su;Macarena S. Aloi;Gwenn A. Garden

  • HIV associated neurodegeneration requires p53 in neurons and microglia

    Gwenn A. Garden;Weiqun Guo;Suman Jayadev;Christina Tun

  • Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration

    Gwenn A. Garden;Albert R. La Spada;Albert R. La Spada

Frequent Co-Authors

Albert R. La Spada
Albert R. La Spada University of California, Irvine
C. Dirk Keene
C. Dirk Keene University of Washington
Edwin W. Rubel
Edwin W. Rubel University of Washington
Stuart A. Lipton
Stuart A. Lipton Scripps Research Institute
John F. Neumaier
John F. Neumaier University of Washington
Mark Bothwell
Mark Bothwell University of Washington
Sean Murphy
Sean Murphy University of Washington
Philip L. De Jager
Philip L. De Jager Columbia University
Thomas D. Bird
Thomas D. Bird University of Washington
William B. Dobyns
William B. Dobyns University of Minnesota

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