Sean Murphy

Best Publications

• Synthesis of nitric oxide in CNS glial cells.

  Sean Murphy;Martha L. Simmons;Luis Agullo;Agustina Garcia

  834
  Citations

• Induction of nitric oxide synthase in glial cells.

  Martha L. Simmons;Sean Murphy

  724
  Citations

• Production of nitric oxide by glial cells: regulation and potential roles in the CNS.

  Sean Murphy

  467
  Citations

• The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat.

  S.T. Meller;C. Dykstra;D. Grzybycki;S. Murphy

  463
  Citations

• Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6).

  Steven A. Moore;Elizabeth Yoder;Sean Murphy;Gary R. Dutton

  454
  Citations

• Evidence for an astrocyte-derived vasorelaxing factor with properties similar to nitric oxide.

  Sean Murphy;Robert L. Minor;Greg Welk;David G. Harrison

  277
  Citations

• Cannabinoid activation of PPARα; a novel neuroprotective mechanism

  Y. Sun;S.P.H. Alexander;M.J. Garle;Claire L. Gibson

  270
  Citations

• Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-kappaB binding to DNA.

  Song Kyu Park;Hsin Lee Lin;Sean Murphy

  259
  Citations

• Progesterone for the treatment of experimental brain injury; a systematic review.

  Claire L. Gibson;Laura J. Gray;Philip M. W. Bath;Sean P. Murphy

  221
  Citations

• A systematic review of nitric oxide donors and L-arginine in experimental stroke; effects on infarct size and cerebral blood flow.

  Mark Willmot;Laura J. Gray;Claire L. Gibson;Sean Murphy

  213
  Citations

• Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia.

  Claire L. Gibson;Despina Constantin;Despina Constantin;Malcolm J.W. Prior;Philip M.W. Bath

  209
  Citations

• G-CSF reduces infarct volume and improves functional outcome after transient focal cerebral ischemia in mice.

  Claire L Gibson;Philip M W Bath;Sean P Murphy

  204
  Citations

• Progesterone Enhances Functional Recovery after Middle Cerebral Artery Occlusion in Male Mice

  Claire L Gibson;Sean P Murphy

  198
  Citations

• Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells

  Martha L. Simmons;Sean Murphy

  182
  Citations

• Astrocytes as antigen-presenting cells: expression of IL-12/IL-23.

  Cris S. Constantinescu;Marie Tani;Richard M. Ransohoff;Maria Wysocka

  180
  Citations

• Estrogens and experimental ischemic stroke: a systematic review.

  Claire L Gibson;Laura J Gray;Sean P Murphy;Philip M W Bath

  178
  Citations

• Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus.

  Ning Sun;Dana Grzybicki;Raymond F. Castro;Sean Murphy

  173
  Citations

• Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: a systematic review.

  Mark Willmot;Claire L. Gibson;Laura J. Gray;Sean Murphy

  169
  Citations

• Inflammatory Events at the Blood Brain Barrier: Regulation of Adhesion Molecules, Cytokines, and Chemokines by Reactive Nitrogen and Oxygen Species

  Jean E. Merrill;Seán P. Murphy

  161
  Citations

• Histone Deacetylase Inhibitors Preserve White Matter Structure and Function during Ischemia by Conserving ATP and Reducing Excitotoxicity

  Selva Baltan;Sean P. Murphy;Camelia A. Danilov;Amelia Bachleda

  146
  Citations

• G-CSF suppresses edema formation and reduces interleukin-1β expression after cerebral ischemia in mice

  Claire L. Gibson;Nigel C. Jones;Malcolm J. W. Prior;Philip M. W. Bath

  145
  Citations

• Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and NOS-2 gene-deficient mice.

  Angela K. Loihl;Valerie Asensio;Iain L. Campbell;Sean Murphy

  121
  Citations

• INDUCIBLE NITRIC OXIDE SYNTHASE AND NITRIC OXIDE PRODUCTION BY OLIGODENDROCYTES

  Jean E. Merrill;Sean P. Murphy;Branislava Mitrovic;Allan Mackenzie-Graham

  121
  Citations

• ATP-evoked arachidonic acid mobilization in astrocytes is via a P2Y-purinergic receptor.

  Gretchen Bruner;Sean Murphy

  119
  Citations

• Expression of histone deacetylases in cellular compartments of the mouse brain and the effects of ischemia.

  Selva Baltan;Selva Baltan;Amelia Bachleda;Richard S. Morrison;Sean P. Murphy

  105
  Citations

• Glial nitric oxide and ischemia

  Claire L. Gibson;Teresa C. Coughlan;Sean P. Murphy;Sean P. Murphy

  105
  Citations

• Antagonism of the interleukin‐1 receptor following traumatic brain injury in the mouse reduces the number of nitric oxide synthase‐2‐positive cells and improves anatomical and functional outcomes

  Nigel C. Jones;Malcolm J. W. Prior;Esther Burden-Teh;Charles A. Marsden

  100
  Citations