Paola Barraja

Overview

Best Publications

• Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

  Giovanna Li Petri;Maria Valeria Raimondi;Virginia Spanò;Ralph Holl

  231
  Citations

• Bioactive pyrrole-based compounds with target selectivity.

  Giovanna Li Petri;Virginia Spanò;Roberto Spatola;Ralph Holl

  227
  Citations

• Synthesis and antitumor activity of 2,5-bis(3'-indolyl)-furans and 3,5-bis(3'-indolyl)-isoxazoles, nortopsentin analogues.

  Patrizia Diana;Anna Carbone;Paola Barraja;Gerhard Kelter

  178
  Citations

• 1,3,5-Triazines: A promising scaffold for anticancer drugs development

  Stella Cascioferro;Barbara Parrino;Virginia Spanò;Anna Carbone

  150
  Citations

• An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds

  Stella Cascioferro;Barbara Parrino;Virginia Spanò;Anna Carbone

  131
  Citations

• Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes.

  Marilia Barreca;Virginia Spanò;Alessandra Montalbano;Mercedes Cueto

  129
  Citations

• 3,5-bis(3'-indolyl)pyrazoles, analogues of marine alkaloid nortopsentin: synthesis and antitumor properties.

  Patrizia Diana;Anna Carbone;Paola Barraja;Annamaria Martorana

  123
  Citations

• Synthesis and antitumor properties of 2,5-bis(3'-indolyl)thiophenes: analogues of marine alkaloid nortopsentin.

  Patrizia Diana;Anna Carbone;Paola Barraja;Alessandra Montalbano

  117
  Citations

• Isoindolo[2,1-a]quinoxaline derivatives, novel potent antitumor agents with dual inhibition of tubulin polymerization and topoisomerase I.

  Patrizia Diana;Annamaria Martorana;Paola Barraja;Alessandra Montalbano

  117
  Citations

• Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.

  Anna Carbone;Marzia Pennati;Barbara Parrino;Alessia Lopergolo

  114
  Citations

• Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues.

  Barbara Parrino;Alessandro Attanzio;Virginia Spano;Stella Maria Cascioferro

  81
  Citations

• Indolequinone antitumor agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase. Part 2.

  Elizabeth Swann;Paola Barraja;Ann M. Oberlander;Walter T. Gardipee

  80
  Citations

• Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

  Anna Carbone;Barbara Parrino;Paola Barraja;Virginia Spanò

  80
  Citations

• Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer.

  Virginia Spanò;Barbara Parrino;Anna Carbone;Alessandra Montalbano

  80
  Citations

• Pyrrolo[2,3-d][1,2,3]triazoles as Potential Antineoplastic Agents

  A. Passannanti;P. Diana;P. Barraja;F. Mingoia

  80
  Citations

• Indolo[3,2-c]cinnolines with antiproliferative, antifungal, and antibacterial activity.

  Paola Barraja;Patrizia Diana;Antonino Lauria;Alessandra Passannanti

  77
  Citations

• Comparative study of isoflavone, quinoxaline and oxindole families of anti-angiogenic agents

  Jacqueline L Whatmore;Elizabeth Swann;Paola Barraja;Jeffery J Newsome

  75
  Citations

• Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

  Virginia Spanò;Alessandro Attanzio;Stella Cascioferro;Anna Carbone

  74
  Citations

• Pyrrolo[2,1-c][1,2,4]triazines from 2-diazopyrroles: synthesis and antiproliferative activity.

  Patrizia Diana;Paola Barraja;Antonino Lauria;Alessandra Montalbano

  74
  Citations

• Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)- 1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues.

  A. Carbone;M. Pennati;P. Barraja;A. Montalbano

  72
  Citations

• Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity

  Virginia Spanò;Alessandra Montalbano;Anna Carbone;Barbara Parrino

  69
  Citations