World's Best Scientists 2026 revealed!

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Chemistry

D-Index
48
Citations
11546
World Ranking
15069
National Ranking
74

Overview

Ayman El-Faham is affiliated with King Saud University in Saudi Arabia. Their research spans primarily the fields of Chemistry and Materials Science, focusing intensively on Organic Chemistry and Materials Chemistry. Additional subfields include Oncology, Inorganic Chemistry, and Molecular Biology.

The scientist's work prominently addresses the synthesis and characterization of heterocyclic compounds, a topic featured in 150 of their publications. They also concentrate on crystallization and solubility studies and the use of X-ray diffraction in crystallography, each reflected in over 100 publications. Other notable research areas include metal complex synthesis and properties, click chemistry and its applications, synthesis and reactivity of heterocycles, and the synthesis of tetrazole derivatives.

Frequent co-authors in their research include Saied M. Soliman, Assem Barakat, Hessa H. Al-Rasheed, Matti Haukka, and Fernando Alberício.

Their recent papers illustrate a focus on chemical synthesis and biological activity investigations:

  • "s-Triazine: A Privileged Structure for Drug Discovery and Bioconjugation" (2021, Molecules)
  • "Enhancing the Antifungal Activity of Griseofulvin by Incorporation a Green Biopolymer-Based Nanocomposite" (2021, Polymers)
  • "Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades" (2022, ACS Omega)
  • "Synthesis, structure and biological activity of zinc(II) pincer complexes with 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine" (2020, Inorganica Chimica Acta)
  • "s-Triazine pincer ligands: Synthesis of their metal complexes, coordination behavior, and applications" (2021, Applied Organometallic Chemistry)

The scientist has published extensively in notable venues, including:

  • The Cambridge Structural Database
  • Crystals
  • Molecules
  • Journal of Molecular Structure
  • Inorganics

Best Publications

  • Peptide coupling reagents, more than a letter soup

    Ayman El-Faham;Fernando Albericio

  • Oxyma: An Efficient Additive for Peptide Synthesis to Replace the Benzotriazole‐Based HOBt and HOAt with a Lower Risk of Explosion[1]

    Ramon Subirós-Funosas;Rafel Prohens;Rafael Barbas;Ayman El-Faham;Ayman El-Faham

  • Use of Onium Salt-Based Coupling Reagents in Peptide Synthesis1

    Fernando Albericio;Josep M. Bofill;Ayman El-Faham;Steven A. Kates

  • The uronium/guanidinium Peptide coupling reagents: finally the true uronium salts.

    Louis A. Carpino;Hideko Imazumi;Ayman El-Faham;Fernando J. Ferrer

  • COMU: A Safer and More Effective Replacement for Benzotriazole‐Based Uronium Coupling Reagents

    Ayman El-Faham;Ayman El-Faham;Ramon Subirós Funosas;Rafel Prohens;Fernando Albericio

  • Tetramethylfluoroformamidinium Hexafluorophosphate: A Rapid-Acting Peptide Coupling Reagent for Solution and Solid Phase Peptide Synthesis

    Louis A. Carpino;Ayman El-Faham

  • Advantageous applications of azabenzotriazole (triazolopyridine)-based coupling reagents to solid-phase peptide synthesis

    Louis A. Carpino;Ayman El-Faham;Charles A. Minor;Fernando Albericio

  • Racemization studies during solid-phase peptide synthesis using azabenzotriazole-based coupling reagents

    Louis A. Carpino;Ayman El-Faham;Fernando Albericio

  • EFFICIENCY IN PEPTIDE COUPLING : 1-HYDROXY-7-AZABENZOTRIAZOLE VS 3,4-DIHYDRO-3-HYDROXY-4-OXO-1,2,3-BENZOTRIAZINE

    Louis A. Carpino;Ayman El-Faham;Fernando Albericio

  • Effect of tertiary bases on O-benzotriazolyluronium salt-induced peptide segment coupling

    Louis A. Carpino;Ayman El-Faham

  • Recent development in peptide coupling reagents

    Tarfah I. Al-Warhi;Hassan M.A. Al-Hazimi;Ayman El-Faham;Ayman El-Faham

  • The diisopropylcarbodiimide/ 1-hydroxy-7-azabenzotriazole system: Segment coupling and stepwise peptide assembly

    Louis A Carpino;Ayman El-Faham

  • Choosing the Right Coupling Reagent for Peptides: A Twenty-Five-Year Journey

    Fernando Albericio;Ayman El-Faham;Ayman El-Faham

  • Stepwise Automated Solid Phase Synthesis of Naturally Occurring Peptaibols Using FMOC Amino Acid Fluorides

    Holger Wenschuh;Michael Beyermann;Hanka Haber;Joachim K. Seydel

  • COMU: a third generation of uronium-type coupling reagents.

    Ayman El-Faham;Fernando Albericio

  • Green Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under Green Conditions

    Yahya E. Jad;Gerardo A. Acosta;Thavendran Govender;Hendrik G. Kruger

  • Peptide Coupling in the Presence of Highly Hindered Tertiary Amines

    Louis A. Carpino;Dumitru Ionescu;Ayman El-Faham

  • Aspartimide formation in peptide chemistry: occurrence, prevention strategies and the role of N-hydroxylamines

    Ramon Subirós-Funosas;Ayman El-Faham;Fernando Albericio

  • Synthesis and Biological Evaluation of a Teixobactin Analogue

    Yahya E. Jad;Gerardo A. Acosta;Tricia Naicker;Melissa Ramtahal

  • Peptide synthesis beyond DMF: THF and ACN as excellent and friendlier alternatives

    Yahya E. Jad;Gerardo A. Acosta;Sherine N. Khattab;Beatriz G. de la Torre

  • Morpholine-based immonium and halogenoamidinium salts as coupling reagents in Peptide synthesis1.

    Ayman El-Faham;Fernando Albericio

Frequent Co-Authors

Fernando Albericio
Fernando Albericio University of KwaZulu-Natal
Beatriz G. de la Torre
Beatriz G. de la Torre University of KwaZulu-Natal
Louis A. Carpino
Louis A. Carpino University of Massachusetts Amherst
Matti Haukka
Matti Haukka University of Jyväskylä
Michael Bienert
Michael Bienert Leibniz Association
Mohamed H. El-Newehy
Mohamed H. El-Newehy King Saud University
Muhammad Farooq
Muhammad Farooq Sultan Qaboos University
Hoong-Kun Fun
Hoong-Kun Fun Universiti Sains Malaysia
Michael Beyermann
Michael Beyermann Leibniz Association
Peter Henklein
Peter Henklein Humboldt-Universität zu Berlin

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