Ignazio Castagliuolo spends much of his time researching Clostridium difficile toxin A, Microbiology, Toxin, Clostridium difficile and Immunology. The concepts of his Clostridium difficile toxin A study are interwoven with issues in Mast cell and Substance P. Ignazio Castagliuolo has included themes like Lamina propria, Cell survival and Enterotoxin in his Microbiology study.
His Toxin research integrates issues from Intestinal mucosa, Cholera toxin, Secretion, Saccharomyces boulardii and Vibrio cholerae. His Clostridium difficile study incorporates themes from Immunoglobulin G, Antacid and Colitis. His Immunology study integrates concerns from other disciplines, such as Receptor and Achalasia.
Ignazio Castagliuolo mostly deals with Internal medicine, Microbiology, Immunology, Clostridium difficile toxin A and Cancer research. His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology, Endocrinology and Oncology. His Endocrinology research includes elements of Receptor, Substance P and Neurotensin.
In Microbiology, Ignazio Castagliuolo works on issues like Colitis, which are connected to Cytokine. Ignazio Castagliuolo works mostly in the field of Immunology, limiting it down to concerns involving Enteric nervous system and, occasionally, Herpes simplex virus. His research on Clostridium difficile toxin A also deals with topics like
Ignazio Castagliuolo focuses on Internal medicine, Immunology, Cancer research, Immune system and Gastroenterology. Many of his studies involve connections with topics such as Oncology and Internal medicine. His research in Immunology intersects with topics in Crohn's disease, Intestinal mucosa and Enteric nervous system.
He combines subjects such as Tumor necrosis factor alpha, Oxidative stress, Gene silencing and TLR4 with his study of Cancer research. His work in Cytokine covers topics such as Virus quantification which are related to areas like Microbiology. His work in the fields of Microbiology, such as Colonization, overlaps with other areas such as Immune response gene.
Immunology, Cancer research, Dysplasia, Colorectal cancer and Biochemistry are his primary areas of study. The Immunology study combines topics in areas such as Epithelial–mesenchymal transition, Phenotype, Intestinal mucosa and Enteric nervous system. His Cancer research research incorporates elements of Tumor necrosis factor alpha, Oxidative stress and Cytokine.
Ignazio Castagliuolo has included themes like Gastroenterology, Ulcerative colitis and Adenocarcinoma in his Dysplasia study. His Colorectal cancer study deals with the bigger picture of Internal medicine. His Internal medicine research is multidisciplinary, incorporating perspectives in Probiotic and Saccharomyces boulardii.
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Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis
Paola Brun;Ignazio Castagliuolo;Vincenza Di Leo;Andrea Buda.
American Journal of Physiology-gastrointestinal and Liver Physiology (2007)
Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa.
I Castagliuolo;M F Riegler;L Valenick;J T LaMont.
Infection and Immunity (1999)
Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum.
Charalabos Pothoulakis;Ciaran P. Kelly;Manher A. Joshi;Ning Gao.
Gastroenterology (1993)
Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury
Madhav Bhatia;Ashok K. Saluja;Bernd Hofbauer;Jean Louis Frossard.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Intravenous immunoglobulin therapy for severe Clostridium difficile colitis
J Salcedo;S Keates;C Pothoulakis;M Warny.
Gut (1997)
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.
C Pothoulakis;I Castagliuolo;J T LaMont;A Jaffer.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells
I. Castagliuolo;J. T. Lamont;B. Qiu;S. M. Fleming.
American Journal of Physiology-gastrointestinal and Liver Physiology (1996)
Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum.
I Castagliuolo;J T LaMont;S T Nikulasson;C Pothoulakis.
Infection and Immunity (1996)
Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritis.
I. Castagliuolo;M. Riegler;A. Pasha;S. Nikulasson.
Journal of Clinical Investigation (1998)
p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis
Michel Warny;Andrew C. Keates;Sarah Keates;Ignazio Castagliuolo.
Journal of Clinical Investigation (2000)
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