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John Bienenstock

John Bienenstock

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Immunology
Canada
2023
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Medicine
Canada
2023

D-Index & Metrics

Immunology

D-Index
116
Citations
45442
World Ranking
382
National Ranking
5

Medicine

D-Index
116
Citations
45512
World Ranking
4386
National Ranking
171

Research.com Recognitions

  • 2023 - Research.com Immunology in Canada Leader Award
  • 2023 - Research.com Medicine in Canada Leader Award
  • 2022 - Research.com Immunology in Canada Leader Award
  • 1992 - Fellow of the Royal Society of Canada Academy of Science
  • 1987 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

John Bienenstock was affiliated with McMaster University in Canada. Their research spanned major fields such as Medicine and Neuroscience, with a specific focus on subfields including Microbiology, Molecular Biology, Neurology, Physiology, and Nutrition and Dietetics.

Their work addressed several main topics including:

  • Bacterial Infections and Vaccines
  • Gut microbiota and health
  • Vagus Nerve Stimulation Research
  • Gastrointestinal motility and disorders
  • Diet and metabolism studies
  • Probiotics and Fermented Foods
  • Biochemical Analysis and Sensing Techniques

Among their recent published papers were:

  • Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice, 2020, PLoS ONE
  • Membrane vesicles of Lacticaseibacillus rhamnosus JB-1 contain immunomodulatory lipoteichoic acid and are endocytosed by intestinal epithelial cells, 2021, Scientific Reports
  • The vagus nerve is necessary for the rapid and widespread neuronal activation in the brain following oral administration of psychoactive bacteria, 2020, Neuropharmacology
  • Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson's Disease, 2020, Journal of Parkinson s Disease
  • Gut Microbiome Patterns Associated With Treatment Response in Patients With Major Depressive Disorder: Changements du microbiote intestinal associés à la réponse au traitement chez des patients souffrant de trouble dépressif majeur, 2020, The Canadian Journal of Psychiatry

They published frequently in venues such as:

  • Scientific Reports
  • PLoS ONE
  • Neuropharmacology
  • Journal of Parkinson s Disease
  • The Canadian Journal of Psychiatry

Frequent collaborators included:

  • Andrew M. Stanisz
  • Christine West
  • Wolfgang Kunze
  • Kevin Champagne-Jorgensen
  • Karen-Anne McVey Neufeld

John Bienenstock received several recognitions, including the Fellow of the Royal Society of Canada in 1992 linked to the Academy of Science and the Fellow of the American Association for the Advancement of Science in 1987. They were also a Member of the Association of American Physicians.

Best Publications

  • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve.

    Javier A. Bravo;Paul Forsythe;Marianne V. Chew;Emily Escaravage

  • Reduced anxiety‐like behavior and central neurochemical change in germ‐free mice

    K. M. Neufeld;N. Kang;N. Kang;J. Bienenstock;J. Bienenstock;J. A. Foster;J. A. Foster

  • The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat

    Lieve Desbonnet;Lillian Garrett;Gerard Clarke;John Bienenstock

  • Evidence for a Common Mucosal Immunologic System I. Migration of B Immunoblasts Into Intestinal, Respiratory, and Genital Tissues

    Mark R. McDermott;John Bienenstock

  • Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferations by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen.

    A M Stanisz;D Befus;J Bienenstock

  • Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves

    R H Stead;M Tomioka;G Quinonez;G T Simon

  • Vagal pathways for microbiome-brain-gut axis communication.

    Paul Forsythe;John Bienenstock;Wolfgang A. Kunze

  • Mood and gut feelings.

    Paul Forsythe;Nobuyuki Sudo;Timothy Dinan;Valerie H. Taylor

  • Late cutaneous allergic responses in isolated IgE-dependent reactions

    J. Dolovich;J. Dolovich;F.E. Hargreave;F.E. Hargreave;R. Chalmers;R. Chalmers;K.J. Shier;K.J. Shier

  • Mast cells are closely apposed to nerves in the human gastrointestinal mucosa

    Ron H. Stead;Ron H. Stead;Michael F. Dixon;Michael F. Dixon;Nigel H. Bramwell;Nigel H. Bramwell;Robert H. Riddell;Robert H. Riddell

  • Mast cell heterogeneity: effects of neuroenteric peptides on histamine release.

    F Shanahan;J A Denburg;J Fox;J Bienenstock

  • Bronchial lymphoid tissue. I. Morphologic characteristics.

    Bienenstock J;Johnston N;Perey Dy

  • THE HUMAN SECRETORY IMMUNOGLOBULIN SYSTEM: IMMUNOHISTOLOGICAL LOCALIZATION OF γA, SECRETORY "PIECE," AND LACTOFERRIN IN NORMAL HUMAN TISSUES

    D. R. Tourville;R. H. Adler;J. Bienenstock;T. B. Tomasi

  • Lactobacillus reuteri–induced Regulatory T cells Protect against an Allergic Airway Response in Mice

    Khalil Karimi;Mark D. Inman;John Bienenstock;Paul Forsythe

  • Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

    Sophie Leclercq;Firoz M. Mian;Andrew M. Stanisz;Laure B. Bindels

  • Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius

    Ann M O'Hara;Padraig O'Regan;Aine Fanning;Caitlin O'Mahony

  • Oral Treatment with Live Lactobacillus reuteri Inhibits the Allergic Airway Response in Mice

    Paul Forsythe;Mark D. Inman;John Bienenstock

  • Live Lactobacillus reuteri Is Essential for the Inhibitory Effect on Tumor Necrosis Factor Alpha-Induced Interleukin-8 Expression

    Donglai Ma;Paul Forsythe;John Bienenstock

  • Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects.

    John R. Kelly;Andrew P. Allen;Andriy Temko;William Hutch

  • Pavlovian conditioning of rat mucosal mast cells to secrete rat mast cell protease II.

    Glenda MacQueen;Jean Marshall;Mary Perdue;Shepard Siegel

  • Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells.

    A D Befus;F L Pearce;J Gauldie;P Horsewood

Frequent Co-Authors

Paul Forsythe
Paul Forsythe McMaster University
Judah A. Denburg
Judah A. Denburg McMaster University
Peter B. Ernst
Peter B. Ernst University of California, San Diego
Jerry Dolovich
Jerry Dolovich McMaster University
Jean S. Marshall
Jean S. Marshall Dalhousie University
Jack Gauldie
Jack Gauldie McMaster University
Fergus Shanahan
Fergus Shanahan National University of Ireland
Kenneth L. Rosenthal
Kenneth L. Rosenthal McMaster University
David A. Clark
David A. Clark McMaster University
Hiroshi Matsuda
Hiroshi Matsuda Tokyo University of Agriculture and Technology

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