The scientist’s investigation covers issues in Genetics, Cell biology, Cellular differentiation, Progenitor cell and Cancer research. His work on Regulation of gene expression, Alternative splicing and PRC2 as part of general Genetics study is frequently linked to Polycomb-group proteins, bridging the gap between disciplines. The various areas that he examines in his PRC2 study include Transcription factor and BMI1.
In Cellular differentiation, Bo T. Porse works on issues like Haematopoiesis, which are connected to Wnt signaling pathway. His work carried out in the field of Progenitor cell brings together such families of science as Carboxyfluorescein succinimidyl ester, Myeloid, Myeloid leukemia, Growth factor and Leukemia. His studies deal with areas such as Carcinogenesis and Mutation as well as Cancer research.
Bo T. Porse mostly deals with Cell biology, Haematopoiesis, Cancer research, Myeloid leukemia and Leukemia. His Cell biology research is multidisciplinary, incorporating elements of Genetics, Transcription factor and Cellular differentiation. Bo T. Porse has included themes like Phenotype, Gene and Hematology in his Haematopoiesis study.
In his research on the topic of Cancer research, Ubiquitin is strongly related with Mutation. His work deals with themes such as Myeloid, Epigenetics, CEBPA and Gene expression profiling, which intersect with Myeloid leukemia. Bo T. Porse studied Myeloid and Progenitor cell that intersect with Cell.
Bo T. Porse mainly focuses on Cell biology, Cancer research, CEBPA, Transcription factor and Myeloid leukemia. His research in Cell biology is mostly focused on CD34. He combines subjects such as Haematopoiesis, Apoptosis, Protein kinase B, DNA damage and Chemotherapy with his study of Cancer research.
Bo T. Porse focuses mostly in the field of CEBPA, narrowing it down to matters related to Myeloid and, in some cases, Splicing factor, RNA splicing, Leukemia, Gene knockdown and Regulator. His Transcription factor research is multidisciplinary, relying on both Progenitor cell and Corepressor. Bo T. Porse works mostly in the field of Myeloid leukemia, limiting it down to topics relating to Mutant and, in certain cases, Gene isoform and Gene expression profiling, as a part of the same area of interest.
Cell biology, Progenitor cell, Cell, Myeloid leukemia and CEBPA are his primary areas of study. His study in Progenitor cell is interdisciplinary in nature, drawing from both Myeloid, Enhancer, Gene expression and Function. His Cell research incorporates themes from Computational biology, Stem cell, Retinoic acid and Proteomics.
His biological study focuses on Haematopoiesis. His Myeloid leukemia study incorporates themes from Nuclear export signal, Protein level, RUNX1 and Single-cell analysis. His CEBPA research is classified as research in Transcription factor.
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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
Adrian P. Bracken;Daniela Kleine-Kohlbrecher;Nikolaj Dietrich;Diego Pasini.
Genes & Development (2007)
Bone Marrow-Derived Macrophages (BMM): Isolation and Applications
Joachim Weischenfeldt;Bo Porse.
CSH Protocols (2008)
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
Peggy Kirstetter;Kristina Anderson;Bo T Porse;Sten Eirik W Jacobsen.
Nature Immunology (2006)
E2F Repression by C/EBPα Is Required for Adipogenesis and Granulopoiesis In Vivo
Bo T. Porse;Thomas Å. Pedersen;Xiufeng Xu;Bo Lindberg.
Cell (2001)
BLUEPRINT to decode the epigenetic signature written in blood
David Adams;Lucia Altucci;Stylionos E. Antonarakis;Juan Ballesteros.
Nature Biotechnology (2012)
Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
Diego Pasini;Martina Malatesta;Hye Ryung Jung;Julian Walfridsson.
Nucleic Acids Research (2010)
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Peggy Kirstetter;Mikkel B Schuster;Oksana Bereshchenko;Susan Moore.
Cancer Cell (2008)
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
Joachim Weischenfeldt;Inge Damgaard;David Bryder;Kim Theilgaard-Mönch.
Genes & Development (2008)
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
Faizaan Mohammad;Simon Weissmann;Benjamin Leblanc;Deo P Pandey.
Nature Medicine (2017)
BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis.
Frederik Otzen Bagger;Damir Sasivarevic;Sina Hadi Sohi;Linea Gøricke Laursen.
Nucleic Acids Research (2016)
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