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Biology and Biochemistry
Denmark
2025

D-Index & Metrics

Biology and Biochemistry

D-Index
105
Citations
43285
World Ranking
1191
National Ranking
12

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Denmark Leader Award

Overview

Niels Borregaard is affiliated with the University of Copenhagen in Denmark and has a research profile primarily focused on medical sciences. Their scholarly efforts are centered on topics related to palliative care and end-of-life issues, ion channel regulation and function, grief and bereavement, neuroscience, neuropharmacology, and ethics in medical practice. Their work spans several intersecting subfields including public health, molecular biology, clinical psychology, cellular neuroscience, and general health professions.

The scientist's publication record includes articles concentrated in journals related to medicine and physiology. Key publication venues include:

  • Anästhesie Nachrichten
  • Reviews of physiology, biochemistry and pharmacology
  • Cell Calcium
  • Acta Horticulturae

Their recent papers address diverse topics such as cancer research, ion channel biology, and clinical approaches in end-of-life care. Notable publications include:

  • "Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research," 2020, Reviews of physiology, biochemistry and pharmacology
  • "Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume," 2021, Cell Calcium
  • "Erweiterte Nomenklatur und Terminologie rund um die Situationen am Lebensende," 2023, Anästhesie Nachrichten
  • "Assistierter Suizid: Handlungsempfehlungen für den klinischen Alltag," 2023, Anästhesie Nachrichten
  • "Genetic variations within the promoters of the genes for bitter acid and flavonoid biosynthesis of hop partly explain different levels of bitter acids between cultivars," 2021, Acta Horticulturae

Collaboration is a notable aspect of their research activity, with frequent co-authors contributing to multiple publications. Frequent collaborators include:

  • Barbara Friesenecker
  • Helga Dier
  • Michael Zink
  • Sonja Fruhwald
  • Christian Roden

The primary fields of study for Borregaard's research projects are Medicine and its various subfields, encompassing Public Health, Environmental and Occupational Health, Molecular Biology, Clinical Psychology, and Cellular and Molecular Neuroscience. Their research topics often engage with issues such as:

  • Palliative Care and End-of-Life Issues
  • Ion channel regulation and function
  • Grief, Bereavement, and Mental Health
  • Neuroscience and Neuropharmacology Research
  • Nicotinic Acetylcholine Receptors Study
  • Suicide and Self-Harm Studies
  • Ethics in medical practice

Best Publications

  • The Neutrophil Lipocalin NGAL Is a Bacteriostatic Agent that Interferes with Siderophore-Mediated Iron Acquisition

    David H Goetz;Margaret A Holmes;Niels Borregaard;Martin E Bluhm

  • Neutrophil granules and secretory vesicles in inflammation.

    Mikkel Faurschou;Niels Borregaard

  • Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3

    Adrian F. Gombart;Niels Borregaard;H. Phillip Koeffler

  • Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

    Stephen J Galli;Niels Borregaard;Thomas A Wynn

  • Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3.

    Ole E. Sørensen;Per Follin;Anders H. Johnsen;Jero Calafat

  • Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

    N. Borregaard;J. M. Heiple;E. R. Simons;R. A. Clark

  • The High Molecular Weight Urinary Matrix Metalloproteinase (MMP) Activity Is a Complex of Gelatinase B/MMP-9 and Neutrophil Gelatinase-associated Lipocalin (NGAL) MODULATION OF MMP-9 ACTIVITY BY NGAL

    Li Yan;Niels Borregaard;Lars Kjeldsen;Marsha A. Moses

  • Neutrophils at work

    William M Nauseef;Niels Borregaard

  • Neutrophil granules: a library of innate immunity proteins.

    Niels Borregaard;Ole E. Sørensen;Kim Theilgaard-Mönch

  • The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium.

    Johan D Heilborn;Margareta Frohm Nilsson;Gunnar Kratz;Günther Weber

  • Energy Metabolism of Human Neutrophils during Phagocytosis

    Niels Borregaard;Troels Herlin

  • The Antimicrobial Peptide LL-37 Activates Innate Immunity at the Airway Epithelial Surface by Transactivation of the Epidermal Growth Factor Receptor

    G. Sandra Tjabringa;Jamil Aarbiou;Dennis K. Ninaber;Jan Wouter Drijfhout

  • Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface.

    Linda J. Miller;Dorothy F. Bainton;Niels Borregaard;Timothy A. Springer

  • Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

    Shyra J. Gardai;David A. Hildeman;Steve K. Frankel;Ben B. Whitlock

  • Wound Healing and Expression of Antimicrobial Peptides/Polypeptides in Human Keratinocytes, a Consequence of Common Growth Factors

    Ole E. Sørensen;Jack B. Cowland;Kim Theilgaard-Mönch;Lide Liu

  • The Human Antibacterial Cathelicidin, hCAP-18, Is Synthesized in Myelocytes and Metamyelocytes and Localized to Specific Granules in Neutrophils

    Ole Sørensen;Kristina Arnljots;Jack B. Cowland;Dorothy F. Bainton

  • Neutrophil extracellular traps — the dark side of neutrophils

    Ole E. Sørensen;Niels Borregaard

  • The Human Cationic Antimicrobial Protein (hCAP18), a Peptide Antibiotic, Is Widely Expressed in Human Squamous Epithelia and Colocalizes with Interleukin-6

    Margareta Frohm Nilsson;Bengt Sandstedt;Ole Sørensen;Günther Weber

  • Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases.

    B S Nielsen;N Borregaard;J R Bundgaard;S Timshel

  • Vitamin D-Directed Rheostatic Regulation of Monocyte Antibacterial Responses

    John S. Adams;Songyang Ren;Philip T. Liu;Rene F. Chun

Frequent Co-Authors

Ole E. Sørensen
Ole E. Sørensen Lund University
Anders H. Johnsen
Anders H. Johnsen Rigshospitalet
Adrian F. Gombart
Adrian F. Gombart Oregon State University
Bo T. Porse
Bo T. Porse University of Copenhagen
Jero Calafat
Jero Calafat Antoni van Leeuwenhoek Hospital
Peter Garred
Peter Garred University of Copenhagen
Dorothy F. Bainton
Dorothy F. Bainton University of California, San Francisco
H. Phillip Koeffler
H. Phillip Koeffler Cedars-Sinai Medical Center
Erik Ilsø Christensen
Erik Ilsø Christensen Aarhus University
Finn Cilius Nielsen
Finn Cilius Nielsen Copenhagen University Hospital

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