World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
69
Citations
20572
World Ranking
2012
National Ranking
46

Medicine

D-Index
75
Citations
24383
World Ranking
19049
National Ranking
215

Overview

Xiaojing Ma is affiliated with Shanghai Jiao Tong University in China and has an extensive research profile primarily centered on medicine and biochemistry, genetics, and molecular biology. Their work demonstrates a strong focus on cancer biology, immunology, and molecular mechanisms linked to tumor progression and immune responses.

Their research contributions span several subfields, including:

  • Molecular Biology
  • Oncology
  • Immunology
  • Pulmonary and Respiratory Medicine
  • Surgery

Xiaojing Ma's main areas of study involve key topics such as:

  • Ubiquitin and proteasome pathways
  • Cancer Immunotherapy and Biomarkers
  • Cancer-related Molecular Pathways
  • RNA modifications and cancer
  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction

Their publication record includes papers in respected journals, with notable recent examples including:

  • "Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages," 2020, Nature Communications
  • "UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer," 2022, Theranostics
  • "Single-Cell Profiling of Tumor Immune Microenvironment Reveals Immune Irresponsiveness in Gastric Signet-Ring Cell Carcinoma," 2023, Gastroenterology
  • "Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity," 2021, Cell Reports
  • "Structure of the human UBR5 E3 ubiquitin ligase," 2023, Structure

Xiaojing Ma has published multiple articles in several frequent venues, including:

  • Cancers
  • Frontiers in Oncology
  • Diabetes
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cellular Signalling

Collaboration is an important aspect of their work, as demonstrated by frequent co-authors such as:

  • Mei Song
  • Gang Xiang
  • Huan Wang
  • Ziqi Yu
  • Jing Yu

Best Publications

  • Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

    A. D'andrea;M. Aste-Amezaga;N. M. Valiante;Xiaojing Ma

  • The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells.

    Xiaojing Ma;J. M. Chow;G. Gri;G. Carra

  • Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo

    Sarwish Rafiq;Oladapo O Yeku;Hollie J Jackson;Terence J Purdon

  • Interleukin 10 (IL-10) Inhibits Human Lymphocyte Interferon 3,-Production by Suppressing Natural Killer Cell Stimulatory Factor/IL-12 Synthesis in Accessory Cells By Annalisa D'Andrea, Miguel Aste-Amezaga,

    Nicholas M. Valiante;Xiaojing Ma;Marek Kubin;Giorgio Trinchieri

  • Impaired interleukin 12 production in human immunodeficiency virus-infected patients.

    J Chehimi;S E Starr;I Frank;A D'Andrea

  • Molecular Mechanisms of the Induction of IL-12 and Its Inhibition by IL-10

    Miguel Aste-Amezaga;Xiaojing Ma;Alexandrina Sartori;Giorgio Trinchieri

  • Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

    Fangfang Yin;Rebecca Banerjee;Bobby Thomas;Ping Zhou

  • Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production.

    Annalisa D'Andrea;Xiaojing Ma;Miguel Aste-Amezaga;Carla Paganin

  • Association of Time in Range, as Assessed by Continuous Glucose Monitoring, With Diabetic Retinopathy in Type 2 Diabetes

    Jingyi Lu;Xiaojing Ma;Jian Zhou;Lei Zhang

  • I-PLA2 Activation during Apoptosis Promotes the Exposure of Membrane Lysophosphatidylcholine Leading to Binding by Natural Immunoglobulin M Antibodies and Complement Activation

    Sun Jun Kim;Debra Gershov;Xiaojing Ma;Nathan Brot

  • Tumor Cell Responses to IFNγ Affect Tumorigenicity and Response to IL-12 Therapy and Antiangiogenesis

    Christina M. Coughlin;Kevin E. Salhany;Michael S. Gee;Denise C. LaTemple

  • Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells.

    Sunjung Kim;Keith B. Elkon;Xiaojing Ma

  • Interleukin-12 production by human polymorphonuclear leukocytes.

    Marco A. Cassatella;Lucia Meda;Sara Gasperini;Annalisa D'Andrea

  • The Protooncogene c-Maf Is an Essential Transcription Factor for IL-10 Gene Expression in Macrophages

    Shanjin Cao;Jianguo Liu;Lihua Song;Xiaojing Ma

  • Elevated serum fibroblast growth factor 23 levels as an indicator of lower extremity atherosclerotic disease in Chinese patients with type 2 diabetes mellitus.

    Xingxing He;Xiang Hu;Xiaojing Ma;Hang Su

  • The Circadian Clock Period 2 Gene Regulates Gamma Interferon Production of NK Cells in Host Response to Lipopolysaccharide-Induced Endotoxic Shock

    Jianguo Liu;Guantham Mankani;Xiaoyan Shi;Mark Meyer

  • Regulation of IL-10 and IL-12 production and function in macrophages and dendritic cells.

    Xiaojing Ma;Wenjun Yan;Hua Zheng;Qinglin Du

  • Retinoids Inhibit Interleukin-12 Production in Macrophages through Physical Associations of Retinoid X Receptor and NFκB

    Soon Young Na;Bok Yun Kang;Su Wol Chung;Su Ji Han

  • Inhibition of IL-12 production by thalidomide.

    David R. Moller;Maria Wysocka;Brian M. Greenlee;Xiaojing Ma

  • Regulation of interleukin-12 production in antigen-presenting cells.

    X Ma;G Trinchieri

  • Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

    Jianguo Liu;Shanjin Cao;Lisa M. Herman;Xiaojing Ma

Frequent Co-Authors

Weiping Jia
Weiping Jia Shanghai Jiao Tong University
Giorgio Trinchieri
Giorgio Trinchieri National Institutes of Health
Wei Jia
Wei Jia University of Hong Kong
Henry W. Murray
Henry W. Murray Cornell University
Maria Wysocka
Maria Wysocka University of Pennsylvania
Gang Hu
Gang Hu Pennington Biomedical Research Center
Christopher L. Karp
Christopher L. Karp Bill & Melinda Gates Foundation
Larry M. Wahl
Larry M. Wahl National Institutes of Health
Haifa Shen
Haifa Shen Houston Methodist
Mauro Ferrari
Mauro Ferrari Houston Methodist

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