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D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
16462
World Ranking
8625
National Ranking
581

Overview

Tomohiko Tamura is affiliated with Yokohama City University in Japan. Their research spans several interconnected fields with a primary focus on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

The scientist's main subfields include Molecular Biology, Immunology, Cancer Research, Infectious Diseases, and Oncology. These areas are reflected in the topics they frequently investigate, such as Immunotherapy and Immune Responses, Immune cells in cancer, Epigenetics and DNA Methylation, Cancer, Hypoxia, and Metabolism, COVID-19 Clinical Research Studies, SARS-CoV-2 and COVID-19 Research, and interferon and immune responses.

Tomohiko Tamura's recent notable publications demonstrate a focus on immunological mechanisms, cellular regulation, and disease biomarker identification. Key papers include:

  • Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction (2020, The EMBO Journal)
  • Epigenetic and transcriptional regulation of osteoclast differentiation (2020, Bone)
  • Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach (2021, Scientific Reports)
  • Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease (2021, Nature Communications)
  • OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy (2021, Cell Reports)

The frequent co-authors collaborating with Tomohiko Tamura include:

  • Daisuke Kurotaki
  • Akira Nishiyama
  • Koichi Murakami
  • Atsushi Iwama

Together with co-authors, Tomohiko Tamura has contributed to multiple publications in particular scientific journals. Among the venues where their research is often published are:

  • Cell Reports
  • Blood
  • Scientific Reports
  • Experimental Hematology
  • Nature Communications

Best Publications

  • The IRF Family Transcription Factors in Immunity and Oncogenesis

    Tomohiko Tamura;Hideyuki Yanai;David Savitsky;Tadatsugu Taniguchi

  • HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

    Hideyuki Yanai;Tatsuma Ban;ZhiChao Wang;Myoung Kwon Choi

  • IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity

    Tomohiko Tamura;Prafullakumar Tailor;Kunihiro Yamaoka;Hee Jeong Kong

  • An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

    Tomohiko Tamura;Masahiko Ishihara;Masahiko Ishihara;Marc S. Lamphier;Marc S. Lamphier;Nobuyuki Tanaka;Nobuyuki Tanaka

  • Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.

    ZhiChao Wang;Myoung Kwon Choi;Tatsuma Ban;Hideyuki Yanai

  • Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

    Madhusudan Dey;Chune Cao;Arvin C. Dar;Arvin C. Dar;Tomohiko Tamura

  • ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages

    Tomohiko Tamura;Tokiko Nagamura-Inoue;Zeevik Shmeltzer;Takeshi Kuwata

  • IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

    Takahiro Masuda;Makoto Tsuda;Ryohei Yoshinaga;Hidetoshi Tozaki-Saitoh

  • Regulation of immunity and oncogenesis by the IRF transcription factor family

    David Savitsky;Tomohiko Tamura;Hideyuki Yanai;Tadatsugu Taniguchi

  • Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

    Baohong Zhao;Masamichi Takami;Atsushi Yamada;Xiaogu Wang

  • Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells.

    Hideki Tsujimura;Tomohiko Tamura;Keiko Ozato

  • Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis

    Teruo Yamauchi;Jun Yamauchi;Takeshi Kuwata;Tomohiko Tamura

  • ICSBP/IRF-8: its regulatory roles in the development of myeloid cells.

    Tomohiko Tamura;Keiko Ozato

  • Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages.

    Hee Jeong Kong;Hee Jeong Kong;D. Eric Anderson;Chang Hoon Lee;Moon Kyoo Jang

  • The Bromodomain Protein Brd4 Stimulates G1 Gene Transcription and Promotes Progression to S Phase

    Kazuki Mochizuki;Akira Nishiyama;Moon Kyoo Jang;Anup Dey

  • A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

    Hideo Negishi;Tomoko Osawa;Kentaro Ogami;Xinshou Ouyang

  • Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

    Daisuke Kurotaki;Naoki Osato;Akira Nishiyama;Michio Yamamoto

  • Toll-like receptor signaling and regulation of cytokine gene expression in the immune system.

    Keiko Ozato;Hideki Tsujimura;Tomohiko Tamura

  • The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8.

    Prafullakumar Tailor;Tomohiko Tamura;Hee Jeong Kong;Toru Kubota

  • IRF family proteins and type I interferon induction in dendritic cells.

    Prafullakumar Tailor;Tomohiko Tamura;Keiko Ozato

Frequent Co-Authors

Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Akira Nishiyama
Akira Nishiyama Kagawa University
Tadatsugu Taniguchi
Tadatsugu Taniguchi University of Tokyo
Akihide Ryo
Akihide Ryo Yokohama City University
Herbert C. Morse
Herbert C. Morse National Institute of Allergy and Infectious Diseases
Makoto Tsuda
Makoto Tsuda Kyushu University
Kazuhide Inoue
Kazuhide Inoue Kyushu University
Kenya Honda
Kenya Honda Keio University
Tsuneyasu Kaisho
Tsuneyasu Kaisho Wakayama Medical University
Yutaka Suzuki
Yutaka Suzuki University of Tokyo

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