D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 61 Citations 13,254 156 World Ranking 7425 National Ranking 521

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary scientific interests are in Transcription factor, Cell biology, Interferon regulatory factors, Molecular biology and IRF8. His studies in Transcription factor integrate themes in fields like Interferon, Chromatin immunoprecipitation, Gene expression and Cellular differentiation. His Cell biology research is multidisciplinary, incorporating elements of Antiviral protein, Gene, Immunology and Cell growth.

His Interferon regulatory factors study which covers Regulation of gene expression that intersects with Programmed cell death, IRF1, TCIRG1, DNA damage and T lymphocyte. His research in Molecular biology intersects with topics in Chromatin, Innate immune system and Monocyte differentiation. The study incorporates disciplines such as Cancer research, Internal medicine, Endocrinology and RANKL in addition to IRF8.

His most cited work include:

  • The IRF Family Transcription Factors in Immunity and Oncogenesis (864 citations)
  • HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses (499 citations)
  • An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes (393 citations)

What are the main themes of his work throughout his whole career to date?

Tomohiko Tamura focuses on Transcription factor, Cell biology, IRF8, Immunology and Interferon regulatory factors. The concepts of his Transcription factor study are interwoven with issues in Chromatin, Molecular biology, Interferon and Cellular differentiation. His Cell biology study combines topics in areas such as Dendritic cell, Gene expression and Innate immune system.

He has researched IRF8 in several fields, including Myeloid, Cancer research, Haematopoiesis, Progenitor cell and Monocyte. The Immunology study combines topics in areas such as GATA2 and Macrophage. His Interferon regulatory factors research is multidisciplinary, relying on both Regulation of gene expression, IRF1 and Microglia.

He most often published in these fields:

  • Transcription factor (52.87%)
  • Cell biology (43.95%)
  • IRF8 (40.76%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (43.95%)
  • Transcription factor (52.87%)
  • IRF8 (40.76%)

In recent papers he was focusing on the following fields of study:

Tomohiko Tamura spends much of his time researching Cell biology, Transcription factor, IRF8, Enhancer and Chromatin. Tomohiko Tamura interconnects Gene expression and Epigenetics in the investigation of issues within Cell biology. His Transcription factor research is multidisciplinary, incorporating perspectives in Interferon and Antibody.

The IRF8 study which covers Monocyte that intersects with Mononuclear phagocyte system and Angiotensin II. His research in Chromatin tackles topics such as Regulation of gene expression which are related to areas like Binding site, Chromatin immunoprecipitation and Interferon regulatory factors. The various areas that Tomohiko Tamura examines in his Haematopoiesis study include Molecular biology and Transcriptome.

Between 2017 and 2021, his most popular works were:

  • Interferon stimulation creates chromatin marks and establishes transcriptional memory. (48 citations)
  • Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors (28 citations)
  • Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice. (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary areas of study are Cell biology, Transcription factor, IRF8, Enhancer and Chromatin. His Cell biology research integrates issues from Gene expression, Astrocyte and Clear cell. His research integrates issues of Interferon, Innate immune system, Immune system and Epigenetics in his study of Transcription factor.

Tomohiko Tamura works mostly in the field of IRF8, limiting it down to topics relating to RANKL and, in certain cases, Binding site, Chromatin immunoprecipitation and Interferon regulatory factors, as a part of the same area of interest. His Enhancer research includes themes of Progenitor cell and Stem cell. His work carried out in the field of Chromatin brings together such families of science as Regulation of gene expression and Transcription.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The IRF Family Transcription Factors in Immunity and Oncogenesis

Tomohiko Tamura;Hideyuki Yanai;David Savitsky;Tadatsugu Taniguchi.
Annual Review of Immunology (2008)

1211 Citations

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

Hideyuki Yanai;Tatsuma Ban;ZhiChao Wang;Myoung Kwon Choi.
Nature (2009)

717 Citations

IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity

Tomohiko Tamura;Prafullakumar Tailor;Kunihiro Yamaoka;Hee Jeong Kong.
Journal of Immunology (2005)

466 Citations

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

Tomohiko Tamura;Masahiko Ishihara;Masahiko Ishihara;Marc S. Lamphier;Marc S. Lamphier;Nobuyuki Tanaka;Nobuyuki Tanaka.
Nature (1995)

441 Citations

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.

ZhiChao Wang;Myoung Kwon Choi;Tatsuma Ban;Hideyuki Yanai.
Proceedings of the National Academy of Sciences of the United States of America (2008)

423 Citations

ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages

Tomohiko Tamura;Tokiko Nagamura-Inoue;Zeevik Shmeltzer;Takeshi Kuwata.
Immunity (2000)

419 Citations

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

Madhusudan Dey;Chune Cao;Arvin C. Dar;Arvin C. Dar;Tomohiko Tamura.
Cell (2005)

393 Citations

Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells.

Hideki Tsujimura;Tomohiko Tamura;Keiko Ozato.
Journal of Immunology (2003)

314 Citations

Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis

Teruo Yamauchi;Jun Yamauchi;Takeshi Kuwata;Tomohiko Tamura.
Proceedings of the National Academy of Sciences of the United States of America (2000)

293 Citations

Regulation of immunity and oncogenesis by the IRF transcription factor family

David Savitsky;Tomohiko Tamura;Hideyuki Yanai;Tadatsugu Taniguchi.
Cancer Immunology, Immunotherapy (2010)

277 Citations

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