His primary scientific interests are in Transcription factor, Cell biology, Interferon regulatory factors, Molecular biology and IRF8. His studies in Transcription factor integrate themes in fields like Interferon, Chromatin immunoprecipitation, Gene expression and Cellular differentiation. His Cell biology research is multidisciplinary, incorporating elements of Antiviral protein, Gene, Immunology and Cell growth.
His Interferon regulatory factors study which covers Regulation of gene expression that intersects with Programmed cell death, IRF1, TCIRG1, DNA damage and T lymphocyte. His research in Molecular biology intersects with topics in Chromatin, Innate immune system and Monocyte differentiation. The study incorporates disciplines such as Cancer research, Internal medicine, Endocrinology and RANKL in addition to IRF8.
Tomohiko Tamura focuses on Transcription factor, Cell biology, IRF8, Immunology and Interferon regulatory factors. The concepts of his Transcription factor study are interwoven with issues in Chromatin, Molecular biology, Interferon and Cellular differentiation. His Cell biology study combines topics in areas such as Dendritic cell, Gene expression and Innate immune system.
He has researched IRF8 in several fields, including Myeloid, Cancer research, Haematopoiesis, Progenitor cell and Monocyte. The Immunology study combines topics in areas such as GATA2 and Macrophage. His Interferon regulatory factors research is multidisciplinary, relying on both Regulation of gene expression, IRF1 and Microglia.
Tomohiko Tamura spends much of his time researching Cell biology, Transcription factor, IRF8, Enhancer and Chromatin. Tomohiko Tamura interconnects Gene expression and Epigenetics in the investigation of issues within Cell biology. His Transcription factor research is multidisciplinary, incorporating perspectives in Interferon and Antibody.
The IRF8 study which covers Monocyte that intersects with Mononuclear phagocyte system and Angiotensin II. His research in Chromatin tackles topics such as Regulation of gene expression which are related to areas like Binding site, Chromatin immunoprecipitation and Interferon regulatory factors. The various areas that Tomohiko Tamura examines in his Haematopoiesis study include Molecular biology and Transcriptome.
His primary areas of study are Cell biology, Transcription factor, IRF8, Enhancer and Chromatin. His Cell biology research integrates issues from Gene expression, Astrocyte and Clear cell. His research integrates issues of Interferon, Innate immune system, Immune system and Epigenetics in his study of Transcription factor.
Tomohiko Tamura works mostly in the field of IRF8, limiting it down to topics relating to RANKL and, in certain cases, Binding site, Chromatin immunoprecipitation and Interferon regulatory factors, as a part of the same area of interest. His Enhancer research includes themes of Progenitor cell and Stem cell. His work carried out in the field of Chromatin brings together such families of science as Regulation of gene expression and Transcription.
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The IRF Family Transcription Factors in Immunity and Oncogenesis
Tomohiko Tamura;Hideyuki Yanai;David Savitsky;Tadatsugu Taniguchi.
Annual Review of Immunology (2008)
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
Hideyuki Yanai;Tatsuma Ban;ZhiChao Wang;Myoung Kwon Choi.
IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity
Tomohiko Tamura;Prafullakumar Tailor;Kunihiro Yamaoka;Hee Jeong Kong.
Journal of Immunology (2005)
An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes
Tomohiko Tamura;Masahiko Ishihara;Masahiko Ishihara;Marc S. Lamphier;Marc S. Lamphier;Nobuyuki Tanaka;Nobuyuki Tanaka.
Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.
ZhiChao Wang;Myoung Kwon Choi;Tatsuma Ban;Hideyuki Yanai.
Proceedings of the National Academy of Sciences of the United States of America (2008)
ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages
Tomohiko Tamura;Tokiko Nagamura-Inoue;Zeevik Shmeltzer;Takeshi Kuwata.
Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition
Madhusudan Dey;Chune Cao;Arvin C. Dar;Arvin C. Dar;Tomohiko Tamura.
Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells.
Hideki Tsujimura;Tomohiko Tamura;Keiko Ozato.
Journal of Immunology (2003)
Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis
Teruo Yamauchi;Jun Yamauchi;Takeshi Kuwata;Tomohiko Tamura.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Regulation of immunity and oncogenesis by the IRF transcription factor family
David Savitsky;Tomohiko Tamura;Hideyuki Yanai;Tadatsugu Taniguchi.
Cancer Immunology, Immunotherapy (2010)
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