What is he best known for?
The fields of study he is best known for:
- DNA
- Cell cycle
- Phosphorylation
Biochemistry, Cdc25, Cell biology, CDC2 Protein Kinase and Phosphorylation are his primary areas of study.
The various areas that William G. Dunphy examines in his Cdc25 study include Mitosis and Protein tyrosine phosphatase.
His work on Plasma protein binding as part of general Cell biology research is frequently linked to Xenopus, bridging the gap between disciplines.
His CDC2 Protein Kinase study deals with Wee1 intersecting with CDK-activating kinase.
In Phosphorylation, William G. Dunphy works on issues like Kinase, which are connected to Polo kinase, Molecular cloning and Cyclin-dependent kinase.
His studies in Molecular biology integrate themes in fields like Origin recognition complex and Control of chromosome duplication.
His most cited work include:
- Myt1: A Membrane-Associated Inhibitory Kinase That Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15 (578 citations)
- TopBP1 activates the ATR-ATRIP complex. (560 citations)
- The cdc25 protein contains an intrinsic phosphatase activity (506 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cell biology, Xenopus, Biochemistry, Phosphorylation and DNA replication.
His Cell biology research integrates issues from Chromatin, DNA and CHEK1.
He works mostly in the field of Phosphorylation, limiting it down to topics relating to Cyclin-dependent kinase 1 and, in certain cases, Tyrosine kinase, as a part of the same area of interest.
Many of his research projects under DNA replication are closely connected to Helicase and Recombinant DNA with Helicase and Recombinant DNA, tying the diverse disciplines of science together.
His study looks at the intersection of Cdc25 and topics like Protein tyrosine phosphatase with DUSP6.
His research in Molecular biology intersects with topics in Replication protein A, DNA damage and DNA repair.
He most often published in these fields:
- Cell biology (62.82%)
- Xenopus (52.56%)
- Biochemistry (44.87%)
What were the highlights of his more recent work (between 2006-2021)?
- Cell biology (62.82%)
- Xenopus (52.56%)
- DNA replication (38.46%)
In recent papers he was focusing on the following fields of study:
William G. Dunphy mostly deals with Cell biology, Xenopus, DNA replication, Phosphorylation and DNA.
His biological study spans a wide range of topics, including Chromatin and CHEK1.
Xenopus is intertwined with Biochemistry, MRN complex, Molecular biology and Cell cycle checkpoint in his research.
His research investigates the link between Molecular biology and topics such as DNA repair that cross with problems in Ataxia Telangiectasia Mutated Proteins and DNA damage.
His work in the fields of DNA replication, such as Origin recognition complex, intersects with other areas such as Helicase.
His Phosphorylation research is multidisciplinary, incorporating elements of Cell cycle and Effector.
Between 2006 and 2021, his most popular works were:
- The Rad9-Hus1-Rad1 Checkpoint Clamp Regulates Interaction of TopBP1 with ATR (228 citations)
- Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication (176 citations)
- Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM. (97 citations)
In his most recent research, the most cited papers focused on:
- DNA
- Cell cycle
- Phosphorylation
His primary areas of study are Cell biology, Xenopus, DNA replication, Biochemistry and DNA.
His work on Phosphorylation as part of general Cell biology study is frequently linked to Activator, bridging the gap between disciplines.
His Molecular biology study incorporates themes from Cyclin-dependent kinase, Control of chromosome duplication, Cyclin-dependent kinase 2, Chromatin and Kinase.
His studies deal with areas such as MRE11 Homologue Protein, DNA repair, Ataxia Telangiectasia Mutated Proteins, Rad50 and MRN complex as well as CHEK1.
His research integrates issues of Cell cycle and Origin recognition complex, Eukaryotic DNA replication in his study of Origin of replication.
To a larger extent, he studies Genetics with the aim of understanding Cell cycle.
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