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Biology and Biochemistry

D-Index
63
Citations
21046
World Ranking
10005
National Ranking
4381

Overview

William G. Dunphy is affiliated with the California Institute of Technology in the United States. Their research spans multiple scientific fields, primarily focusing on biochemistry, genetics, and molecular biology as well as aspects of physics and astronomy.

The main areas of study in Dunphy's work include:

  • Biochemistry, Genetics and Molecular Biology
  • Physics and Astronomy

The subfields shaping their research portfolio are:

  • Molecular Biology
  • Cell Biology
  • Atomic and Molecular Physics, and Optics
  • Acoustics and Ultrasonics
  • Instrumentation

Key topics addressed in Dunphy's publications cover:

  • Genomics and Chromatin Dynamics
  • DNA Repair Mechanisms
  • Microtubule and mitosis dynamics
  • Photosynthetic Processes and Mechanisms
  • Mitochondrial Function and Pathology
  • CRISPR and Genetic Engineering
  • Digital Holography and Microscopy

Recent papers by William G. Dunphy include:

  • TopBP1 comes into focus, 2021, Molecular Cell
  • Rif1 restrains the rate of replication origin firing in Xenopus laevis, 2023, Communications Biology
  • Ultrafast and hypersensitive phase imaging of propagating internodal current flows in myelinated axons and electromagnetic pulses in dielectrics, 2022, Nature Communications
  • Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication, 2020, Cell Reports
  • Redox priming promotes Aurora A activation during mitosis, 2020, Science Signaling

William G. Dunphy frequently collaborates with several other researchers, including:

  • Akiko Kumagai
  • Daniel Lim
  • Vladimir Joukov
  • T.J. Rettenmaier
  • James A. Wells

The scientist's work is published across venues such as:

  • Science Signaling
  • Cell Reports
  • Nature Communications
  • Communications Biology
  • Molecular Cell

Best Publications

  • The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

    William G. Dunphy;Leonardo Brizuela;David Beach;John Newport

  • Myt1: A Membrane-Associated Inhibitory Kinase That Phosphorylates Cdc2 on Both Threonine-14 and Tyrosine-15

    Paul R. Mueller;Thomas R. Coleman;Akiko Kumagai;William G. Dunphy

  • TopBP1 activates the ATR-ATRIP complex.

    Akiko Kumagai;Joon Lee;Hae Yong Yoo;William G. Dunphy

  • Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

    William E. Balch;William G. Dunphy;William A. Braell;James E. Rothman

  • The cdc25 protein contains an intrinsic phosphatase activity

    William G. Dunphy;Akiko Kumagai

  • Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts

    Akiko Kumagai;William G. Dunphy

  • The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system.

    Akiko Kumagai;William G. Dunphy

  • Compartmental organization of the Golgi stack.

    William G. Dunphy;James E. Rothman

  • Regulation of the cdc25 protein during the cell cycle in Xenopus extracts.

    Akiko Kumagai;William G. Dunphy

  • Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

    Zijian Guo;Akiko Kumagai;Sophie X. Wang;William G. Dunphy

  • Cdc2 regulatory factors.

    Thomas R. Coleman;William G. Dunphy

  • Claspin, a Novel Protein Required for the Activation of Chk1 during a DNA Replication Checkpoint Response in Xenopus Egg Extracts

    Akiko Kumagai;William G. Dunphy

  • The Xenopus Cdc6 Protein Is Essential for the Initiation of a Single Round of DNA Replication in Cell-Free Extracts

    Thomas R Coleman;Phillip B Carpenter;William G Dunphy

  • Cell cycle regulation of a Xenopus Wee1-like kinase.

    Paul R. Mueller;Thomas R. Coleman;William G. Dunphy

  • Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25

    Akiko Kumagai;William G. Dunphy

  • A lamin-independent pathway for nuclear envelope assembly.

    John W. Newport;Katherine L. Wilson;William G. Dunphy

  • Attachment of terminal N-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the golgi stack

    William G. Dunphy;Ruud Brands;James E. Rothman

  • Positive regulation of Wee1 by Chk1 and 14-3-3 proteins.

    Joon Lee;Akiko Kumagai;William G. Dunphy

  • The decision to enter mitosis

    William G. Dunphy

  • The Rad9-Hus1-Rad1 Checkpoint Clamp Regulates Interaction of TopBP1 with ATR

    Joon Lee;Akiko Kumagai;William G. Dunphy

Frequent Co-Authors

Anna Shevchenko
Anna Shevchenko Max Planck Society
Andrej Shevchenko
Andrej Shevchenko Max Planck Society
Sally Kornbluth
Sally Kornbluth Duke University
Xiao-Fan Wang
Xiao-Fan Wang Duke University
J. Marie Hardwick
J. Marie Hardwick Johns Hopkins University
James E. Rothman
James E. Rothman Yale University
Ashok R. Venkitaraman
Ashok R. Venkitaraman Agency for Science, Technology and Research
Jeffrey C. Rathmell
Jeffrey C. Rathmell Vanderbilt University Medical Center
Benjamin S. Glick
Benjamin S. Glick University of Chicago

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