What is she best known for?
The fields of study she is best known for:
Biochemistry, Phosphorylation, Cell biology, CHEK1 and Cell cycle are her primary areas of study.
Helen Piwnica-Worms has included themes like FKBP, Tyrosine, Signal transduction and Kinase in her Phosphorylation study.
Her work on Protein tyrosine phosphatase and Anti-apoptotic Ras signalling cascade as part of general Cell biology research is often related to KSR1, thus linking different fields of science.
The study incorporates disciplines such as G2-M DNA damage checkpoint, CDC25A, DNA damage and Cancer research in addition to CHEK1.
Her G2-M DNA damage checkpoint study incorporates themes from Cyclin-dependent kinase 1, Cdc25, Molecular biology and DNA repair.
The study incorporates disciplines such as Protein kinase A and DNA replication in addition to Cell cycle.
Her most cited work include:
- Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. (1247 citations)
- Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25 (1178 citations)
- ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. (874 citations)
What are the main themes of her work throughout her whole career to date?
Her primary scientific interests are in Cancer research, Cell biology, Breast cancer, Triple-negative breast cancer and Biochemistry.
The concepts of her Cancer research study are interwoven with issues in Cancer, Metastasis, DNA damage, Immunology and Stem cell.
Her DNA damage research integrates issues from Mutation and DNA repair.
Her studies in Cell biology integrate themes in fields like Cyclin-dependent kinase, Cell cycle, CDC2 Protein Kinase, Molecular biology and Cdc25.
Her work deals with themes such as Mitosis, Cell growth and DNA replication, which intersect with Cell cycle.
Her studies deal with areas such as Tyrosine and Kinase as well as Phosphorylation.
She most often published in these fields:
- Cancer research (33.49%)
- Cell biology (28.90%)
- Breast cancer (22.02%)
What were the highlights of her more recent work (between 2016-2021)?
- Cancer research (33.49%)
- Breast cancer (22.02%)
- Triple-negative breast cancer (20.64%)
In recent papers she was focusing on the following fields of study:
Helen Piwnica-Worms focuses on Cancer research, Breast cancer, Triple-negative breast cancer, Cancer and Internal medicine.
Her Cancer research research is multidisciplinary, incorporating elements of Mass cytometry, Cancer cell, Immune system, Stem cell and In vivo.
Her research integrates issues of Cell, Clinical trial, Chemotherapy, Tumor microenvironment and PI3K/AKT/mTOR pathway in her study of Breast cancer.
She combines subjects such as Radiation therapy, DNA damage and Cell growth with her study of Cancer.
Her DNA damage research includes elements of CHEK1 and Immune checkpoint.
In her research on the topic of Small intestine, Cell biology is strongly related with Gene expression.
Between 2016 and 2021, her most popular works were:
- Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. (170 citations)
- CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib (87 citations)
- Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. (57 citations)
In her most recent research, the most cited papers focused on:
Helen Piwnica-Worms spends much of her time researching Cancer research, Breast cancer, Triple-negative breast cancer, Metastasis and Chemotherapy.
Her study in Cancer research is interdisciplinary in nature, drawing from both Cancer cell, Cancer, Apoptosis, Biomarker and In vivo.
Her study focuses on the intersection of Cancer cell and fields such as Endoplasmic-reticulum-associated protein degradation with connections in the field of Protein kinase A.
Helen Piwnica-Worms works in the field of Cancer, focusing on Cyclin-dependent kinase 2 in particular.
Her biological study spans a wide range of topics, including Myeloid leukemia and Kinase.
Her Triple-negative breast cancer research incorporates themes from Transcriptome and Doxorubicin.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
