2013 - Member of the National Academy of Medicine (NAM)
2007 - Fellow of the American Academy of Arts and Sciences
2007 - Fellow of the American Association for the Advancement of Science (AAAS)
Biochemistry, Phosphorylation, Cell biology, CHEK1 and Cell cycle are her primary areas of study. Helen Piwnica-Worms has included themes like FKBP, Tyrosine, Signal transduction and Kinase in her Phosphorylation study. Her work on Protein tyrosine phosphatase and Anti-apoptotic Ras signalling cascade as part of general Cell biology research is often related to KSR1, thus linking different fields of science.
The study incorporates disciplines such as G2-M DNA damage checkpoint, CDC25A, DNA damage and Cancer research in addition to CHEK1. Her G2-M DNA damage checkpoint study incorporates themes from Cyclin-dependent kinase 1, Cdc25, Molecular biology and DNA repair. The study incorporates disciplines such as Protein kinase A and DNA replication in addition to Cell cycle.
Her primary scientific interests are in Cancer research, Cell biology, Breast cancer, Triple-negative breast cancer and Biochemistry. The concepts of her Cancer research study are interwoven with issues in Cancer, Metastasis, DNA damage, Immunology and Stem cell. Her DNA damage research integrates issues from Mutation and DNA repair.
Her studies in Cell biology integrate themes in fields like Cyclin-dependent kinase, Cell cycle, CDC2 Protein Kinase, Molecular biology and Cdc25. Her work deals with themes such as Mitosis, Cell growth and DNA replication, which intersect with Cell cycle. Her studies deal with areas such as Tyrosine and Kinase as well as Phosphorylation.
Helen Piwnica-Worms focuses on Cancer research, Breast cancer, Triple-negative breast cancer, Cancer and Internal medicine. Her Cancer research research is multidisciplinary, incorporating elements of Mass cytometry, Cancer cell, Immune system, Stem cell and In vivo. Her research integrates issues of Cell, Clinical trial, Chemotherapy, Tumor microenvironment and PI3K/AKT/mTOR pathway in her study of Breast cancer.
She combines subjects such as Radiation therapy, DNA damage and Cell growth with her study of Cancer. Her DNA damage research includes elements of CHEK1 and Immune checkpoint. In her research on the topic of Small intestine, Cell biology is strongly related with Gene expression.
Helen Piwnica-Worms spends much of her time researching Cancer research, Breast cancer, Triple-negative breast cancer, Metastasis and Chemotherapy. Her study in Cancer research is interdisciplinary in nature, drawing from both Cancer cell, Cancer, Apoptosis, Biomarker and In vivo. Her study focuses on the intersection of Cancer cell and fields such as Endoplasmic-reticulum-associated protein degradation with connections in the field of Protein kinase A.
Helen Piwnica-Worms works in the field of Cancer, focusing on Cyclin-dependent kinase 2 in particular. Her biological study spans a wide range of topics, including Myeloid leukemia and Kinase. Her Triple-negative breast cancer research incorporates themes from Transcriptome and Doxorubicin.
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Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
Yolanda Sanchez;Calvin Wong;Calvin Wong;Richard S. Thoma;Richard S. Thoma;Ron Richman;Ron Richman.
Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.
Cheng Yuan Peng;Paul R. Graves;Richard S. Thoma;Zhiqi Wu.
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1.
Hui Zhao;Helen Piwnica-Worms.
Molecular and Cellular Biology (2001)
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element.
James A. DeCaprio;John W. Ludlow;Dennis Lynch;Yusuke Furukawa.
Whole-genome analysis informs breast cancer response to aromatase inhibition
Matthew J. Ellis;Li Ding;Dong Shen;Jingqin Luo.
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase.
Laura L. Parker;Helen Piwnica-Worms.
Use of an oriented peptide library to determine the optimal substrates of protein kinases
Zhou Songyang;Steven Blechner;Nicole Hoagland;Merl F. Hoekstra.
Current Biology (1994)
The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01
Paul R. Graves;Lijia Yu;Julie K. Schwarz;Janis Gales.
Journal of Biological Chemistry (2000)
Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5
K. Baumann;E. M. Mandelkow;J. Biernat;Helen Piwnica-Worms.
FEBS Letters (1993)
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src.
Helen Piwnica-Worms;Kim B Saunders;Thomas M Roberts;Alan E Smith.
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